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7 Cards in this Set
- Front
- Back
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To what virus family does hepatitis A virus belong?
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Picornavirus. (Smallest(27-nm diameter) nonenveloped icosahedral single stranded positive sense RNA virus.
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How many immunological strains of HAV are there?
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Although HAV genome may vary by 20%, there is only one serotype. Infection confers immunity from all HAV strains. Transmitted by fecal-oral route.
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How common is HAV infection?
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HAV is almost universal in developing nations and in about 1/3 of adults in the US, have evidence of past infection.
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Is there a cgronic HAV carrier state?
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No. HAV usually cause a self limiting acute reaction with complete recovery.
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How is it possible to distinguish between active and past HAV infection?
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Active HAV infection is characterized by anti-HAV IgM and elevated serum aminotransferases. Chronic HAV infection is characterized by anti-HAV IgG.
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How can HAV infection be prevented?
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Active immunization with an attenuated vaccine or passive immunization with anti HAV IgG.
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In which season do most HAV infections occur?
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Autumn
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