Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
19 Cards in this Set
- Front
- Back
|
What is the gram stain, oxygen requirements, and shape of Neisseria gonorrhoeae?
|
They are gram negative diplococci, obligate aerobes
|
|
|
What is an important confirmation test done on colonies suspected of being N. gonorrhoeae?
|
Positive oxidase test
|
|
|
What are the special growth requirements needed for culturing N. gonorrhoeae?
|
Chocolate agar and increased CO2
|
|
|
What is the major virulence factor for N. gonorrhoeae?
|
The pili (fimbriae) which is the major adhesin and also a vaccine target
|
|
|
What is the major difference between gonococcus and meningococcus in terms of virulence factors?
|
Gonococcus does NOT have a capsule, while meningococcus does
|
|
|
Describe the habitat of gonococcus
|
It is an obligate parasite found in the mucosal surfaces of humans and animals but is NEVER normal flora
|
|
|
Describe the transmission of gonococcus
|
It is transmitted sexually as well as to the newborn during delivery
|
|
|
What is the biggest medical problem associated with chronic infection with gonococcus?
|
Pelvic inflammatory disease in females
|
|
|
Describe an uncomplicated gonococcal infection in males
|
It produces a painful urethritis with a lot of pus formation as well as pharnygitis in homosexuals and conjuctivitis in newborns
|
|
|
Describe an uncomplicated gonococcal infection in females
|
It is an asymptomatic infection of the endocervix with possible spread to the rectum
|
|
|
What is the complicated gonococcal infection in females?
|
Pelvic inflammatory disease leading to infertility, abscesses, peritonitis, and ectopic pregnancies
|
|
|
Describe the disseminated infections of gonococcus
|
It spreads via the bloodstream but doesnt cause sepsis; leads to arthritis, dermatitis, and tenosynovitis
|
|
|
What are the common signs of disseminated gonococcal infection?
|
Arthritis of the wrists and dermatitis on the hands
|
|
|
How is gonococcal infection diagnosed in males?
|
Gram stain of the urethral exudate with growth on Thayer-Martin medium
|
|
|
How is gonoccoccal infection diagnosed in females?
|
A nucleic acid detection test is used on a swab of the endocervix or urin
|
|
|
What is the treatment strategy for gonococcal infection?
|
Two drug therapy is used due to resistance and co-infections with chlamydia
|
|
|
What is the organism that causes Donovanosis and what do the lesions look like?
|
Klebsiella granulomatous; beefy red lesions; often referred to as granuloma inguinale
|
|
|
What are the 4 organisms that should be expected with vaginal/urethral discharge?
|
Chlamydia trachomatis (D-K), N. gonorrhoeae, Mycoplasma hominis, Ureaplasma urealyticum
|
|
|
What 4 organisms should be expected with a genital lesion/ulcer?
|
Chlamydia trochomatis D-K, Haemophilus ducreyi (soft chancre), treponema pallidum, and klebsiella granulosum
|
