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52 Cards in this Set
- Front
- Back
The nervous system is divided into which to parts?
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Central & Peripheral
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The CNS consists of which 2 parts?
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Brain and spinal nerves
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The PNS consists which kind of nerves?
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Afferent and Efferent nerves
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What are 2 types of cells in the nervous system?
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Neurons and Neuroglia
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What are the functional units of the NS?
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Neurons
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What are 5 x more common than neurons?
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glial
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What are the 3 parts of the neuron?
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cell body, dendrites, and axon
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What receives information and conveys it to the cell body?
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Dendrites
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What conducts nerve impulses toward the CNS?
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Sensory
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What conducts nerve impulses toward the CNS?
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Sensory Neurons
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What carries impulses out of the CNS?
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Motor Neurons
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What is a Nerve?
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A bundle of axons in the PNS
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What are groups of cell bodies outside the CNS?
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ganglion
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What myelinates several CNS Axons?
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Oligodendrocytes
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What are groups of cell bodies outside the CNS?
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ganglion
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Which cells myelinate PNS axon
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Schwann Cells
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What kind of charge do Cations have?
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positive (K+ or Na+)
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Waht kind of charge do Anions have?
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negative charge (Cl- or proteins)
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What is membreane potential
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separation of opposite charges across plasma membrane
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What is membrane potential?
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separation of opposite charges across plasma membrane
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RMP of most cells is?
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-65 to -85 mV
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At rest most cells have a negative internal charge and ...
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unequal distribution of ions
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At rest most cells have a negative internal charge and unequal distribution of ions.
Results from... |
-large ions being trapped inside cell
-Na+/K+ pump -limited permeability keep Na+ high outside cell -K+ is very permeable and nigh inside cell |
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What is Electrogenic
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3 Na+ pumped for every 2 K+ taken in
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Depolarize
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membrane potential above resting
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Repolarize
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return to normal
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Repolarize
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return to normal
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Repolarize
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return to normal
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Hyperpolarization
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membrane potiental below resting (becomes more negative)
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What does abnormal increase of K+ in blood plasma do?
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-reduces membrane potential
-interferes with electrical activity of heart |
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Voltage gated (VG) Channels
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-opened by depolarization
-closed in resting cells -VG Na+ & K+ channels |
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What is AP/Nerve impulse?
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A wave of change in the membrane potiental due to movement of ions in axon membrane
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Depolarization and Repolarization occur via?
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diffusion and do not require active transport
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Steps in Action Potential
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1. Stimulus opens Na+ channels
2. Voltage sensitive Na+ channels open 3. Na+ channels close |
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Steps in Action Potential
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1. Stimulus opens Na+ channels
2. Voltage sensitive Na+ channels open 3. Na+ channels close 4. Voltage sensitive K+ channels open 5. Na+/K+ pump restores concentration |
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In AP if a single shock is given to a neuron it will either
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"fire" if threshold is reached or
"not fire" if threshold is not reached greater stimulus does not increase size of action potiental |
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What are local anesthetics?
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-block conduction of AP/nerve impulses in sensory axons
-bind to VG Na+ channels -Prevents depolarization and AP |
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Depolarization of axons produced by...
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Inward diffusion of Na+ repolarization is outward diffusion of Ka+
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Coding for stimulus intensity
In a neuron |
-Increased stimulus intensity causes more APs to be produced per second (frequency increased)
-Size of AP's remain constant |
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Coding for Stimulus Intensity
In a Nerve, electrical activity of a nerve can be intensified by |
increasing either frequency or strength
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Coding for Stimulus intensity in a nerve
As the strength (voltage)is increased |
-the # of depolarized axons increases
-increasing the amplitude (size of AP) -AP are graded ( varied) |
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Coding for stimulus intensity in a nerve
As the frequency is increased |
number of impulses conducted increases
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Absolute refractory period
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membrane cannot produce another AP because Na+ channels are inactivated
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relative refractory period
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occurs when VG K+ channels are opened & Na+ channels are recovering from inactivated state
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During Refractory Period, AP can only go away from
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cell body
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During 1st part of repolarization a region of the axon
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can not be stimulated
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During refractory period, can a region of the axon be stimulated?
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during the later part of repolarization, a region of the axon can be stimulated, but it must be a large stimulus to reach threshold
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What does myelination do to nerve impulses?
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Makes conduction of nerve impulses faster
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In The PNS each Schwann cell...
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mylinates axon by wrapping around it
electrically insulates axon |
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Saltatory conduction is
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the rapid passage of action potentials from one node of Ranvier to another in myelinated axons
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The absolute refractory period of a neuron occurs during...
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depolarization and 1st part of repolarization phase
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The conduction of AP's ion myelinated nerve fiber is...
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-saltatory
-without decrement (doesn't decrease) -faster than unmyelinated fibers |