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13 Cards in this Set

  • Front
  • Back

Necrotising enterocolitis

1/1000 live birth


5%NICU ADMISSIONS


10%full term, 45% VLBW


Mean age of onset 12days


Mean age of gestation 32weeks


Mortality 9-28%

Risk factors of NEC

Prematurity/immaturity of GI tract


Enteral feeding


Formula feeding


Cocaine


Toxaemia (mother)


Asphyxia


Umbilical arterial catheter


Congenital heart disease


Polycythaemia


Sepsis


Hypotension


Blood transfusion

Dx NEC

1. SISTEMIC SIGNS


respiratory distress


Apnoea


Bradycardia


Lethargy


Temperature instable


Poor feeding


Hypotension


Poor peripheral perfusion


Metabolic acidosis


Oliguria


Bleeding

ABDOMINAL SIGNS OF NEC

Distension


Tenderness


Gastric aspirates


Vomiting


Ileus


Blood in the stools


Abdominal wall erythema or induration


Persistent localized abdominal mass

Laboratory features of NEC


Thrombocytopenia


Persistent metabolic acidosis


Hyponatremia


High lactate


Crp raise


Blood culture


Electrolyte levels, liver, renal function

RADIOLOGICAL SIGNS NEC

Anteroposterior, lateral decubitus


Fixed bowel loops



Portal or hepatic venous air


Pneumatosis intestinalisPortal or hepatic venous airPneumonitisPneumoperitoneum


intestinalisPortal or hepatic venous airPneumonitisPneumoperitoneum


Pneumonitis


Pneumoperitoneum

NEC - BELL STAGING CRITERIA

Stage 1 suspected


Stage 2 definite


Stage 3 advanced



CLINICAL SIGNS&SYMPTOMS ( PNEUMATOSIS RX) ((PNEUMOPERITONEUM AND CRITICAL ILL)

Management NEC

Ventilatory support



Monitoring perfusion e blood pressure, give volume and inotrops



Metabolic function


(Sodium bicarbonate, lactate)



Nutrition ( discontinue enteral feeds, nasogastric tube on free drainage, start TPN)



INCECTION SCREEN, BROAD SPECTRUM OF ANTIB



platelet transfusion, Red Blood trans



Oliguria, renal failure (acute tubular necrosis)



Neurologic function ( exclude IVH)


Rds

Cxr: low volume lungs with diffuse reticulogranular pattern and air bronchograms

Rds MANAGEMENT

BPD bronchopulmonary dysplasia

Infant born <32 weeks who remain in oxygen for 28 day




MILD: NO SUPPLEMENTAL O2 REQUIREMENT


MODERATE: BPD IS A REQUIREMENT OF SUPPLEMENTAL O2 <30%


SEVERE: >= 30%02 or CPAP



baby >32 weeks with oxy REQUIREMENT for 28 gg

BPD MANAGEMENT

ventilation


Small tidal volume to minimize machanical pulmunary injury


CO2 55-65 mmhg as long as pH remains in the normal range


PEEP between 5-7 cm H20 to minimize atelectasis


Mechanical ventilation Small tidal volume to minimize mechanical pulmunary injuryTargeting partial pressure of CO2 55-65 mmhg as long as pH remains in the normal rangePEEP between 5-7 cm H20 to minimize atelectasis Targeting oxygen saturation to avoid hypoxemia and exposure to excess oxygenNUTRITION incrased requesCAREFUL FLUID MANAGEMENTDIURETIC THERAPY for ventilator dependentSYSTEMIC GLUCOCORTICOID therapy for exceptional infantCaffeineVit ALong term follow up by a multidisciplinary team


Targeting oxygen saturation to avoid hypoxemia and exposure to excess oxygen


Targeting partial pressure of CO2 55-65 mmhg as long as pH remains in the normal rangePEEP between 5-7 cm H20 to minimize atelectasis Targeting oxygen saturation to avoid hypoxemia and exposure to excess oxygenNUTRITION incrased requesCAREFUL FLUID MANAGEMENTDIURETIC THERAPY for ventilator dependentSYSTEMIC GLUCOCORTICOID therapy for exceptional infantCaffeineVit ALong term follow up by a multidisciplinary team



NUTRITION incrased reques



dependent


CAREFUL FLUID MANAGEMENTDIURETIC THERAPY for ventilator dependentSYSTEMIC GLUCOCORTICOID therapy for exceptional infantCaffeineVit ALong term follow up by a multidisciplinary team


SYSTEMIC GLUCOCORTICOID therapy for exceptional infant


DIURETIC THERAPY for ventilator dependentSYSTEMIC GLUCOCORTICOID therapy for exceptional infantCaffeineVit ALong term follow up by a multidisciplinary team


Caffeine


Vit A


Long term follow up by a multidisciplinary team

BPD CXR

Diffuse haziness and a coarse interstitial pattern, which reflect atelectasis , inflammation, pulmonary edema



Lung volume: normal/low



Areas of atelectasis alternate with areas of gas trapping related to airway obstruction from secretions or bronchiolar injury



Severe BPD shows hyperinflation


Streaky densities or cystic areas may be prominent (corresponding to fibrotic changes)