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5 Cards in this Set
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African trypanosomiasis (sleeping sickness)
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Trypanosoma brucei gambiense, T. b. rhodesiense (flagellates)
Tsetse fly (Glossina) Infx: Blood, lymphatics, CNS (TQ-extracellular) Sx: Winterbottom’s sign, fever, headache, increased IgM, Red painful Ulcer, Slurred Speech, Behavior change Lab: Trypanosomes in blood, lymph, CSF: culture, serologic tests |
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American trypanosomiasis (Chagas’ disease)
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Trypanosoma cruzi (flagellate)
Reduvid "kissing" bug Infx: Blood (extracellular); RES, heart, brain (TQ-intracellular) Ex: Romaña’s sign, fever, heapatosplenomegaly, myocarditis, meningoencephalitis Lab: Trypanosomes in blood,; culture, xenodiagnosis, biopsy, serologic tests |
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Visceral leishmaniasis (kala-azar)
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Leishmania donovani complex (flagellates)
Bite of infected sandfly Infx: Liver, spleen, lymph nodes, bone marrow (TQ-intracellular) Sx: Hepatosplenomegaly, anemia, fever, weight loss Lab: Parasites (Amistigotes) in smears and culture of bone marrow, hamster inoculation, serologic tests |
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Cutaneous leishmaniasis
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Leishmania tropica, L. mexicana, L. braziliensis complexes (flagellates)
Bite of infected sandfly Infx: Skin (TQ-intracellular) Sx: Skin ulcers (single of multiple; self-healing to incurable) Lab: Parasites in smears and culture of ulcer aspirate, serologic tests |
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Mucocutaneous leishmaniasis
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Leishmania braziliensis braziliensis (flagellate)
Bite of infected sandfly Infx: Skin and adjacent mucous membranes (TQ-intracellular) Sx: Ulcers of skin and oral and nasal mucosa, Edema Lab: Parasites in smears and culture of ulcer material, serologic tests |
