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20 Cards in this Set
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- Back
- 3rd side (hint)
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Miscellaneous antibacterial agents |
Second line of defense because of emerging resistance, concerns with toxicity, or special activity against specific organisms |
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Chloramphenicol |
Chloromycetin |
PO |
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Used for |
Ricketts, chlamydial diseases. Not used very much because of serious toxic reaction. Drug of choice for typhoid fever |
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Adverse reactions |
Bone marrow injury, blood cell formation disturbances. Neonates - gray baby syndrome. Liver pregnant. Inhibits metabolism of dicoumarol, tolbutamida |
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Clindamycin |
Cleocin |
lincomycin also in this category. Bacteriostatic, IV |
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Used for |
Infections caused by staphylococcus aureus, GI infections. Best drug for acne |
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Adverse reactions |
Lincomycin has marked toxicity and only used when all else fails. For joint, bone, abdominal and female genitourinary tract infections |
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Adverse reactions continued |
Abdominal pain. May result in pseudomembranous colitis |
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Contraindications |
Previous sensitivity to the drug. Babies, moms, people with impaired kidney function, history of GI (particularly colitis infection), liver disease, asthma |
Take doses as scheduled |
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Spectinomycin |
Trobicin |
Bacteriostatic |
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Used for |
Uncomplicated gonorrhea in patients sensitized or resistant to penicillin |
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Adverse reactions |
Headache, dizziness, chills, fever, insomnia. Also pain and soreness at the injection site |
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Contraindications |
Just hypersensitivity to spectinomycin. May be necessary to treat sex partner to prevent reinfection |
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Vancomycin |
Vancocin |
Bactericidal. Requires monitoring of patient |
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Adverse reactions |
Ototoxicity and nephrotoxicity. chills, fever, nausea, rashes and red man syndrome (Flushing) |
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Contraindications |
Patients with previous hearing loss, kids, moms, old people. Impaired kidney function and renal failure |
Call doctor if you have ringing in your ears |
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Linezolid - an oxazolidinone |
Zyvox |
Bacteriostatic |
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Used for |
Totally synthetic antibiotic. GP aerobics organisms, staph, strep and enterococci that are highly virulent |
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Adverse reactions |
Nausea, vomiting, diarrhea |
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Contraindications |
Dopamine, epinephrine or pseudoephedrine. Blood pressure and heart rate should be monitored. Some foods and beverages high in tyramine -- aged cheese, air dried Meats, chocolate, fish, sauerkraut, red wines, tap beers and soy sauce |
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