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17 Cards in this Set

  • Front
  • Back
what type of collagen is used in bone?
type 1
how is immature bone different from mature?
- not laminated, collagen is irregular and random
- cytes are larger, rounder, and more abundant
- only in young or with injury
what to osteoblasts make?
- osteoid, mainly collagen
- alkaline phosphatase (involved in mineralization)
what receptors do osteobasts have?
- for 1,25-D and parathyroid hormone
- probably involved in Ca ion exchange
where are osteocasts found?
in howship lacunae
what do osteocasts secrete?
acid phosphatase and other proteases
- w/ blasts on surface
- dont form bone yet
- are capable of dividing, unlike basts
bone surface cells
- inactive bast
- cover bone surface not being remodeled
- separate bone surface from ECF, making a separate bone-fluid compartment
periosteum in kids vs adults
- kids - thick w/ blasts and prebasts - active
- adults - thin w/ dormant basts - may be activated by trauma
how is cancellous bone formed and what is its function?
- formed by basts lining the trabeculae
- large surface area, so it responds quickly to physical and metabolic demands (remodeling rate is higher)
1o vs. 2o haversian systems
- 1o formed on growing surface, blasts close in the vessels
- 2o formed form casts that make respoption canals w/ cutting cone - vessels follow, then basts close it up
how are cubiodal bones enlarged
- deep cartilage cells of AC divide and are replaced by bone, and AC cartilage is pushed out
- same w/ ephiphysis
when do epiphysis ossify?
- distal femur at birth
- prox femur at 2-3 months
- distal radius at 3 years
what is 1o spongiosa?
- pink bone parallel to the long bone surrounding blue cartilage
- it only extends into the met a few mm
- little found in adult
rachitic rosary
what the ribs are in ricketts, from accumulation of hypertrophic cartilage cells
when the periphery of bone in the met is is undercut by casts
when the diaphysis is enlarged trasversely by periosteal growth