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10 Cards in this Set
- Front
- Back
what does the sympathetic stimulation do to the heart
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increases the permeability to sodium and calcium, speeds up heart rate
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what are the sympathetic neurotransmitters
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1) norepinephrine (sympathetic neuron)
2) epinephrine (adrenal medulla) |
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what ions does sympathetic stimulation affect
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sodium and calcium
I-funny channels and calcium channels |
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what mechanism does symp use to affect the ions
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binds to B1- adrenergic receptors, by promoting the CAMP pathway
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parasympathetic stimulation does what
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slows heart rate
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parasympathetic neurotransmitte
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acetylcholine (AcH)
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what ions does parasymp affect
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increase K+ permeability and decreases Calcium permeabilty to overall hyperpolarize the cell
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what does parasymp bind to
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muscarnic cholinergic receptors
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effect of K+
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parasymp increases K+ permeability so the resting potential starts at a more negative value, take longer to reach threshold
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effect of Ca
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symp: increases calcium, higher hump, faster contraction
parasymp: decreases calcium, slows depolarization rate |