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32 Cards in this Set
- Front
- Back
The mneumonic GRAIN is for Sarcoid what is it?
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Gammaglobinemia
Rheumatoid Arthritis ACE Interstitial Fibrosis Noncaseating granulomas |
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What are the layers of the skin?
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S. Corneum
S. Lucidum S. Granulosum S. Spinosum S. Basalis |
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If man has facial weakness, frontal balding, cataracts, testicular atrophy, and cardiac involvement what does he have?
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Myotonic dystrophy:
AD, CTG repeat its selective for type 1 fibers |
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Difference between hyperkeratosis and parakaratosis?
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Parakaratosis and retention of the nuclei in stratum corneum
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What is Acantholysis?
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It is the loss of cohesion between keratinocytes and is seen in pemphigus vulgaris
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Inflammatory lesion involving the sub q fat that is involved in coccidiomycosis, histoplasmosis, TB, leprosy, streptococcal infections, sarcoid
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Erthyema nodosum, see it on the shins of people
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Girl that is 5 years old presents with breasts presents with hyperpigmented macules on one side of her back.
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McCune Albright syndrome: its a for of polyostotic fibrous dysplasia where bone is replaced by fibroblasts, collagen and irregular bony trabeculae. Pt has:
- cafe au late spots - precocious puberty - Multiple unilateral bone lesions |
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Cervical disk lesion will affect which root?
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C7, get loss of long thoracic nerve
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Lesin of surgical neck of humerus, anter dislocation of humerus, or intermuscular injection?
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axillary
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Compressin of cervical rib or pancoast tume or lung affects?
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lower trunk of C8, T1
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If use crutch incorrectly what happens?
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radial nerve damage
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If fx SCH, or have problems pronating the wrist?
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median nerve compressed
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If sublux the radius, damage what?
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Get damage to the deep branch of the radial nerve which is all extensors in the forearm
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If dislocate the lunate bone what nerve?
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median nerve
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If fx the hook of the hamate what nerve?
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Ulnar nerve
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Radial nerve innervates what?
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Brachioradialis, extensors, suppinator, triceps
BEST |
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Drainage of the lateral side and dorsum of the foot is done by what vein and goes where?
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short saphenous vein and drains to the popliteal fossa
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young man less than 25 that presents with nocturnal pain in proximal femur that is relieved by aspirin?
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osteoid osteoma. its interlacing trabecular of woven bone surrounded by osteoblasts. Its found in the DIAPHYSIS
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women who is between 20 and 40 that has pain in distal femus. on xray see double bubble sign or soap bubble. with spindle shaped giant cells
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giant cell tumor, its benign
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tumor that protrudes from the metaphysis of long bone, found in men 10-30 years old and is covered by cartilaginous cap
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osteochondroma, its progression to osteosarcoma is rare
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cartilaginous neoplasm found within the bone and its found in the distal extrememities like the hands and feet, you notice an increase in hyaline cartilage?
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ENcondroma
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what other genetic tume is associated with osteosarcoma?
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Retinoblastoma because of Rb gene tumor supporesor loss, chrom 13q
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tumor found in men of 10-20 yrs old and notice on xray that tumor is lifting off the periosteum?
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osteosarcoma, fouind in distal femur, prox tib
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you notice a expansile glistening mass that is located within the bone, its made of cartilage and found in men 30-60yrs old. you notice that it presents in pelvis
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chondrosarcoma, its malignant, located in central portion of skeleton like the prelvis and femur can also be found in spine, scapula, humerus, tibia or femur. it likes to metastasise to lung
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Where is osteomyleitis found in the bone?
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metaphysis because thats where most blood goes to.
s. aureaus kills the bone called sequestra, but if its chronic disease get reactive bone formation called involucrm. pseudomonas infxn will occur in pts who put feet in rubber foot wear. |
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if pt complains of loss of pain and temp in shoulders, elbows, wrists what is wrong?
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syringomyelia, its capelike distribution of loss of sensation due to white commissure blockage because of cyst that forms from CSF.
its a type of neuropathic arthropathy due to nerve loss. |
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pt presents with parotid enlargement, feelings of sand in the eyes, difficulty swallowing crackers, and pain in joints. what are the autoantibodies
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Sjogrens
anti SS-A, SS-B, they are ribonucleoprotein antigens this differs from Sicca syndrome which is dry eyes, dry mouth, chronic bronchitis, but NO ARTHRITIS |
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pt presents with conjunctivitis, arthritis and urethritis, what likely occured prior?
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either a GI or chlymdial infection, pt has Reiters syndrome
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If see wire looping in the kidney with someone who has nephrotic syndrome what disease do they have?
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SLE
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soft, tan colored cauliflower like lesions. what see on histo
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its a verrucae, wart, and see epidermal hyperplasia, hyperkeratosis, koilocytosis.
called verruca vulgaris on hands, and condyloma acuminatum on genitals (caused by HPV) |
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albinism is due to lack of tyrosinase or deletion of tyrosine xporters, where get less tyrosine and therefore less melanin. also can see this with defective neural crest cell migration, this also is associated with what inheritance pattern
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Its Auto Rece, and ex of locus heterogeneity where see mutation of different loci can produce the same phenotype.
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With dermatitis herpetiformis what do you see on histo?
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deposition of IgA at the tips of dermal papillae.
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