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23 Cards in this Set
- Front
- Back
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What type of receptor contracts smooth muscle?
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alpha 1
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What type of receptor relaxes smooth muscle?
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beta 2
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What causes mydriasis?
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Contraction of pupillary dilator (symp --> alpha 1)
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What two receptors contract smooth muscle?
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muscarinic (para) and alpha 1 (symp)
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What enhances the drainage of aqueous humor?
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Parasympathetics (muscarinic) through canal of Schlemm
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What causes miosis?
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Pupillary sphincter contraction (parasymp --> muscarinic)
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Inhibitor of parasympathetics causing pupil dilation?
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Atropine
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NT for alpha 1 receptors?
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NE
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Drug used in eye drops to dilate pupil
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PHENYLEPHRINE
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Increases aqueous humor outflow and inhibits formation. Used in solution to treat glaucoma
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Epi
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blocks axoplasmic pump to increase norepinephrine concentrations in vicinity of adrenergic receptors
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Cocaine
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Reverses axoplasmic pump used to diagnose post-ganglionic nerve damage vs. a defect prior to the postganglionic nerve (no reaction means postganglionic nerve defect)
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Amphetamine
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solution used to diagnose simple anisocoria vs Horner’s syndrome
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Cocaine; no effect of cocaine indicates sympathetic dysfunction (if nerves were intact, cocaine would dilate pupil)
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Name 2 agents that release NE
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Cocaine and Amphetemine
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to produce cycloplegia (paralyze ciliary muscle)
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Atropine
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What will nicotine produce in regard to the pupil?
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Nicotine
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Name 2 muscarinic agonists (cause miosis)
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ACh and Pilocarpine
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What can dx 3rd nerve palsy (Atropinic mydriasis)
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Pilocarpine
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If the eye responds to Pilocarpine...
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Damage must be in the nerve
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Name 2 anticholinesterases that produce miosis
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Physostigmine and Ecothiophate
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Alpha 1 receptor antagonist to cause miosis
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Terazonsin (sympth blocker)
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Norepinephrine depleting agent
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Reserpine (no NE to cause pupillary dilation, thus causes miosis)
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What acts on the granule pump?
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Reserpine
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