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76 Cards in this Set

  • Front
  • Back
An organic nutrient essential to an organism's metabolism that cannot be synthesized itself is termed a

trace element
micronutrient
growth factor
mineral
growth factor
The source of the necessary elements of life is

an inorganic environmental reservoir
the sun
rocks
the air
an inorganic environmental reservoir
An organism that can synthesize all its required organic components from CO2 using energy from the sun is

photoautotroph
photoheterotroph
chemoautotroph
chemoheterotroph
photoautotroph
An obligate halophile requires high

pH
temperature
salt
pressure
salt
Chemoautotrophs can survive on ____ alone

minerals
CO2
minerals and CO2
methane
minerals and CO2
Which of the following substances are required by ALL organisms?

organic nutrients
inorganic nutrients
growth factors
oxygen gas
inorganic nutrients
A pathogen would most accurately be describe as a

parasite
commensal
saprobe
symbiont
parasite
Which of the following is true of passive transport?

it requires a gradient
it uses the cell wall
it includes endocytosis
it only moves water
it requires a gradient
A cell exposed to a hypertonic environment will _____ by osmosis

gain water
lose water
neither gain nor lose water
burst
lose water
Active transport of a substance across a membrane requires

a gradient
the expenditure of ATP
water
diffusion
the expenditure of ATP
Psychrophiles would be expected to grow

in hot springs
on the human body
at refrigeration temperatures
at low pH
at refrigeration temperatures
Which of the following is NOT involved in quorum sensing?

accumulation of inducer molecules
a certain level of biofilm density
self-monitoring
release of genetic material
release of genetic material
superoxide ion is toxic to strict anaerobes because they lack

catalase
peroxidase
dismutase
oxidase
dismutase
The time required for a cell to undergo binary fission is called the

exponential growth rate
growth curve
generation time
lag period
generation time
In a variable plate count, each ____ represents a ______ from the sample population.

cell, colony
colony, cell
hour, generation
cell, generation
colony, cell
The stage in population growth with the highest rate of cell division is the

stationary phase
lag phase
log phase
enlargement phase
log phase
A compound synthesized by bacteria or fungi that destroys or inhibits the growth of other microbes is a/an

synthetic drug
antibiotic
antimicrobial drug
competitive inhibitor
antibiotic
Which statement is NOT an aim in the use of drugs in antimicrobial chemotherapy? The drug should

have selective toxicity
be active even in high dilutions
be broken down and excreted rapidly
be microbial
be broken down and excreted rapidly
Microbial resistance to drugs is acquired through

conjugation
transformation
transduction
all of these
all of these: conjugation, transformation, & transduction
R factors are _______ that contain a code for __________

genes, replication
plasmids, drug resistance
transposons, interferon
plasmids, conjugation
plasmids, drug resistance
When a patient's immune system becomes reactive to a drug, this is an example of

superinfection
drug resistance
allergy
toxicity
allergy
An antibiotic that disrupts the normal flora can cause

the teeth to turn brown
aplastic anemia
a superinfection
hepatotoxicity
a superinfection
Most antihelminthic drugs function by

weakening the worms so they can be flushed out by the intestine
inhibiting worm metabolism
blocking the absorption of nutrients
inhibiting egg production
all of these
inhibiting worm metabolism
Select a drug/s that can prevent a viral nucleic acid from being replicated

axidothymidine
acyclovir
amantadine
both a and b
both axidothymidine and acyclovir
Which of the following modes of action would be most selectively toxic?

interrupting ribosomal function
dissolving the cell membrane
preventing cell wall synthesis
inhibiting DNA replication
preventing cell wall synthesis
Which of the following effects do antiviral drugs NOT have?

killing extracellular viruses
stopping virus synthesis
inhibiting virus maturation
blocking virus receptors
killing extracellular viruses
The MIC is the ___ of a drug that is required to inhibit growth of a microbe

largest concentration
standard dose
smallest concentration
lowest dilution
smallest concentration
An antimicrobial drug with a _______ therapeutic index is a better choice than one with a ____ therapeutic index

low, high
high, low
high, low
The best descriptive term for the resident microbes is

commensals
parasites
pathogens
contaminants
commensals
Resident microbiota is commonly found in the

liver
kidney
salivary glands
urethra
urethra
Normal resident microbes are absent from the

pharynx
lungs
intestine
hair follicles
lungs
Virulence factors include

toxins
enzymes
capsules
all of these
all of these
the specific action of hemolysins is to

damage white blood cells
cause fever
damage red blood cells
cause leukocytosis
damage red blood cells
The ____ is the time that lapses between encounter with a pathogen and the first symptoms

prodrome
period of invasion
period of convalescence
period of incubation
period of incubation
The presence of a few bacteria in the blood is termed

septicemia
toxemia
bacteremia
a secondary infection
bacteremia
A ____ infection is acquired in a hospital

subclinical
focal
nonsocomial
zoonosis
nonsocomial
A/an ______ is a passive animal transporter of pathogens

zoonosis
biological vector
mechanical vector
asymptomatic carrier
mechanical vector
An example of a noncommunicable infection is

measles
leprosy
tuberculosis
tetanus
tetanus
A general term that refers to an increased white blood cell count is

leukopenia
inflammation
leukocytosis
leukemia
leukocytosis
The occurrence of Lyme disease mainly in areas where certain species of ticks live would define it as a/an ____ disease
endemic
A positive antibody test for HIV would be a ________ of infection.

sign
symptom
syndrome
sequela
sign
Which of the following would NOT be a portal of entry

the meninges
the placenta
the skin
the small intestine
the meninges
Which of the following is not a condition of Koch's postulates?

isolate the causative agent of a disease
cultivate the microbe in a lab
inovulate a test animal to observe the disease
test the effects of a pathogen on humans
test the effects of a pathogen on humans
An outbreak would be endemic because

it happened over a wide geographic region
a rise in the number of cases over a short time
it was transmitted by a common vehicle
it occurred in all age groups
a rise in the number of cases over a short time
An example/s of a nonspecific chemical barrier to infection is/are

unbroken skin
lysozyme in saliva
cilia in respiratory tract
all of these
lysozyme in saliva
Which nonspecific host defense is associated with the trachea?

lacrimation
ciliary lining
desquamation
lactic acid
ciliary lining
Which of the following is not a lymphoid tissue?

spleen
thyroid gland
lymph node
GALT
thyroid gland
Which of the following blood cells function primarily as phagocytes?

eosinophils
basophils
lymphocytes
neutrophils
neutrophils
What is included in GALT?

thymus
Peyer's patches
tonsils
breast lymph nodes
Peyer's patches
A signaling molecule from microbes recognized by phagocytes is

pyrogen
PAMP
complement
lectin
PAMP
Monocytes are ____ leukocytes that develop into ______

granular, phagocytes
agranular, mast cells
agranular, macrophages
granular, T cells
agranular, macrophages
Which of the following inflammatory signs specifies pain?

tumor
dolor
calor
rubor
dolor
Toll-like receptors are proteins on ______

phagocytes that recognize foreign molecules
viruses that stimulate immune reactions
skin cells that provide barriers to infection
lymphocytes that damage parasitic worms
phagocytes that recognize foreign molecules
An example of an inflammatory mediator that stimulates casodilation is

histamine
collagen
complement C5a
interferon
histamine
_____ is an example of an inflammatory mediator that stimulates chemotaxis

endotoxin
serotonin
a fibrin clot
interleukin-2
a fibrin clot
An example of an exogenous pyrogen is

interleukin-1
complement
interferon
endotoxin
endotoxin
______ interferon, producted by T lymphocytes, activates cells called _____ and is involved in destroying viruses

gamma, fibroblasts
beta, lymphocytes
alpha, natural killer cells
beta, fibroblasts
alpha, natural killer cells
Which of the following substances is NOT producted by phagocytes to destroy engulfed microorganisms?

hydroxyl radical
superoxide anion
hydrogen peroxide
bradykinin
bradykinin
Which of the following is the end product of the complement system?

properdin
cascade reaction
membrane attack complex
complement factor C9
membrane attack complex
Which of these characteristics is not a major factor in adaptive or acquired immunity?

specificity
recognition
chemotaxis
memory
chemotaxis
The primary b-cell receptor is

IgD
IgA
IgE
IgG
IgD
In humans, B cells mature in the ______ and T cells mature in the
bone marrow, thymus
small, simple molecules are _____ antigens

poor
never
effective
mosaic
poor
Which type of cell actually secretes antibodies?

T cell
macrophage
plasma cell
monocyte
plasma cell
CD4 cells are ___ cells and CD 8 cells are ______ cells

killer, suppressor
helper, cytotoxic
cytotoxic, helper
B, T
helper, cytotoxic
Helper T cells receive antigen from ____ and cytotoxic cells receive antigen from _____
class II MHC, class I MHC [in this order]
The cross-linkage of antigens by antibodies is known as

opsonization
cross-reaction
agglutination
complement fixation
agglutination
The greatest concentration of antibodies is found in the ________ fraction of serum

gamma globulin
albumin
beta globulin
alpha globulin
gamma globulin
T ______ cells assist in the functions of certain B cells and other T cells

sensitized
cytotoxic
helper
natural killer
helper
cytotoxic T cells are important in controlling

virus infection
allergy
autoimmunity
all of these
virus infections
vaccination is synonymous with _____ immunity
artificial active
Which of the following can seve as antigen-presenting cells {APCs}?

T cells
B cells
macrophages
dendritic cells
all but T cells
all but T cells
A living microbe with reduced virulence that is used for vaccination is considered

a toxoid
attenuated
denatured
an adjuvant
attenuated
A vaccine that contains parts of viruses is called

acellular
recombinant
subunit
attenuated
subunit
widespread immunity that protects the population from the spread of disease is called

sero positivity
cross-reactivity
epidemic prophylaxis
herd immunity
herd immunity
DNA vaccines contain _______ DNA that stimulates cells to make _______ antigens

human, RNA
microbial, protein
human, protein
microbial, polysaccharide
microbial, protein