Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
55 Cards in this Set
- Front
- Back
Perprosthetic lucency |
Prosthetic joint infection |
|
Late onset joint infection cause |
>24 month post surgery Due to hematogenous spread |
|
P-ANCA |
Perinuclear pattern - microscopic polyangitis |
|
Organs involved in Microscopic polyangitis |
Lung and kidney |
|
Non granulomatous Necrotizing pauci-immune small vessel vasculitis |
Microscopic polyangitis |
|
Kidney biopsy in microscopic polyangitis |
Pauci-immune Necrotizing crecentric GN |
|
Precautions with pegloticase |
Stop other urate lowering therapy as antibodies develop to pegloticase which would manifest as riding urate level. This would get masked if other urate lowering therapy are used concominantly |
|
Pegloticase mechanism of action |
Porcine derived uricase - lowers irate within hours of administration |
|
Prophylaxis with pegloticase |
Stop urate lowering medications Start anti-inflammatory to prevent attacks - NSAID, prednisone or colchicine |
|
Probenecid contraindication |
GFR <60 i.e. any kidney disease Or Kidney stone |
|
Urate target per ACR |
If no tophi : uric acid <6 If tophi : uric acid <5 |
|
Reactive arthritis trigger |
Chlamydia trachomatis |
|
Ankylosing spondylitis criteria |
Low back pain >3 months In person <45 yr of age Limited spinal movement Elevated inflammatory marker Bilateral sacroilitis on imaging |
|
GAVE syndrome |
Gastric Antral vascular ectasia - linear ectatic vessels that arise from the pylorus |
|
GI bleeding in diffuse Scleroderma |
GAVE syndrome - proliferation of blood vessels in pylorus |
|
Causes of GAVE/watermelon stomach |
autoimmune condition Or Portal hypertension due to cirrhosis |
|
Treatment of GAVE |
Argon plasma coagulation or laser coagulation |
|
Ulcers in hiatal Hernia are called? |
Cameron ulcer - caused by mechanical trauma as the hernia slides up and down Present on the crest of gastric fold |
|
Dieulafoy ulcer are |
Submucosal Arterioles that bleed intermittently. Present on lesser curvature of proximal stomach |
|
Portal hypertensive gastropathy endoscopy appearance |
Mosaic appearance affecting body and fundus |
|
Treatment of Steroid resistant acute gout |
Anakinra Colchicine, steroids or nsaid won't be effective at this point |
|
Indication for surgery in OA |
Pain at rest Pain that awakens at night |
|
Anti jo 1 antibody |
Antisynthetase syndrome |
|
Mechanic's hand |
Hyperkeratotic skin along ulnar aspect of thumb and radial aspect of fingers (index and middle commonly) |
|
Risk factor for 1. RA 2. Gout |
1. Smoking 2. High fructose corn syrup |
|
ESR, CRP abd complements in lupus |
ESR is elevated CRP is generally normal or slightly elevated Hypocomplementia |
|
Acute lupus pneumonitis |
Diffuse pulmonary infiltrate in poorly controlled lupus patient Lymphocytic prodominence on bronchoalveolar lavage |
|
Diarrhea in systemic sclerosis etiology |
1. Decreased mobility leading to SIBO Or 2. Chronic pancreatic inefficiency leading to SIBO |
|
diagnostic test for SIBO |
Glucose hydrogen breath testing Or Jejunal aspirate cultures |
|
Monoarticular minimally painful disease (*knee*) |
Lyme disease |
|
Antibody Associated with retroperitoneal fibrosis |
IgG4 |
|
Anticentromere antibody |
90% specific for Scleroderma Limited cutaneous systemic sclerosis Increased risk of pulmonary arterial hypertension |
|
Anti U1 ribonucleoprotein |
Mixed connective tissue disease |
|
Systems involved in polyarteritis nodosa |
Skin - necrotic ulcers and purpura kidney - hypertension d/t renal artery vasculitis and infarction Nerve - mononueritis multiplex Orchitis - unilateral due to testicular artery involvement Mysentric vasculitis |
|
Polyarteritis nodosa triggers |
Hepatitis B HIV Hairy cell leukemia |
|
Median age of Giant cell arteritis presentation |
70 years |
|
Giant cell arteritis prednisone dose |
If vision loss start with 60mg per day for 1 month. Decrease by 10% weekly if improving |
|
Muscle involvement in inclusion body myositis Muscle involvement in inclusion body myositis Muscle involvement in inclusion body myositis |
Proximal and distal muscles |
|
Eye manifestation with Rheumatoid arthritis |
Scleritis - Painful eye movement, redness, photophobia |
|
Large vessel vasculitis types |
Young age - takayasu vasculitis Old age - giant cell arteritis |
|
PMR relapse treatment |
Increase back to last pre relapse dose of prednisone |
|
Treatment of primary angitis of central nervous system |
Cyclophosphamide |
|
IBS related refractory arthritis treatment |
TNF alpha inhibitor - Adalimumab pegol Certolizumab pegolGolimumabInfliximab Golimumab Infliximab |
|
Differentials for chronic monoarticular synovitis |
Mycobacterium Lyme disease Fungal disease Sarcoidosis |
|
Markers tested in lupus flare |
ESR (elevated) C3/C4 (low) Anti dsDNA (elevated) CRP (elevated if infection) Anti Smith (used only for diagnosis) |
|
Antibodies for Inclusion body myositis |
Anti cytosolic 5' nucleotidase 1A |
|
Antibodies for immune mediated necrotising myositis |
HMG coA reductase antibodies. |
|
Biopsy in immune mediated necrotizing myositis |
Necrotic muscle with minimal inflammatory cells which DO NOT invade the muscle fibers |
|
Differentials for parotid enlargement |
Sjogren syndrome Sarcoidosis HIV associated diffuse lymphocytic infiltrate syndrome IgG4 related disease |
|
Treatment of ILD secondary to scleroderma |
Mycophenolate mofetil |
|
Lofgren syndrome |
Bihilar adenopathy Arthritis (generally ankle joint) Erythema nodosum |
|
Organ involved IgA vasculitis |
Skin - purpura Bowel - abdominal pain, intussusecption Kidney rarely Pulmonary hemorrhage |
|
Risk factor for allopurinol sensitivity |
Han dynasty Chinese population (HLA B*5801) Thai or Korean decent CKD Diuretic use |
|
First line Treatment of ankylosing spondylitis |
NSAID if fails, try TNF-a inhibitors |
|
Trachealization of esophagus is seen in |
Eosinophilic esophagitis |