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9 Cards in this Set

  • Front
  • Back

Presentation

0.4mg in 1mL glass ampoule


2mg in 5mL (prepared syringe)

Pharmacology

opioid antagonist


action


-prevents or reverses the effects of opioids

Metabolism

By the liver

PEI

ACS and respiratory depression secondary to administration of opioids or related drugs

CI

nil of significance in the above indication

P (2)

-If pt known to be physically dependent on opioids be prepared for combative pt after administration


-neonates

Route

IM


IV

SE

symptoms of opioid withdrawal


-sweating, goose flesh, tremor


-nausea and vomiting


-agitation


-dilatation of pupils, excessive lacrimation


-convulsions

SN OPD

Naloxone may have shorter effects than opioid and may require repeat dose.


Naloxone has no effect if opioid not present


following associated opioid cardiac arrest or head injury, Naloxone should not be administered.


IM & IV


O 1-3 min


P n/a


D 30-45 min