Microbiology Chapter 20

Front 1

Salmonella
-Salmonella typhimurium

Back 1

caused many diseases
-through frogs, milk, tomatoes, peanut butter...

Front 2

Gram negative bacilli
- spore forming?
- habitats?
- pathogenicity?
- all have ____ on outer cell wall

Back 2

1. non spore forming
2. large intestines
(enteric), zoonotic, respiratory, soil, water
3.not all of them all pathogens
4.lipopolysaccharide -endotoxin

Front 3

Gram negative enterics and nosocomial infections

Back 3

half of them influence those infections

Front 4

Aerobie Gram negative nonenteric

Back 4

• Pseudomonas and Burkholderia – an environmental opportunistic pathogen
• Brucella and Francisella – zoonotic pathogens
• Bordetella and Legionella – mainly human pathogens
• Alcaligenes – opportunistic pathogen

Front 5

Pseudomonas have ___ flagella/um

Back 5

1 polar

Front 6

Pseudomonas are ...

Back 6

- free living
- bioremediators and decomposers
- main cause for contaminants in home or clinical setting
- respiration
- produce catalase and oxidase
- water soluble pigments

Front 7

Pseudomonas aeruginosa

Back 7

-in soild and water
- in intestine of 10% of human
- contminants of anethesia instruments, ventilators, IV solutions
- resistant to drying, medicines, ammnia disinfectant, soap
- opportunistic pathogen

Front 8

•Common cause of nosocomial infections in hosts with
burns, neoplastic disease, cystic fibrosis
• Complications include pneumonia, UTI, abscesses,
otitis, and corneal disease
• Endocarditis, meningitis, bronchopneumonia
• Grapelike odor
• Greenish‐blue pigment (pyocyanin)
• Strong multidrug resistant
• Cationic antimicrobial peptides
• PsrA‐ transcriptional regulator
upregulation resistance, biofilm,
rapid attachment , swarming motility
• Cephalosporins, aminoglycosides, carbenicillin,
polymixin, quinolones, and monobactams

Back 8

Pseudomonas aeruginosa

Front 9

• Genera Burkholderia, Acinetobacter,
Stenotrophomonas
• Similar to pseudomonads
• Wide variety of habitats in soil, water, and related
environments
• Obligate aerobes; do not ferment sugars
• Motile, oxidase positive
• Opportunistic

Back 9

Burkholderia, Acinetobacter,
Stenotrophomonas, pseudomonas

Front 10

-active in biodegradation
of a variety of substances; -opportunistic agent in
respiratory tract, urinary tract, and occasionally
skin infections; drug resistant

Back 10

Burkholderia cepacia

Front 11

via injury or inhalation
environmental reservoir; wound infections,
- bronchitis and pneumonia, septicemia

Back 11

B. pseudomallei

Front 12

- nosocomial and
community acquired infections;
- via wounds, lungs,
urinary tract, burns, blood; extremely resistant –>combination antimicrobials

Back 12

Acinetobacter baumanii

Front 13

- contaminant of disinfectants
dialysis equipment,
respiratory equipment,
water dispensers, and
catheters;
clinical isolate in
respiratory soft tissue,
blood ,CSF;
- biofilms
- resistant to multi medicines

Back 13

Stenotrophomonas maltophilia

Front 14

malta fever, undulant fever, and Bang
disease – a zoonosis transmitted to humans from
infected animals

Back 14

Brucellosis,

Front 15

• Fluctuating pattern of fever –weeks to a year
• Combination of tetracycline and rifampin or
streptomycin
• Animal vaccine available
• Potential bioweapon

Back 15

Brucella

Front 16

a zoonotic disease of mammals
endemic to the northern hemisphere, particularly
rabbits

Back 16

tularemia,

Front 17

Tularemia is transmitted by

Back 17

contact with infected animals, water
and dust or bites by vectors

Front 18

tularemia

Back 18

Headache, backache, fever, chills, malaise and
weakness
• 10% death rate in systemic and pulmonic forms
• Intracellular persistence can lead to relapse
• Gentamicin or tetracycline
• Attenuated vaccine
• Potential bioterrorism agent