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33 Cards in this Set
- Front
- Back
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Insulin Lispro
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Insulin Lispro
-ultra rapid acting -ultra short acting -10 min -use immediately before meals |
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Insulin Aspart
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Insulin Aspart
-ultra rapid acting -ultra short acting -10 min -use immediately before meals |
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Regular Human Insulin
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Regular Human Insulin
-short acting -30 min -Risk severe hypoglycemia if don't eat within 30 min -Only form of insulin that can be administered IV |
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NPH Insulin
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NPH Insulin
-Intermediate acting |
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Ultralente Insulin
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Ultralente Insulin
-Long acting |
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Glargine
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Glargine
-Long acting, administer once daily -Forms microprecipitates to delay absorption |
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Novolin 70/30
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Novolin 70/30
-Mixture of insulin -Beware excess zinc or protamine |
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Aspart Insulin also known as...
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Aspart Insulin is also known as Novolog
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Lispro Insulin is also known as...
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Lispro Insulin is also known as Humalog
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Humulin R is also known as...
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Humulin R is also known as Regular Insulin
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Novolin R is also known as...
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Novolin R is also known as Regular Insulin
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Humulin N is also known as...
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Humulin N is also known as NPH Insulin
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Novoline N is also known as...
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Novoline N is also known as NPH Insulin
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Humulin L is also known as...
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Humulin L is also known as Lente Insulin
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Novoline L is also known as...
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Novoline L is also known as Lente Insulin
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Humulin U is also known as...
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Humulin U is also known as Ultralente Insulin
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Glargine Insulin is also known as...
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Glargine Insulin is also known as Lantus
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Tolbutamide
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Tolbutamide
-1st generation sulfonylurea -half life 4-5 hrs -rapid action -liver metabolism |
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Chlorpropamide
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Chlorpropamide
-1st generation sulfonylurea -half life 32 hrs -liver metabolism and kidney excretion |
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Tolazamide
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Tolazamide
-1st generation sulfonylurea -half life 7 hrs -slow absorption -short duration of action |
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Glyburide
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Glyburide
-2nd generation sulfonylurea -don't administer in hepatic or renal impairment |
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Glipizide
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Glipizide
-2nd generation sulfonylurea -half life 2-4 hrs -take 30 min before breakfast -don't use in hepatic or renal impairment |
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Glimepiride
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Glimepiride
-2nd generation sulfonylurea -half life 5 hrs -administer once daily -liver metabolism |
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Meglitinides
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Meglitinides
-Non sulfonylurea secretagogues -decrease potassium channel efflux -rapid action, peak 1 hr -Metabolized by CYP3A4 |
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Repaglinide
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Repaglinide
-Non sulfonylurea secretagogues -Metabolized by CYP3A4 |
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Nateglinide
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Nateglinide
-Non sulfonylurea secretagogues -Metabolized by CYP3A4 |
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Biguanides
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Biguanides
-Insulin sensitizer -Don't administer in hepatic or renal impairment |
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Metformin
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Metformin
-Drug in Biguanide class (Insulin Sensitizer) -No hypoglycemia, moderate weight loss -ADR: GI distress, lactic acidosis |
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Thiazolidinediones
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Thiazolidinediones
-Enhance insulin sensitivity by enhancing PPARgamma activity -Redistributes fat from visceral to peripheral -Decreases TAGs -Metabolized by liver P450 -ADR: Weight gain, fluid retention, don't administer in pregnancy |
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Pioglitazone
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Pioglitazone
-Member of Thiazolidinediones class (PPAR gamma agonist) |
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Rosiglitazone
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Rosiglitazone
-Member of Thiazolidinediones class (PPARgamma agonist) |
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Acarbose
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Acarbose
-alpha glucosidase inhibitor (brush border enzymes), so don't break down complex starches, oligosaccharides, disaccharides -ADR: GI distress (severe flatulence, diarrhea, abdominal pain), hypoglycemia when combined with sulfonylurea drug -Don't administer in chronic intestinal disease, IBD, colonic ulceration, intestinal obstruction |
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Miglitol
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Miglitol
-alpha glucosidase inhibitor (brush border enzymes), so don't break down complex starches, oligosaccharides, disaccharides -ADR: GI distress (severe flatulence, diarrhea, abdominal pain), hypoglycemia when combined with sulfonylurea drug -Don't administer in chronic intestinal disease, IBD, colonic ulceration, intestinal obstruction |
