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56 Cards in this Set

  • Front
  • Back
scrip writing legal basis
state regulated fda controlled md
otc
safe,self limited conditions,fda
reg.
legend drugs
must be prescribed by physician
bottle has to be labeled
sched 1
highest research drugs
sched 2
highest abuse opiates oxycontin
high dependence
sched 3
vicodin some abuse,low dep oral or written prescription. up to 5 refills within 6 months
sched 4
oral written unlimited refills ex
sched 5
low abuse minimal
filling out prescription
hand written no cursive dea #
sig
is directions for patient
subscription below inscrip
number of pills
inscription
drug name and dose
superscription rx
for pharmacist
various types of pharmaceutical preps
natural source ex opium
crude drug
dried
pure
example morphine
pharmaceutical prep
the form in which it comes
routes of administration
oral,parenterally im iv subq
sublingual,rectal,inhaled,
pharmokinetics
how drug affects the body
absorption
passive of drug from site of admin to circulation
distribution
how it gets to the organs and tissues from exterstitial
factors that effect drug absorption and distribution
organ blood flow,1)lipid solubility molecular size PBP
lipid soluble
drugs go through easier
first pass effect
drugs abs0rbed reaach liver in hepatic portal
p450 enzyme
is an enzyme needed to breakdown drugs in the liver detoxifies drugs
bioavailability
fraction of the drug that reaches systemic circulation
half life
time needed to eliminate half of
the drug
steady
administration has to equal elimination
loading dose
given to rapidly establish a theurapuetic dose
receptor
proten on cell membrane that drug binds to
agonist drugs
receptors that have high affinity and efficacy
antagonist drugs inhibitor
has high receptor affinity but lack efficacy
renal problems
poor elimination neonates and elderly excretion
liver
lower rate of oxidative reactions in neonates and elderly disease will decrease rate of metabolism
creatinine
kidney clearance
bacteriocidal
will kill organism fast acting
ex pen
bacteriostatic
inhibits growth doesnt kill
contraindication cant be immune comprimised ex. tetracycline
MIC
lowest concentration that inhibits growth
how microbes exhibit resistance
3 major mechanisms IAA
1)inactivation enzymes,2)decreased accumulation by decreased efflux or decreased uptake,3) decrease affinity
role of host factors that affects drug
renal liver function,immune status,allegies
pharkinetic factors that affect drug you chose
half life,peak concentration,absorption,distribution
elimination
general indications for combination drugs
tb give it for
synergistic
2 together are greater than 1
inhibitors bacterial wall synthesis
3 most common pens,cephs,blac inhibitors
there effects
effects cell wall integrity binds to pbp in cytoplasmic inner membrane
betalactam ABx
dont allow assembly maintenance and regulation of cytoplasm
penicillan v
pharyngitis strep
penicillanase resistant
dicloxacillin,nafcillin
ampicillan
endocarditits
piperacillin
pseudomonas
1st generation cefelexin
uncomplicated uti ,skin and soft tissue prophalaxis surgery
2nd generation two
cefuroxime axetil know
for otitis media from hinluenza
3rd generation ceftrixone
single dose gonnerhea
4th generation cefepime
not against mrsa
tp
tic pipericillan
dic naf
penicillase