Neuro 3: Neuro Tumors

Front 1

Where do most NT occur in children?

Back 1

PF

Front 2

Where do most NT occur in adults?

Back 2

Supratentorial (hemishperic)

Front 3

Name 3 cells that would test GFAP +

Back 3

Astrocyte (MAJOR ONE) Oligodendrocyte and Ependymal

Front 4

Which glioma is the most poorly defined?

Back 4

astrocytoma

Front 5

Which glioma is most circumscribed?

Back 5

Oligodendroglioma

Front 6

What NT ALWAYS extends beyond apparent margins and causes asymmetry?

Back 6

Astrocytoma

Front 7

Why do NT cause vasogenic edema?

Back 7

Neovascularization

Front 8

What has eosinophilic cell bodies with abundant, stout processes?

Back 8

Gemistocytic Astrocytoma

Front 9

What NT exhibits serpentine necrosis and pallasading>

Back 9

Glioblastoma Multiforme (GBM)

Front 10

What NT is there an > in VEGF and what does this form?

Back 10

GBM, forming glomeruloid bodies

Front 11

What can a brain stem glioma progress into?

Back 11

GBM

Front 12

Grade of pilocytic astrocytoma?

Back 12

1

Front 13

Where is the primary location of a pilocytic astrocytoma?

Back 13

Cerebellum

Front 14

Which NT is often cystic with mural nodules?

Back 14

Pilocytic Astrocytoma

Front 15

Which NT behaves like a hamartoma?

Back 15

Pilocytic Astrocytoma

Front 16

What do Rosenthal fibers contain?

Back 16

GFAP

Front 17

Grad of Oligodendroglioma?

Back 17

2 or 3

Front 18

Which NT will have microscopic hemorrhages?

Back 18

Oligodendroglioma

Front 19

Why is an oligodndroglioma associated with prolonged survival?

Back 19

Codeletion of 1p and 19q

Front 20

What NT will show halos?

Back 20

Oligo

Front 21

Which NT will show a delicate network of capillaries?

Back 21

Oligo

Front 22

Grade of Ependymoma?

Back 22

2 or 3

Front 23

Where is it most common to get an ependymoma?

Back 23

SC

Front 24

What secondary tumor is common to get with NF2?

Back 24

Ependymoma in SC

Front 25

What NTs would you see asymmetric non-comm hydrocephalus?

Back 25

Ependymoma and Medulloblastoma due to blocked foramen of monroe

Front 26

What age group is an ependymoma common in?

Back 26

children and adolescence

Front 27

BV surrounded by empendymal cells

Back 27

Pseudorosettes

Front 28

Adult varient of ependymoma

Back 28

Myxopapillary (filum terminale)

Front 29

What age group predominates in a medulloblastoma?

Back 29

children

Front 30

Where would you find a medulloblastoma usually?

Back 30

cerebellum (pilocytic too)

Front 31

What is the MOST likely NT to seed into CSF?

Back 31

Medulloblastoma (MORE than ependymoma)

Front 32

What NT shows drop metastisis?

Back 32

Medulloblastoma

Front 33

Where will you see true, Homer-Wright rosettes?

Back 33

Medulloblastoma

Front 34

Which NT may be of mixed origin?

Back 34

Medulloblastoma

Front 35

What is the chormosome abnormality of a medulloblastoma?

Back 35

i(17q)

Front 36

What is the most common tumor in immunosuppressed patients?

Back 36

Primary CNS lymphoma (EBV)

Front 37

What tumor would show large cells around BVs?

Back 37

Primary CNS lymphoma

Front 38

What NT would display Periventricular or Virchow Robin Spaces?

Back 38

Primary CNS Lymphoma

Front 39

Most common tumor to met to the brain?

Back 39

Lung

Front 40

Least common tumor to met to the brain?

Back 40

Prostate

Front 41

Why would you see SAS hemorrhage in CNS Leukemia?

Back 41

< Platelet = bleeding

Front 42

Where would you see transient sludging?

Back 42

CNS leukemia

Front 43

Where would you see penetration along V-R spaces?

Back 43

Luekemia and Lymphoma

Front 44

What tumor has progesterone receptors?

Back 44

Meningioma

Front 45

If mutltiple meningiomas, with acoustic neuromas/gliomas...think what?

Back 45

NF2

Front 46

What NT may be bosselated/polypoid?

Back 46

Meningioma

Front 47

Tumor spreads in a sheet-like fashion along the suface of the dura

Back 47

En Plaque

Front 48

Which NT would display syncytial whorled clusters?

Back 48

Meningioma

Front 49

What NT would display Psammomatous bodies from Ca or syncytial nests?

Back 49

Meningioma

Front 50

Where do most mets occur?

Back 50

Grey-white junction of cortex

Front 51

Plexifrom, or masses of tangled nerves are associated with what?

Back 51

NF1 (Enlargement of limbs)

Front 52

17q11.2

Back 52

NF1

Front 53

22q12

Back 53

NF2

Front 54

>or= 6 cafe au lauit spots

Back 54

NF1

Front 55

Lisch nodules (pigmented hamartomas)

Back 55

NF1 -DISTINGUISHING FACTOR

Front 56

Schwannomas including bilateral acoustic neuromas

Back 56

NF2

Front 57

What NT is very poorly defined?

Back 57

Astrocytoma

Front 58

Which NT are sharply circumscribed?

Back 58

Oligo, Mets, Medduloblastoma

Front 59

Which NT has Rosenthal Fibers

Back 59

Pilocytic Astrocytoma

Front 60

What NTs show En plaque

Back 60

Oligo, Meninioma, Mets

Front 61

What NTs show Ca?

Back 61

Oligo, Meningioma (Psamm)

Front 62

What NTs show NC hydroceph?

Back 62

Epend and Medulloblastoma

Front 63

What NT shows Rosettes?

Back 63

Ependymoma