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19 Cards in this Set

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4 types of Biological Molecules

Fats/Lipids, carbs, proteins, nucleic acids (DNA & RNA)

Chromosome

Comprised of DNA and proteins (DNA double helix wound to make chromosomes)



23 distinct PAIRS, each chromosome is 1 long DNA molecule

Looks like an “X”

What takes place in the nucleolus?

Ribosome synthesis

Chromatin

Made up of protein histones

Human karyotype

See all 23 pairs of chromosomes and what they look like

Gene

Units of heredity


Genes being expressed in the cytoplasm

Human genome

1. All genetic material in the cells (complete set of chromosomes and junk!)


2. Present in every cell in the body (in nucleus)


3. Very large: 3billion bp, >6.5feet of DNA, ~35,000 genes


4. Genes comprise only ~1% of human genome


5. Humans are 99.9% genetically similar (differ by only 3billion bp)


6. Sequence of base pairs determines which trait is expressed

Types of proteins

DNA expression- essentially protein production


Structural proteins- support us like collagen


Hormonal protein- hormone (ex: insulin)


Respiratory proteins- transports oxygen (hemoglobin)


Enzymes- molecules that increase rate of reaction

Chargaff’s Rule

1:1 ratio between adenine and thymine as well as cytosine and guanine (universal rule for all species)

Who elucidated structure of DNA?

Watson and Crick (1953)

Who discovered nuclein in WBC?

Miescher

Who discovered 3 parts of nucleotide? What are the parts?

Levine (1919)


1. Phosphate group


2. Deoxyribose sugar (5 carbons)


3. Nitrogenous base

Alleles

Alternate versions of genes

Genotype

Genetic makeup of an organism


(Dictates the phenotype)

Phenotype

Outward appearance (red hair color)

Diploid

Genetic information of higher organisms is carried in duplicate (2N)

Heterozygous

2 copies of a gene could code different information for the same gene (Aa)

Homozygous

2 identical copies of the same gene

Genetic locus

Specific location where each gene is coded for on a chromatid