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58 Cards in this Set

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when does the blastocyst implant into the endometrium
2nd week post fetilization
what does the embryoblast develop into?
embryo proper
what are cytotrophoblasts connected by?
desmosomes
decidual cells are derived from?
endometrial stroma
what is this?
large, high lipid/glyc content, pas positive, protect blastocyst from immune reaction, secrete prosta's and prolactin
decidual cells
when does the blastocyst implant into the endometrium
2nd week post fetilization
what does the embryoblast develop into?
embryo proper
what are cytotrophoblasts connected by?
desmosomes
decidual cells are derived from?
endometrial stroma
what is this?
large, high lipid/glyc content, pas positive, protect blastocyst from immune reaction, secrete prosta's and prolactin
decidual cells
endometrium located between the myometrium and the chorion frondosum, contributes to placenta
decidua basalis
endometrium located between the embryo and the uterine lumen
decidua capsularis
remainder of uterine endometrium on the wall opposite the implantation site
decidua parietalis
where is the chorion derived from?
trophoblast
villous of feathery part of chorion adjacent to decidua basalis(contributes to placents)
chorion frondosum
smooth part of chorion adjacent to the decidua capsularis
chorion laeve
maternal blood flows through spaces in the chorion and is in direct contact with the cells of the chorion. This is called?
hemochorial placenta, note however that there is a complete seperation of maternal and fetal blood
when are the primary, secondary and tertiary villi formed?
primary - 11-13 days post ovulation
secondary - 16 days
tertiary - 3rd week and beyond
what is the core of a secondary villi made of?
mesenchyme from the mesoderm
what does the placental barrier include when it's thick? when it's thin?
syncyciotrophoblast, *discontinuous cytotrophoblast, trophoblast basal lamina, *CT, fetal caps basal lamina, fetal cap endothelium
fused with the decidua basalis, attach anchoring villi, outer covering of the fetal part of placenta, interrupted by maternal blood vessels
cytotrophoblast shell part of the chorion frondosum
fetal side of the placenta, large branches of umbilical arteries and veins of fetal circulation
chorionic plate
what are the two sides of the chorionic plate?
smooth amniotic cells, cyto and syncytiotrophoblast
where do stem villi arise from?
the chorionic plate
what are the names of villi that branch from the sides of stem villi and dont fuse w/ decidua basalis
free, terminal or branch villi
formed by decidual partitions that grow into the maternal blood space
cotyedons
how many cotyledons in one placenta
15-25
what cells produce acidophilic PAS pos material called fibrinoid?
decidual cells (found under cotlyedons heading)
where do spiral arteries of the mother empty into?
intervillous space, blood flows to the chorionic plate initially represented by the lacunae of the syncycio
in the fetus, where does poorly oxygenated blood flow from? and what does it flow through?
flows from fetus to placents through paired umbilical arteries
in fetus, where does highly oxygenated blood flow from? what does it flow through
flows from palcenta to fetus through a single umbilical vein
what does the umbilical cord become covered by?
the amnion(simple cuboidal epithelium)
contain main branches from the umbiical arteries and veins, branch repeatedly, which increases SA for metobolic exchange
stem villi
how can anchoring villi mix maternal blood?
anchoring villi contract to mix maternal blood
bathed by maternal blood in intervillous spaces
tertiary villi
aggregates of syncytiotrophoblast nuclei
syncytial knots, may break off and enter maternal circulation
sparse microvilli, no terminal web, actin near cell surface, mito w/ both tubular and shelf cristae, lipid droplets, multivesicular bodies, share basement membrane with some of the fetal capillaries
syncytial cells of the tertiary villi, have properties of absorptive cells, protein and steroid secreting cells
macrophages located in the core of the tertiary villous are called?
hofbauer cells
what cells are mainly responsible for absorption in teh placenta?
syncytio
what Ig_ can cross the placenta?
IgG
what cells mainly produce glycogen, cholesterol and fatty acids(metabolites) and steroid hormones (estrogen/progesterone)
syncytio
maintains pregnancy, precursor is from the fetal adrenal cortex
estrogen
maintains pregnancy, placenta takes over its production from the corpus luteum
progesterone
maintains corpus luteum, especially during early pregnancy, homologous to TSH in stimulating maternal thyroid to produce T4,
hCG
growth promoting and lactogenic hormone, other name hPL(human placental lactogen), regulates glucose metabolism,
hCS
what hormone stimulates mammary duct proliferation
hCS
where is hCS produced?
the syncytio
when does hCG production begin?
around day 6 of pregnancy
what is produced by and stimulates the proliferation of the cytotrophoblast?
IGF-I and IGF-II
maintains the function of the differentiated trophoblast
endothelial growth factor
where is endothelial growth factor produced?
early - cytotrophoblasts,
later - syncyciotrophoblasts
contributes to softening of the cervix/pelvic ligaments,
relaxin
what cells produce relaxin?
decidual cells
regulates maternal nutrient storage relative to the requirements of the fetus
leptin
where is leptin produced?
the syncyciotrophoblast
stiumulates the prolifertion of breast tissue and milk production
prolactin
where is prolactine produced?
produced by decidual cells
involved in the initiation of partutition, produced by decidual cells
prostaglandins