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22 Cards in this Set

  • Front
  • Back

What is correlation?

A measure of linear association between two variables

What type of data do you have if you make one observation per individual?

Independent data

What type of data do you have if you make more than one observation per individual, of the same variable?

Paired data

What is a monotonic relationship?

A positive, non-linear association between two variables

How is Pearsons correlation coefficient reported?

As a value between 1 and - 1

What are the assumptions made when calculating a Pearsons CC?

- That the two variables are continuous and normally distributed



- a linear relationship is present

What is a perfect correlation?

PCC = 1/-1, all data points lie perfectly on line of best fit

Write out the formula for PCC

What is Cov(X, Y)?

The covariance of X and Y, a measure of how they change together

Write the formula for covariance between X and Y

How would you use a table to help calculate a PCC?

Why is it always important to graph the data and not just rely on the PCC as a measure of correlation?

Because many non-linear associations or outliers can influence the PCC to make it appear linear

What is a spurious correlation?

A correlation that seems high but is the result of two unrelated groups that have been combined, each of which have a different correlation

Why is a Spearmans Rank Correlation often used in place of a PCC?

Because it relaxes the assumption of PCC and can be used to show correlations of non-linear data

How do you calculate a SRC?

Rank the data in order from lowest to highest. Then carry out a PCC on the ranks instead of the raw data values

What does a p value tell us about the strength of a correlation?

Nothing - it only tells us whether a correlation is present

What else aside from a PCC can be used to estimate correlation?

A 95CI

What is clinical importance?

The measure of whether a drug produces a large enough effect to be worth using in clinical practice. Is more stringent than statistical significance

What is an MCID?

Minimum clinically important difference

What factors influence the value of an MCID?

The cost effectiveness of a drug, its potential side effects, patient preferences, drug interactions, etc

How do you know if a treatment is statistically significant by looking at its 95CI?

If it crosses 0, it is insignificant

How do you know if a treatment is clinically important?

If its mean difference is above the clinical importance threshold