Micro Bio Exam Ii Last Lecture

Front 1

What kinds of categories are animal viruses classified into?
4 categories.

Back 1

DNA viruses, +/- ss RNA, DS RNA or RNA containing retroviruses

Front 2

LIfe cycle of an animal / enveloped virus:

Back 2

Attachment: sites on viral capsid/evenelop spikes attach to receptors of animal cell
Penetration: Animal cell engulfs endocytosis, entire virion
Uncoating: separation of nucleic acid from protein coat liberates the nucleic acid into the host cell

Front 3

Animal virus uncoating

Back 3

separation of nucleic acid from protein coat liberates the nucleic acid into the cell

Front 4

Penetration of animal virus

Back 4

Endocytosis.

Front 5

DNA viruses how do they carry their genome?

Back 5

As double stranded DNA

Front 6

5 DNA viruses:

Back 6

Herpesviridae
Papoviridae
Adenoviridae
Poxviridae
Hepadnaviridae

Front 7

Papoviridae

Back 7

genital and somatic warts
cancers on females reproductive system

Front 8

Herpesviridae

Back 8

include genital and oral herpes chickenpox infectious mono

Front 9

Adenoviridae

Back 9

common cold

Front 10

Poxviridae

Back 10

smallpox

Front 11

Hepadnaviridae

Back 11

Hepatitis B

Front 12

Double stranded DNA viral life cycle

Back 12

DNA travels to nucleus
Early genes make viral enzymes
Late genes Viral DNA replicated
Late translation synthesizes capsid proteins.
Capsid proteins migrae into the nucelus, where maturation occurs and virions are constructed.
Viral particles are released out the ER via budding.
at least 5 passages across the envelope

Front 13

+ strand

Back 13

is the sense coding strand and makes sense because it looks like mRNA

Front 14

- strand

Back 14

template strand antisense, complementary to the mRNA

Front 15

Picornaviridae:

Back 15

ss RNA + strand poliovirus

Front 16

Rhabdoviridae

Back 16

ss RNA virus (-) rabies virus

Front 17

Retroviridae

Back 17

large group of RNA viruses carrying ss (+) RNA that carry out life cycles using enzyme reverse transcriptase. HIV

Front 18

Togaviridae:

Back 18

RNA virus encephalitis yellow fever and rubella (German measles)

Front 19

Flaviviridae

Back 19

west nile fever

Front 20

Filoviridae

Back 20

Ebola fever.

Front 21

Hepadnaviridae

Back 21

Hepatitis B

Front 22

Double stranded DNA viral life cycle

Back 22

DNA travels to nucleus
Early genes make viral enzymes
Late genes Viral DNA replicated
Late translation synthesizes capsid proteins.
Capsid proteins migrae into the nucelus, where maturation occurs and virions are constructed.
Viral particles are released out the ER via budding.
at least 5 passages across the envelope

Front 23

+ strand

Back 23

is the sense coding strand and makes sense because it looks like mRNA

Front 24

- strand

Back 24

template strand antisense, complementary to the mRNA

Front 25

Picornaviridae:

Back 25

ss RNA + strand poliovirus

Front 26

Rhabdoviridae

Back 26

ss RNA virus (-) rabies virus

Front 27

Retroviridae

Back 27

large group of RNA viruses carrying ss (+) RNA that carry out life cycles using enzyme reverse transcriptase. HIV

Front 28

Togaviridae:

Back 28

RNA virus encephalitis yellow fever and rubella (German measles)

Front 29

Flaviviridae

Back 29

west nile fever

Front 30

Filoviridae

Back 30

Ebola fever.

Front 31

Orthomyxoviridae

Back 31

influenza flu

Front 32

paramyxoviridae

Back 32

mumps and measles

Front 33

S.S (+) RNA viral life cycle

Back 33

they have (+) that acts directly as mRNA in cytoplasm and make RDRP
RDRP make (-) that makes more (+) strands.
capsid proteins are made and eventually packed into mature virions as the ss (+) genome RNA. buddout

Front 34

SS (-) RNA viral life cycle

Back 34

They CONTAIN RDRP which immediately makes (-) that transcribes (+).
the (+) serve as template to make more (-) strands.
and make more capsid proteins and RDRP. the new (-) strands are packaged into ss (-) RNA genome, along with the enw RDRP. buddout

Front 35

Retroviral life cycle

Back 35

usually (=) strands RNA and have enzyme reverse transcriptase RNA dependent DNA polymerase.
the ss (+) serves as template to make ds DNA which migrates to the nucleus
The DNA integrates into a host cell and is now a provirus that never leaves.
The (+) can be transcribed to make more viral proteins including reverse transcriptaese, the (+) strands also act as the genome to make new virions.

Front 36

Cancer oncogenic viruses
how do they cause cancer?
2 examples

Back 36

usually DNA or Retro because they enter nucleus and can't cause if they didn't
HTLV and FeLV
HPV ect.