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12 Cards in this Set
- Front
- Back
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Sympathetic (Adrenergic)
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fight or flight
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Parasympathetic (Cholinergic)
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"Rest-and-relax” or “Rest-and-digest”
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Norepinephrine
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Degraded by two enzymes MAO (monoamine oxidase) & COMT
(catechol-o-methyltransferase) |
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Acetylcholine
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Degraded by AChE (acetylcholinesterase)
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Adrenoreceptors (Adrenergic)
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Alpha: alpha1, alpha2
Beta: beta1, beta2 (Dopaminergic receptors) |
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Cholinoreceptors (Cholinergic)
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Nicotinic
Muscarinic |
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Alpha1 receptors
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found primarily in vascular smooth muscle: eyes, bladder, male sex organs, and prostatic capsule
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Alpha 2 receptors
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found primarily in presynaptic nerve terminals
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beta 1 receptors
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found primarily in the heart
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beta 2 receptors
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found primarily in the lungs & vascular smooth muscle
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Nicotinic receptors
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Lie in the preganglionic portion of sympathetic & parasympathetic, neuromuscular junction, & somatic motor nerves
These receptor sites are NOT blocked by atropine |
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Muscarinic receptors
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Lie in the postganglionic portion of the parasympathetic
Found localized in smooth muscle, cardiac muscle, most exocrine glands, sweat glands, blood vessels & cortical/subcortical areas of CNS These receptor sites are blocked by atropine |
