Molecular Biology 1

Front 1

Nucleic Acids

Back 1

found in the nucleous contain DNA/RNA

Front 2

Nucleotide Vs. Nucleoside Monomers

Back 2

Nucleotide (Monomer)

• Sugar: 2' deoxyribose (ribose w/o 2' OH)
• Aromatic Base (purine or pyrimidine) on 1' carbon
• Phosphate Groups: 1-3 (3= 2-deoxynucleosidetriphosphate) dNTP

Nucleoside (Monomer)

• Sugar: Ribose with a 2' OH group
• Base: attached to 1' carbon

Front 3

Formation of a Phosphodiester bond and direction

Back 3

Removal of 2 phosphate group on the 5' carbon provides energy for the last phosphate to bond with the 3' hydroxyl of the next nucleotide

Direction: addition of new nucleotides are always added in the 5' --> 3' direction

Front 4

Antiparallel and Parrallel Strands

Back 4

Antiparrallel Strand runs in the opposite direction, allows for complimentary base pairing.