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82 Cards in this Set

  • Front
  • Back

Congenital Syphilis symptoms

Less than 2


-Snuffles


-Chorioretinitis


-Periosteitis, osteoarthritis


-Nephrotic syndrome



More than 2yo


- raghades


-Saddle nose


-Saber shins


-Mulberry molars/Hutchinson teeth

Becker dystrophy

X linked dystrophin gene mutation


Less severe than Duchenne


Adolescence onset

Congenital syphilis dx

Initial: vdrl or rpr


Confirm: tpi or fta abs or mha to


Most accurate: Dark field microscopy

Edwards syndrome

Physical


Rocker bottom feet


Micrognatia


Low set ears


Clenched hands



Intellectual disability


Congenital heart disease


Death within 1year


Quadscreen all negative


Prophylactic maternal syphilis prior to delivery

Penicillin 4 weeks prior to delivery

Age head lag disappears

4 months

Down syndrome features

Brushfield spots


Flat facies


Prominent epicanthal folds


Single Palmar crease


Gap between 1 and 2nd toes


Causes duodenal atresia, hirschprung and congenital heart disease


Associated to ALL AML and Alzheimer's

Most common cause of stridor in children

Tracheomalacia


2nd mcc congenital subglotic stenosis

Mid Parental height

Boys: dad height plus mother's height + 13cm/2



Girls: mother's height plus dad's height minus 13/2

Differential dx for macrocytic anemia

HAD LBS


Hypothyroidism


Aplastic anemia


Diamond blackfan


Liver disease


Bone marrow infiltration


Syndrome of congenital dyserythropietic anemia

CHARGE

Coloboma of eyes


Heart defects(tof)


Atresia of choanae


Retardation of growth and development


Genitourinary(hypogonadotropic hypogonadism)


Ear

VACTERL

Vertebral


Anal anomalies


Cardiac


TracheoEsophageal fistula


Renal


Limbs

Causes of prolonged QT INTERVAL

Hypokalemia


Hypocalcemia


Drugs: TCAs, erythromycin, tmp and


Jervel and lange Nielsen


Left ventricular hyperthrophy

Clindamycin coverage

Anaerobes, strep and staph



Cause of c diff infection

Toxic shock syndrome

Erythroderma


Hypotension


Fever


Diarrhea


Hypocalcemia

TORCH

Toxoplasmosis


Other: syphilis, varicella zoster, b19, hiv


Rubella


Dmv


Herpes simplex

Asthma predictive index

Major


Parent with asthma


Dx of eczema



Minor


Food allergies


Eosinophilia


Wheezing apart from Colds

Causes of stridor in infant

Intermittent


Aspiration


Viral croup


Electrolyte anomaly



Persistent


Laryngeal anomalies


Mediastinal mass


Vascular ring

Long term complication of underdiagnosed foreign body

Recurrent pneumonia


Atelectasis


Bronchietacsis

False positive treponemal tests causes

Lyme disease


Leptospirosis


Autoimmune disease


Viral infections


False positive non treponemal causes

Lab error


Autoimmune disease


Tb


Lymphoma


Virus(ebv, hepatitis,varicella, gov, measles)


Malaria


Iv drug abuse

Differential for congenital and acquired stridor

Congenital


Laryngothracheomalacia


Subglotic stenosis


Vocal cord paralysis



Infections


Croup


Epiglotitis


Bacterial tracheitis


Retropharyngeal/peritonsillar abscess


Trauma(intubation)


Hypocalcemia, hypothermia


Allergic reaction

Palmar and sole rash differential

Syphilis


Rocky spotted mountain


Hand foot mouth


Kawasaki


Measles


Toxic shock syndrome


Meningococcemia


Bacterial endocarditis


Keratoderma blenorhagica(reiters)


Age maternal retroviral should brr started

>12 weeks

Quadscreen for downs

2nd trimester


Decreased AFP ESTRIOL


increased B hcg, inhibin A

Roseola etiology

Herpes virus 6 or 7

Indications for hospitalization for pneumonia

<3 mo


Hypoxemia


Vomiting dehydration


Underlying condition


Complication


Toxic appearance

Goats milk anemia type

Macrocytic anemia


Folate deficiency

Intubation mnemonics

DOPE


Displacement of tune


Obstruction


Pneumothorax


Equipment failure

Intracranial complications of mastoiditis

. Intracranial complications of mastoiditis (and otitis media) are uncommon and include meningitis, brain abscess, epidural or subdural empyema, and carotid artery and venous sinus thrombosis.

Extracranial complications of mastoiditis

Extracranial complications of mastoiditis (and otitis media) include cholesteatoma, subperiosteal abscess, facial nerve palsy, hearing loss, labyrinthitis, osteomyelitis, and Bezold abscess of the sternocleidomastoid muscle

Etiology of mastoiditis

The bacteria most likely to cause acute mastoiditis in children include Streptococcus pneumoniae, Streptococcus pyogenes, and Staphylococcus aureus. Pseudomonas aeruginosa should be considered as a possible pathogen in children with a history of recurrent otitis media and recent antibiotic use.

Most common cause of hemoptysis in children

Cystic fibrosis

Beighton score

Evaluates joint hypermotility


One point for knee or elbow that extends beyond 10 degrees


9 points in total

Potter sequence associated condition

Autosomal recessive polycystic kidney disease

Causes of short QT

Hypercalcemia


Digitalis


Thyrotoxicosis


Increased sympathetic tone

Di George syndrome

Cleft palate


Abnormal facies


Thymic aplasia


Cardiac defects


Hypocalcemia



Thymus, parathyroid and heart affected

Apt test

Helps differentiate nipple fissure blood from gi tract bleeding



Fetal hemoglobin is resistant unlike maternal

Brugada syndrome

Familial syndrome


Right bundle branch block


St elevation


Syncope or death

Fragile x syndrome

Second most common cause of intellectual disability


Post pubertal macro orchidism


Long face, jaws, ears


Autism


Mvp

Extrapulmonary signs of Mycoplasma

Erythema multiforme


Hemolytic anemia


Arthritis


Carditis


CNS

Mc surgical complications of patients with neuromuscular disorders

Apnea


Cardiac Arrythmias


Malignant hyperthermia

Tumor lysis syndrome electrolyte abnormalities

Hypocalcemia


Hyperkalemia


Hyperphosphatemia


Hyperuricemia

Contraindications to cardiac tamponade

Furosemide

Causes of pericardial efffusions

metabolic (uremia, hypothyroid states), infectious (viral, bacterial, fungal) with or without myocarditis, and autoimmune (lupus, juvenile rheumatoid arthritis, acute rheumatic fever).

“female athlete triad”

disordered eating, amenorrhea, and osteoporosis

McMurray test

holding the patient’s knee in flexion, then rotating the tibia and extending the knee; pain or a palpable click may indicate the presence of a meniscal tear

Valproate side effects

Valproate can cause hyperammonemic encephalopathy without transaminitis.Valproate can cause neutropenia and thrombocytopenia.


Major causes of persistent neonatal Hypoglycemia

Beckwith wiedeman


Nesidioblastosis adenoma


Inborn error of metabolism


Endocrine, pituitary or adrenal

Narrow QRS complex tachycardia causes

SVT


Paroxysmal atrial tachycardia

Causes of double bubble sign

Duodenal Atresia(no distal bowel gas)


Annular pancreas


Midgut volvulus (distal bowel gas)

Influenza complications

Otitis media(mcc)


Staph pneumonia


Myositis


Encephalitis

MC disorders associated to rectal prolapse

Cystic fibrosis


Hirchsprungs


Celiac disease


Parasites

Congenital Rubella infectious for

1 year

Fluconazole indications

Invasive Candida


Inmunocompromised patients


Vulvovaginal Candida


Cryptococcus meningitis

Newborn HIV dx

PCR at birth, 1 and 4 months. Two positive is hiv positive

UTI in patients with indwelling catheters

Enterococcus


Rx ampicillin

Drugs that cause early bleeding in infants

Warfarin


Isoniazid


Rifampin


Phenobarbital

Contraindications of tonsilectomy

Velopharyngeal conditions(cleft palate or cleft uvula)


Anemia


Disorders with hemostasis


Acute airway infection

Large Fontanelle or delayed closure

Congenital HypothyroidismTrisomy 21 (Down Syndrome)Rickets (with Hypophosphatemia)AchondroplasiaIncreased Intracranial Pressure

Small Fontanelle or early closure

Early closure may be normalAlways evaluate for MicrocephalyCraniosynostosis

Indications for Tonsillectomy


recurrent acute or chronic tonsillitis or sinusitis, recurrent acute otitis media or chronic otitis media with effusion, alteration of voice quality because of adenotonsillar hypertrophy, refractory halitosis, peritonsillar abscess, or syndrome of periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA syndrome).

Exertional chest pain

Hypertrophic Cardiomyopathy


Coronary artery disease


Indications for Tonsillectomy


recurrent acute or chronic tonsillitis or sinusitis, recurrent acute otitis media or chronic otitis media with effusion, alteration of voice quality because of adenotonsillar hypertrophy, refractory halitosis, peritonsillar abscess, or syndrome of periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA syndrome).

Indications for Patients with strabism


If constant->referral to ophtalmology


If intermittent->no referral unless 4 months old or older

Peak growth velocity age for females and males

Girls achieve an average peak growth velocity of 8 to 9 cm/year by sexual maturity rating 3.


Boys’ growth velocity peaks at an average of 10 cm/year by sexual maturity rating 4.

Infantile hemangiomas associations

girls, non-Hispanic whites, premature infants, children who are products of multiple gestation, and children of mothers of advanced age

High Risk Hemangiomas

Potentially disguring sites(Nasal tip, perioral, glabela, ear, eyebrow, central facial location >0.5cm, thick or exophytic hemangiomas)


Periocular hemangiomas


Lumbosacral or perineal hemangiomas


Airway hemangioma "beard area" skin hemangioma


Multifocal(>5) infantile hemangiomas

In patients who have undergone abdominal surgery, the new onset of neurologic symptoms should suggest

D-lactic acid acidosis related to bacterial overgrowth syndrome.In patients with suspected malabsorption, an acid stool pH suggests carbohydrate excretion.

Macrocephaly, learning disorder and cafe au lait spots

Neurofibromatosis

Neurofibromatosis type one dx

-6 or more cafe au lait spots, 5mm pre pubertal, 15 mm post pubertal


-2 or more Neurofibromas


-2 or more iris hamartomas


-one or more plexiform Neurofibroma


-axillary freckling


-optic glioma


-Oseous lesion:sphenoid dysplasia or tibial pseudo arthritis


-first degree relative with nf


Leptomeningeal angioma

Sturge weber syndrome

Refeeding syndrome

muscle weakness and fatigue, along with hypocalcemia, hypokalemia, hypomagnesemia, and hypophosphatemia

Pathophysiology of Refeeding syndrome

During periods of starvation, insulin levels fall, promoting release of glucose and free fatty acids for energy. Thyroid hormone levels also are reduced resulting in a lower metabolic rate, and insulin-like growth factor 1 levels fall, reducing protein synthesis. When glycogen stores are exhausted, upregulation of gluconeogenesis from protein catabolism leads to water, vitamin, and mineral depletion. A sudden, marked increase in carbohydrate intake, as with refeeding, will raise serum insulin and lower serum glucagon levels. Increased cellular glucose uptake then promotes intracellular movement of phosphate, potassium, and magnesium, while increased utilization of vitamins (including thiamine) and adenosine triphosphate lead to a deficiency state. Clinically, multiple organ systems may be affected, resulting in muscle weakness, seizures, cardiac arrhythmias, hypotension, and ileus.

Aspirin triad

“aspirin triad,” consists of nasal polyps, acetylsalicylic acid intolerance, and asthma, and is identified in 13% to 40% of patients with nasal polyposis

most common cyanotic congenital heart lesion presenting at birth

Transposition of great vessels

cyanotic congenital heart disease that presents at birth


Transposition of Great Vessels


Pulmonary valve atresia and


severe Ebstein malformation


Single Ventricle Malformation


Hypoplastic heart syndrome

Difference between TGA and pulmonary atresia and Ebstein malformation

Chest radiography can be helpful in distinguishing among these conditions because TGA may show evidence of increased pulmonary blood flow, whereas pulmonary atresia and Ebstein malformation typically show decreased pulmonary blood flow

Children following a vegan diet require increased what nutrients?

iron intake and vitamin B12 supplementation

Criteria for HSP Dx


Purpura or petechiae with lower limb predominance and at least 1 of the following:


-Arthritis or arthralgia,


-Abdominal pain,


-histopathology demonstrating immunoglobulin A deposition, or


-renal involvement demonstrated by hematuria or proteinuria

Allergic rhinitis classification

It may be classified as seasonal or perennial, intermittent or persistent, and mild or moderate to severe.

Allergic Rhinitis physical findings

“Allergic shiners” is the descriptive term for venous congestion and suborbital edema that appears as dark discoloration under the eyes. Dennie-Morgan lines are accentuated lines or folds below the lower lids. The “allergic salute,” pushing the tip of the nose up repeatedly, may lead to a transverse nasal crease. “Allergic facies” consists of an elongated face, high-arched palate, and open mouth breathing.