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46 Cards in this Set

  • Front
  • Back

Central nervous system

Brain and spinal cord

What do motor neurons do?

carry messages from CNS to parts of the body and cause them to respond

What do sensory neurons do?

transmit sensations to the CNS

Meninges

three layers of membranes cover surface of brain and spinal cord

Meningitis is caused by

bacteria that infect meninges of CNS

Pneumococcal Meningitis signs and symptoms

begins like mild cold


stiffness of neck

Pneumococcal meningitis causative agent

streptococcus pneumoniae


gram positive lancet-shaped coccus

Pneumococcal meningitis often causes

otitis media


(middle ear ache)

Purpose of serotypes

To get various strains/types

Meningococcal Meningitis is acquired by

inhaling airborne droplets and it goes into respiratory tract

Infants with Haemophilus influenzae meningitis have this

Bulging fontanelle which is a gap between plates of infant's skull

Most serious type of Haemophilus influenzae meningitis is

Type B; abbreviated Hib, causes most serious disease

Neonatal meningitis signs and symptoms

"floppy baby"


fever, poor feeding, lethargy

Causative agent of Neonatal meningitis

Listeria monocytogenes from bloodstream of infected mother

Listeriosis signs and symptoms

after one month


fever, muscle aches, diarrhea, nausea

Causative agent of listeriosis

Listeria monocytogenes (gram positive rod)

Source of meningeal infection

Bacteremia

Listeriosis results from

foodborne disease listeriosis

Hansen's disease signs and symptoms

1. gradual onset of pigmentation changes, increased or decreased sensation in areas of skin


2. Nerves of arms, legs may become visibly enlarged


3. Muscle wasting, ulceration, loss of fingers or toes


4. Severe cases: thickening of nose and ears, deep wrinkling of facial skin

Hansen's disease causative agent

Mycobacterium leprae, it is acid fast

Hansen's disease is the only known human pathogen that does what?

Preferentially infects peripheral nerves

Though Hansen's disease can ________ _________, the _____________ ___ _____________.

Stop spontaneously, the damage is permanent

Botulism

the progressive paralysis that involves all voluntary muscles

Causative agent for botulism

clostridium botulinum, produce different strains of neurotoxin


Endospores can survive boiling

How powerful is botulism?

A few miligrams could kill the population of a large city

Flaccid paralysis

limp/"rag doll"

Intestinal botulism occurs when

C. botulinum colonizes

Viral meningitis signs and symptoms

abrupt onset

Inflammatory response differs from bacterial meningitis because

fewer cells enter cerebrospinal fluid, causes little lasting damage

Leading cause of Viral encephalitis is

transmitted by mosquitoes

Early warning signs of viral encephalitis

blood of sentinel chickens in cages tested periodically

poliomyelitis acts like what?

Acts the same way as menigitis at first, but is not the same

Poliomyelitis signs and symptoms

respiratory muscles paralyzed


survivors may develop post-polio syndrom

Poliomyelitis pathogenesis

enters body orally

Poliomyelitis treatment and prevention

small risk led US to return to use of inactivated salk vaccine in 1999

How can rabies be diagnosed before death?

By identifying virus in smears collected from surface of eyes

Cryptococcal Meningoencephalitis progresses faster in

immunodeficient

causative agent for cryptococcal meningoencphalitis

Cryptococcus neoformans


causes disease even in healthy individuals

Cryptococcal meningoencephalitis treatment and prevention

There is no good anti fungal drugs


monitored carefully for toxic effects

African sleeping sickness signs and symptoms

loss of interest, decreased activity, indifference to food

African sleeping sickness is transmitted by

tsetse flies; protozoan enters bite wound in saliva of infected tsetse fly

Primary Amebig Meningoencephalitis (PAM) once neurological symptoms appear

death follows quickly

causative agent of PAM

naegleria fowleri (one of only a few free-living protozoa pathogenic for humans


will eat your brain

PAM pathogenesis

Penetrates skull along olfactory nerves of nasal mucosa

Where is PAM found?

commonly found in warm, fresh water and soils




not found in sea water or pools

TSE, kuru, is linked to

cannibalism in New Guinea