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14 Cards in this Set

  • Front
  • Back
When should you admit someone with acute HF
severely decompensated HF with: hypotension, worsening renal funciton, altered mentation

dyspnea at rest

hemodynamically significant arrhythmia - including new onset of rapid Afib

ACS
What are the common vasodilators used in HF?

and what are their MOAs, half life and what are the most useful in?
IV Nitro - venodilator, arteriodilator at higher doses.. Half-life 3-5 min useful in patients with HF and MI

Nitroprusside - potent, balanced veno and arteriodilator. Half-life 2 min useful in severe HTN or severe valvular regurgitation. Need art-line

nesiritide - greater decrease in PCWP than NTG but no impact on dyspnea
what are the 4 hemodynamic/clinical states of acute HF
dry and warm
dry and col
wet and warmwet and cold
What are the signs of low perfusion?
cool extremities
low urine output
altered mental status
inadequate response to IV diuretics
prerenal azotemia
What are the signs of congestion?
high JVP
hepatojugular reflux
peripheral edema
S3
SOBOE
rales
recent weight gain
pathophys of ACHF
low CO
elevated filling pressures - elevated PCWP, elevated RA pressure
elevated SVR
What is the problem and soultion for dry and warm HF?
De nada.

Stable HF
What is the problem and solution for wet and warm HF?
volume overloaded, but preserved forward flow
diurese, diurese, diurese - often as easy as increasing vasodilators
what do you do if the patient with wet and warm HF fails to respond to diuretics?
INCREASE DIURETICS
fluid restrict
continuous diuretic infusion
addition of second tpye of diuretic
ultrafiltration

IV vasodilators useful in pulmonary edema and severe hypertension (don't use if there is symptomatic hypotension)
What is the problem and solution for wet and cold HF?
low CO and high filling pressures

treatment - diuresis and increase vasodilators
IV inotropes are used when there is low EF and low output syndrome with:
marginal BP <90
unresponsive to vasodilators
poor response to diuretics
worsening renal function
What is the problem and solution for dry and cold HF?
usually don't get admitted unless end-stage
usually didn't start that way but were made that way by our interventions
vasodilators if BP ok
inotropes if low BP
heart transplant indications
persistently severely symptomatic HF irrespective of LVEF once other causes of dyspnea are ruled out
-frequent hospitalizations
-arrhythmic complications
-cardiorenal
absence of contraindications
poor one-year survival
failure to respond to maximal medical/device therapy
heart transplant contraindications
primary systemic disease that may limit survival
- hepatic, pulmonary, or medical renal disease
active infection
documented noncompliance
drug/EtOH abuse (3 months abstinence)
active cancer
DM with end organ damage
significant cerebral vascular disease or PVD
obesity/cachexia
Options for IV ionotropes

their MOA
dobutamine - Beta1/2 agonist (3:1) causes mild arterial vasodilatation. Causes tachycardia

milrinone - causes vasodilatation, may cause severe and sustained hypotension

dopamine - stimulates beta, alpha and dopaminergic receptors. Causes tachycardia. Good choice when inotropy and vasodilatation needed