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44 Cards in this Set

  • Front
  • Back
Ferments mannitol, produces hemolysins and DNAase
Staphylococcus aureus
Diabetics and drug addicts have a much higher rate of colonization of this bacteria
Staphylococcus aureus
Epidemic outbreaks of this bacteria can be traced by several methods, including serological, phage typing, DNA fingerprinting, ribotyping, and DNA sequencing of selected genes such as protein A and coagulase among different strains
Staphylococcus aureus
This bacteria has a phage receptor that is useful for typing purposes in outbreaks
Staphylococcus aureus
This genus of bacteria is 60% resistant to methicillin
Staphylococci
This genus of bacteria is the major cause of hospital-related bacteremias in the US
Staphylococci
Toxin mediated disease of Staph. aureus that does not require colonization by the bacteria
Food poisoning (food borne diarrhea); contamination of food or tampon by toxin
Toxin mediated disease of Staph. aureus that requires colonization followed by toxin production
TSS, scalded-skin syndrome
This bacteria synthesizes multiple surface adhesive molecules that bind to the host cellular matrix proteins found on damaged skin, disrupted airway epithelium, or endothelial cell walls within the bloodstream (fibrinogen, fibronectin, colleage, platelets, etc.)
Staph. aureus
Cause of food poisoning by Staphylococcus aureus
Enterotoxins A through I, excluding F, of S. aureus (enterotoxin F is TSST-1)
This bacteria secretes numerous toxins and enzymes that can cause host cell lysis
Staph. aureus
Protein A
Cell wall protein found in S. aureus that binds to host IgG via the Fc receptor, inhibiting complement-mediated killing.
This is a B-cell superantigen that leads to defective production of specific IgM
Protein A
These are T-cell superantigens the blunt specific host T-cell response
Enterotoxins A through I, excluding F, of S. aureus (enterotoxin F is TSST-1)
This enzyme clots human or rabbit plasma by activating fibrinogen (by first activating thrombin)
Coagulase, found in Staphylococcus aureus
Eap (Map)
Surface protein of S. aureus that impairs neutrophil recruitment
Superantigens stimulate secretion of these cytokines
IL-1, IL-2, TNF
Mupirocin
Used intranasally to prevent nasal colonization of Staphylococcus aureus
T/F: Diarrhea caused by enterotoxin of S. aureus is often bloody
False. It causes nausea, vomiting and non-bloody diarrhea
EtaA, EtaB
Exfoliatin toxins secreted by phage group II S. aureus; the cause of SSSS
Phage group II Staphylococcus aureus
Cause scalded-skin syndrome
This disease is usually seen in infants, characterized by erythematous skin followed by peeling
Staphylococcal scalded-skin syndrome
This disease is commonly associated with tampon use, patients with wound infects, or patients with nasal packing
Toxic shock syndrome (Staph aureus)
Antibiotics are not helpful in these diseases because many of the syndromes are immunological
Toxin-mediated syndromes of Staph aureus
Deep-seated infections that can be caused by S aureus
Pneumonia, endocarditis, osteomyelitis, arthritis, abscess (liver, spleen, kidney, brain), meningitis, sepsis
This bacteria can cause hematogenous arthritis, especially in children
Staphylococcus aureus
Semisynthetic penicillin
Used to treat Staphylococcus aureus--penicillinase renders them resistant to regular penicillin but not synthetic penicillin
Dicloxacillin
Oral semisynthetic penicillin
Oxacillin
Intravenous semisynthetic penicillin
Coagulase negative Staphylococci
Epidermidis, saprophyticus
T/F: S. epidermidis forms white colonies that are larger than the colonies of S. aureus
False. Colonies are smaller.
This bacteria shows very little hemolysis on blood agar plate
Staphylococcus epidermidis
These bacteria can be distinguished from each other by testing for mannitol fermentation
Staphylococci. Only aureus ferments mannitol
These bacteria are notable for colonizing IV catheters
Staphylococci aurues and epidermidis
This bacteria can colonize prosthetic surfaces very efficiently
Staph epidermidis
This bacteria can proliferate and invade bloodstream, but much more slowly than Staph aureus
Staph epidermidis
Attachment of Staphylococcus epidermidis to synthetic surfaces (to form a biofilm) is mediated by this
Surface carbohydrates
This bacteria is resistant to semisynthestic penicillin; treat with vancomycin
Staph epidermidis
Clinical course of infection by this bacteria is generally indolent
Staph epidermidis (eg, infected prosthetic device)
These bacteria are distinguished from each other by resistance to novobiocin
Staphylococcus epidermidis and saprophyticus
This bacteria causes UTI's in young women, second only to E. coli
Staph saprophyticus
Treatment for S aureus infections
Semisynthetic penicillin; vancomycin as last resort
Treatment for S saprophyticus infections
Trimethoprim (Bactrim), quinolone (norfloxacin)
Treatment for S epidermidis infections
Vancomycin; if toxin, add rifampin and/or gentimicin