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5 Cards in this Set
- Front
- Back
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Which neurotransmitter activates spinal cord pattern generators? |
Dopamine |
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Stimulation of which region elicits walking behaviour in cats? |
Mesencephalic locomotor region (MLR) |
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When do signals from MLR go? |
Signals from MLR are projected and processed by the Medial Reticular Formation (MRF) then travel to Spinal Cord |
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Where do signals determining movement/walking speed come from? |
Higher mechanisms like brainstem to start & maintain locomotive patterns (Both MLR & MRF are in brainstem) Strength of these signals determined walking speed |
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How might spinal cord pattern generators be realized? |
Reciprocal inhibition Graham Brown suggested spinal cord 'half-centers' - Each side of spinal cord has set of mutually inhibitory connections between extensor & flexor neurons (reciprocal inhibition) - Afferent fibre from flexor neuron (Flexion Reflex Afferent - FRA) of ipsilateral leg has excitatory projections to the flexor neuron. This maintains and strengthens contraction & inhibits the extensor - FRA of contralateral flexor activates antagonistic extensor neuron, providing an oscillatory locomotion pattern |
