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117 Cards in this Set

  • Front
  • Back
What are the general desired qualities of the nurse/therapist/clinician?
o Most important quality: Communication
o Genuineness/authenticity: ability to be honest with Pt (Pt will be able to risk being more genuine themselves)
o Empathy: ability to understand and share the feelings of others (vs Sympathetic: condolence, agreement, pity)
o Compassionate neutrality, unconditional regard (for the Pt)
o Self reflective: → ↑ ability to empathize w/ Pt
o Respect for the patient: the Pt is an individual who deserves respect
Discuss the difference between social vs therapeutic communication?
o Social communication is less formal than therapeutic, so therapeutic is more appropriate in mental health milieu
o The Pt is the focus of the communication with therapeutic communication
What are the phases of the Nurse-Patient relationship?
1. Pre-Orientation/Pre-Interaction Phase
2. Orientation/Introductory Phase
3. Working Phase: (note: a ↓ working phase → ↓ depth of relationship w/ Pt)
4. Termination Phase
What does the pre-orienation and pre-interaction phase consist of?
- Gathering data about Pt (haven’t assessed Pt yet, so from ED, chart, written/oral reports, family/EMT/police)
- Self-reflection: ID own feelings; plan for first contact w/ Pt
What does the orientation/introductory phase consist of?
- Emphases: build trust, assess, ID Pt’s emotions, provide support, establish structure
- Establish contact and create environment conducive to trust and rapport
- Establish mutually-agreeable goals and own plan of action (care plans are vital to Tx of psych. Pt’s)
- ID Pt’s strengths and weaknesses
- Establish length of relationship (it’s OK to ID self as student and note that interactions will be max of 96 hours)
- Formulate nursing diagnoses
What does the working phase consist of?
- ID, explore, link, and modify behaviors, thoughts, attitudes relative to presenting issue(s)
- Establish short- and long-term goals (might be change or stabilization vs. “cure”)
- Solve problems
- Address resistance (Freudian: part of us that resists Δ)
- Exploring/Journaling/Confrontation: these help Pt to note reactions to events to help w/ their care; try not to
direct Pt, but help them come to realizations
- Redefining perceptions & interpretations with goal of more realistic conclusions
- Promoting Δ (Pt-initiated)
What does the termination phase consist of?
- therapeutic closure to relationship
- Reason(s): e.g.: d/c of Pt; end of nursing rotation
- Difficult phase, may try to avoid
- Review: goals met, + Δ’s, strategies for coping w/ future crises
- Referrals: MD, therapist
- ID resources for future needs of Pt
- D/C instructions: nurse is responsible for summarizing for the Pt the d/c instructions from several sources
- “Official good-bye”; encourage future therapeutic relationships and friendships
What is transference?
Pt reacting to clinician as if they were someone else
What is countertransference?
clinician transferring unconscious emotion onto the Pt
What information is in a Mental Status Exam/Evaluation?
o ID Data (e.g. name, age, S/O, occupation, religion, med. Dx’s, allergies, CC)
o Gen’l Description (appearance, grooming, dress, ht/wt, scars/tattoos, hair, motor activites, speech, gen’l attitude)
o Emotions (mood [subjective], affect [objective], appropriateness)
o Thought Processes (content of thought [how words are spoken] vs. form of thought [how words are assembled])
o Perceptual Disturbances (hallucinations, illusions, depersonalization, derealization)
o Sensorium and Cognitive Ability (A&O, memory, capacity for abstract thought, fund of knowledge)
o Impulse Control (r/t hostility, guilt, affection, sexuality)
o Judgment and Insight (solve problems, make decisions, knowledge of self, coping strategies)
o All terms discussed in conjunction with a mental status evaluation
What is the purpose of Mini-Mental Status evaluation?
for eval of organic problems if not enough time to perform complete Mental Status Exam
What is the general information about the DSM-IV, such as what diagnoses might be found on Axis I, for example, the
main diagnoses that we’ve discussed class?
o Axis I Psychiatric, clinical syndromes: acute problems – problem is treated successfully and Pt is released
Note: no one can be admitted to psych dept. without an Axis I condition
o Axis II Personality Disorders and Mental Retardation: chronic / ongoing problems
o Axis III Medical Diagnoses: e.g. COPD, HF, DM; whether or not r/t psych. Problem
Note: Dx’s such as wrist lac’s, ↓ mentation, etc. should be recognized as possibly r/t psych. problems
o Axis IV Stressors
o Axis V Global Assessment of Functioning (GAF)
Examples of Axis I (“Parity Diagnoses”: covered by insurance the same as medical issues; “non-parity” Dx’s also):
Major Depression … Bipolar Disorder … Schizophrenia … Schizoaffective … PTSD … OCD … Anxiety Disorder
What is Axis I?
Psychiatric, clinical syndromes: acute problems – problem is treated successfully and Pt is released
Note: no one can be admitted to psych dept. without an Axis I condition

Examples of Axis I (“Parity Diagnoses”: covered by insurance the same as medical issues; “non-parity” Dx’s also):
Major Depression … Bipolar Disorder … Schizophrenia … Schizoaffective … PTSD … OCD … Anxiety Disorder
What is Axis II?
Personality Disorders and Mental Retardation: chronic / ongoing problems
What is Axis III?
Medical Diagnoses: e.g. COPD, HF, DM; whether or not r/t psych. Problem
Note: Dx’s such as wrist lac’s, ↓ mentation, etc. should be recognized as possibly r/t psych. problems
What is Axis IV?
Stressors
What is Axis V?
Global Assessment of Functioning (GAF)
What is the purpose of a defense mechanism?
Primary function is to reduce anxiety and to protect the ego
What are defense mechanisms?
Defense mechanisms are psychological strategies to cope with reality and maintain self-image
What is repression (involuntary) as a defense mechanism?
involuntary exclusion of a painful or conflictual thought, impulse, or memory from
awareness. Performed by ego as attempt to allow for ~normal functioning
What is suppression (voluntary) as a defense mechanism?
Being vaguely aware of the thought or feeling but try to hide it
What is sublimation as a defense mechanism?
Redirecting a feeling into a socially productive activity
What is reaction formation as a defense mechanism?
Turn a feeling into its opposite (overcompensation for unacceptable impulses)
What is displacement as a defense mechanism?
Redirecting feelings to another target; discharging feelings on people less dangerous
than who aroused the emotion
What is intellectualization as a defense mechanism?
Dealing with emotional conflict through excessive use of abstract thinking or making
generalizations (more intellectualized type of rationalization)
What is devaluation as a defense mechanism?
Dealing with conflict by attributing exaggerated negative qualities to self or others
What is idealization as a defense mechanism?
Overestimation of desirable qualities / underestimation of limitations (of desired object
or person)
What is rationalization as a defense mechanism?
Various explanations to justify a situation while denying feelings
What is projection as a defense mechanism?
Thinking someone else has your thoughts or feelings
What is passive aggression as a defense mechanism?
Dealing with conflict by indirectly and unassertively expressing aggression
What is regression as a defense mechanism?
Reverting to an old (usually immature) behavior to ventilate feelings
What is compensation as a defense mechanism?
Encountering failure of frustration in some activity and overemphasizing another activity
What is denial as a defense mechanism?
Completely rejecting a thought or feeling
What are the general concepts regarding all forms of Brief Therapy?
o Future-focused, goal-directed: focuses on solutions & recovery, rather than problem that brought client to therapy
o Used in diverse fields of practice: business, social policy, education, criminal justice systems, child welfare
o Optimistic assumption – Pt has strengths and abilities, resources and skills that they bring with them
• may not be in touch with these
o Client is expert regarding their own difficulty/problem
o Attempt to reconnect Pt’s with their own intrinsic abilities: client has ability to get well; just guide and help them
o Change is inevitable and client wants change
o Identify what is already working; Pt may already have solutions to problem & may simple need confidence boost
o Understanding past not necessary to develop possibility for future
o Keep concepts / solutions simple and meaningful
• complex problems don’t always need complex solutions” (Steve de Shazer)
What is positive reinforcement and give an example?
Adding favorable event after desired behavior

Rewarding a child who gets good grades
What is negative reinforcement and give an example?
Removing unfavorable event after desired behavior

Noise stopped when rat hits correct lever
What is positive punishment and give an example?
Adding unfavorable event after undesired behavior

Time out (for toddlers)
What is negative punishment and give an example?
Removing favorable event after undesired behavior

Withholding privileges after misbehavior
What is extinction and give an example?
Ignoring behavior

Ignoring a tantrum
What is response cost?
Weaken a behavior by removing positive stimulus

(similar to negative punishment)
What is reciprocal inhibition and give an example?
Inhibit one response by the occurrence of another incompatible response

Conditioning a relaxation response to stimuli that used to provoke anxiety
What is systematic desensitization and give an example?
Less-to-more distressing stimuli to desensitive to feared situation (ends w/ In Vivo exposure)

Pt w/ fear of heights gradually being exposed to higher and higher places
What is flooding and give an example?
Accelerated systematic desensitization

Pt w/ fear of heights taken to top floor 1st
What is the definition of overgeneralization from cognitive therapy?
Drawing conclusions about a wide variety of things based on one event
What is the definition of arbitrary inferences from cognitive therapy?
Making a negative conclusion about something without supporting evidence
What is the definition of selective abstraction from cognitive therapy?
Forming conclusions based on an isolated detail of an event; other information is ignored and
the significance of the total context is missed
What is the definition of magnification/minimization from cognitive therapy?
Perceiving a case or situation in a greater or lesser light than it truly deserves
(exaggerating or trivializing)
What is the definition of personalization from cognitive therapy?
Tendency to relate external events to oneself, even when no basis for making a connection
What is the definition of catastrophizing from cognitive therapy?
Thinking worst-case scenario will be outcome for all situations
What is the definition of Dichotomous (Polarized) Thinking from cognitive therapy?
Thinking in extremes, that things are either all good or all bad
What is the definition of perfectionism from cognitive therapy?
Needing to do everything perfectly to feel good about oneself
What is the definition of mind reading from cognitive therapy?
Believing that one knows the thought of another without validation
What is the definition of externalization of self-worth from cognitive therapy?
Self-determining one’s value based on the approval of others
What are the basic functions of lobes of the brain connected to psychiatric symptoms (frontal lobe)?
primary and supplemental motor, eye movement, language, cognition, personality, social judgment,
attention, volition
What are the basic functions of lobes of the brain connected to psychiatric symptoms (parietal lobe)?
sensation, taste, reading, writing, facilitates spatial orientation
What are the basic functions of lobes of the brain connected to psychiatric symptoms (temporal lobe)?
hearing, sense of smell, speech center (language comprehension), emotions, memory
What are the basic functions of lobes of the brain connected to psychiatric symptoms (occipital lobe)?
visual discrimination, some aspects of visual memory
What are the basic functions of lobes of the brain connected to psychiatric symptoms (limbic system)?
(instincts, drives, needs and emotions)
o Amygdala – regulates emotional responses – misfiring of neurons here may be involved in Bipolar
• Overstim of amygdala r/t PTSD
o Thalamus – filters incoming information regarding emotions, moods and memories
o Hypothalamus – eating, temperature regulation, emotion, autonomics, water balance, circadian rhythm,
pituitary function
o Hippocampus – major role in encoding, consolidation, and retrieval of memories
What neurotransmitters are involved with schizophrenia?
• ↑ DA in limbic system → + s/s of schizophrenia
• ↓ DA in frontal cortex → – s/s of schizophrenia
o Serotonin blocked by atypical antipsychotics in cortical areas liberates DA ;
liberated DA alleviates – s/s of schizophrenia (e.g. ↑ DA → negative s/s)
What neurotransmitters are involved with depression?
↓ serotonin and ↓ NE
What neurotransmitters are involved with mania?
↑ serotonin and ↑ NE
What neurotransmitters are involved with anxiety?
↑ NE and ↓ GABA
What neurotransmitters are involved with Alzheimer's?
↓ ACh
What are the positive symptoms of schizophrenia?
o Positive (r/t ↑ DA; excess or distortion of normal function)
• Hallucinations
• Delusions
• Formal Thought Disorder
What are the negative symptoms of schizophrenia?
• Decreased eye contact
• Decline in grooming and hygiene
• Flattened affective responses
• Thought blocking
• Inattentiveness
• Diminished volition (avolition – ↓motivation . . . to get out and participate in life)
• Decreased expressive gestures
• Diminished recreational interests
• Decrease in relationships (tend to be isolative)
• Diminished content speech – poverty of thought
• Knowledge/cognitive deficits
What is the etiology of schizophrenia – how much genetic, how much cultural, how much family dynamics?
• Biologic theories
- Biochemical: Dopamine – too much in some parts of brain; not enough in others
• Neurostructural
- Changes in ventricular brain ratios
- Brain Atrophy
- ↓ Blood Flow in Pre-Frontal Cortex
• Genetic (10% of 1st-degree relatives of schizophrenia get it)
• Perinatal Risk Factors: flu epidemics → % schizophrenia in offspring of mothers who had the flu
What are the risk factors of schizophrenia?
• 46% lifetime risk if identical twin has schizophrenia
• 10% lifetime risk if sibling has schizophrenia
o Lasts a lifetime for 95%
• 1/3 of all homeless have schizophrenia
• 20-50% attempt suicide, 10% (?) completed suicide (probably higher)
• 20% shorter life expectancy (r/t less inclination to seek help from family friends, healthcare)
What are some common nursing dx for Schizophrenia?
 Altered Thought Process (most common)
 Impaired communication
 Self-care Deficits
 Activity Intolerance
 Social Isolation
 Decisional Conflict
 Disturbed Sensory Perception
 Disturbed Body Image
 Excess Fluid Volume (r/t excess fluid intake/water intoxication → hyponatremia)
 Disturbed Thought Process
 Dysfunctional Family Processes
 Interrupted Family Processes
What are some nursing interventions for Schizophrenia?
 Preventing relapse
 Promoting adequate communication
 Promoting adherence to medication regimen
 Assisting with grooming and hygiene
 Promoting organized behavior
 Promoting social interaction and activity
 Promoting social skills and activities
 Intervening with hallucinations and delusions
 Promoting congruent emotional responses
 Promoting family understanding and involvement
 Promoting community contacts
Describe the 1st generation of antipsychotic medications?
Completely block D2 receptors
greater impact on + symptoms (which are r/t ↑ DA)
Significant side effects
Examples: Thorazine (Chlorpromazine), Haldol (Haloperidol)
Absorption rate: 1-6 hours
Tranquilization begins in 1 hour
Half life: 10-30 hours
Continued improvement for 6-8 weeks
Accumulate in fatty tissues; highly protein bound
Metabolized by cytochrome P450 system in liver
Describe the 2nd generation of antipsychotic medications?
Weak blocking of D2; strong blocking of D1 and D4
Blocks 5HT2 serotonin receptors; serotonin inhibits DA, so serotonin → ↑ DA in cortical region of brain
Greater impact on + symptoms (r/t ↑ DA) but treat – symptoms and cognitive s/s
↓ EPSE compared with 1st gen
↑ risk of metabolic changes: diabetes, weight gain, hyperlipidemia
Examples: Clozaril, Riperdal, Zyprexa, Seroquel, Geodon, Abilify
Many 2nd Gen’s used across diagnostic categories (e.g., Zyprexa as a mood stabilizer)
What are the possible side effects of antipsychotic medications?
• Anticholinergic side effects
o Dry mouth, blurred vision, constipation, urinary retention
• Salivation (esp. w/ Clozaril) (even though most side effects are anticholinergic)
• Nausea/GI upset (recommend taking with food)
• Rash
• Sedation
• Orthostatic Hypotension
• Photosensitivity
• Hormonal
o Decreased libido
o Amenorrhea
o Weight Gain
• Reduction of Seizure Threshold
• Extrapyramidal (EPSEs)
o Akathisia
o Akinesia
o Dystonia
o Tardive Dyskinesia
What will extrapyramidal (EPSEs) look like in your patient?
Extrapyramidal (EPSEs) – r/t blockage of D2 receptors in mid-brain (i.e. not enough DA)
o Pseudoparkinsonism
- Tremor, shuffling, drooling, pill-rolling, rigidity
- Good response to anticholinergics (e.g. Benadryl, Cogentin, Artane)
What will akathisia look like in your patient?
o Akathisia (continuous restlessness and fidgeting – very uncomfortable to the Pt)
- Restless legs, jittery feelings
- Occurs early in treatment
- Differentiate from agitation
- Poor response to anticholinergics
What will akinesia look like in your patient?
o Akinesia
- Slowed movements (bradykinesia) or absence of movement
- Weakness
- Fatigue or no energy
- Responds to anticholinergics
What will dystonia look like in your patient?
o Dystonia
- Involuntary muscular movements of face, arms, legs, and neck
- Abnormal sustained contracted postures
- Appears early in tx
- Responds to anticholinergics
- Oculogyric crisis may occur: uncontrolled rolling back of the eyes (unable to see; can be painful)
What will tardive dyskinesia look like in your patient?
o Tardive Dyskinesia
- Bizarre facial and tongue movements (lip smacking, teeth grinding, tongue thrusting or writhing), stiff
neck, difficulty swallowing
- Occurs after long term use of antipsychotics (long-term use of antipsychotics → damage)
- Symptoms stop with sleep, worsen with anticholinergics (i.e. ↑ tardive dyskinesia with Benadryl)
- Assess using AIMS (abnormal involuntary movement scale) – pp. 856-857 in text
- May be irreversible
- Treatment (attempt): change antipsychotic medications (no anticholinergics – worsen s/sx)
What are special considerations with a patient taking clozaril (clozapine)?
agranulocytosis: CBC’s to monitor WBCs
What are special considerations with a patient taking thorazine (chlorpromazine) & Haldol (haloperidol)?
aplastic anemia (pancytopenia): CBCs to monitor RBC/WBC/platelets
Renally excreted: monitor BUN/creatinine for ↓ renal sufficiency
What are special considerations with a patient taking risperdal (risperidone)?
Do not take with cola or tea (coffee OK)
What is Neuroleptic Malignant Syndrome (NMS)?
NMS is a complete blockage of DA and can → death
What are special considerations with a patient taking seroquel (quetiapine)?
Risk of DM – monitor for s/sx
CNS depression → ↓ thirst response: monitor for dehydration
What symptoms might the patient exhibit Neuroleptic Malignant Syndrome?
severe parkinsonian muscle rigidity, hyperpyrexia (107° +), tachycardia, tachypnea, fluctuations in BP,
diaphoresis, deterioration of mental status to stupor and coma
What actions might you take as the nurse with a patient exhibiting signs of possible Neuroleptic Malignant Syndrome?
o Treat with DA agonists (Dantrolene or Bromocriptine)
o Treat s/sx with cooling blankets and antipyretics (e.g. ibuprofen)
What medications are used to treat side effects of antipsychotics?
 Anticholinergic (dryness, constipation): [ n/a re: med’s ] encourage fluid intake and use of stool softeners
 EPSEs: anticholinergics (Cogentin, Benadryl, Artane) to ↓ DA breakdown (i.e. ↑DA), buspirone (BuSpar – an
axiolytic) for two weeks prior to start of antipsychotics
What are the symptoms of major depression?
• Depressed mood for more than 2 weeks
• Loss of interest in pleasurable activities
• Impaired social functioning
• Change in appetite/weight
• Change in sleep / fatigue
• Sense of worthlessness, thoughts of death
• Decreased concentration
What are the risk factors of major depression?
gender (women twice as likely), divorce, age (20 – 50 first time; > 65), prev. episode, heredity
What are some Nursing Dx for major depression?
• Risk for Self-Directed Violence
• Situational/Chronic Low Self-Esteem
• Hopelessness
• Ineffective Coping
What are some nursing interventions for major depression?
• Preventing suicide/promoting safety
• Promoting self-esteem
• Instilling hope
• Enhancing socialization
• Medications
• ECT
What are some Psychobiologic treatments other than meds to treat major depression?
• Symptom alleviation (not necessarily eliminating root cause)
• Therapy/ies (individual, group, family, cognitive
• Teaching (coping strategies)
• ECT
What medication might be used to help a patient stop smoking?
o Nicotine replacement therapy (patch, lozenge, gum, inhaler) – ↓ cravings by maintaining blood nicotine
o Bupropion (Zyban) – antidepressant that assists with smoking abstenance
o Welbutrin
What might an ER/ED do for a patient who is suspected of overdosing on an opiate?
Naloxone (Narcan): fast-acting opioid antagonist to counteract respiratory depression
What do you need to educate your patient about using Antabuse (disulfiram)?
No alcohol in any form (watch cough syrups, cough drops, mouthwashes)
How is withdrawal from alcohol most commonly treated?
 Early detection
 Monitor fluid status (can be overhydrated or dehydrated)
 Magnesium sulfate to ↓ irritability and prevent seizures
 Vitamins (alcohol interferes with absorption of B vitamins)
 Benzos to prevent Dts
 Disulfiram (Antabuse) or natrexone (ReVia, Trexan)
What are symptoms of alcohol withdrawal?
 Minor withdrawal (onset 6-12 hours; duration 48-72 hours):
• early – anxiety, agitation, irritabity
• later – tremor, tachycardia, HTN, diaphoresis, hallucinations
 Major withdrawal (Dts; onset 2-3 days; duration 3-5 days):
• ↑ temp, tachycardia, HTN, severe diaphoresis
How would you know that someone has developed tolerance to alcohol?
Tolerance is a reduction in receptor sensitivity, so an ↑ amount of alcohol req’d to intoxicate
Blood alcohol levels – what’s the legal level in Colorado?
 DUI: > 0.08%
 DWAI: > 0.05% (0.02% for < 21 yoa)
What are medications used for bipolar?
-antipsychotics
-antidepressants
-mood stabilizers
How are antipsychotics used to treat bipolar?
Antipsychotics (for hyperactive and agitated behavior)
(used when starting lithium to control s/sx since lithium takes 1-3 weeks to become effective)
• risperidone (Risperdal)
• olanzapine (Zyprexa)
How and what antidepressants are used to treat bipolar?
Antidepressants (during depressive swings)
• TCAs, MAOIs, SSRIs
How and what mood stabilizers are used to treat bipolar?
 Lithium
• Li helps stabilize K+ and Na+ to reduce over-excitement at cellular level
• blood levels indicating therapeutic vs toxic levels
- therapeutic range: 0.8 – 1.4 mEq/L
- toxic at 1.5 – 2 mEq/L
• side effects r/t toxic levels (no known antidote, so Tx is lavage and dialysis)
- tremors (persist throughout therapy)
- N/V/D (probably subside if taken with food)
- thirst (probably subside with adequate fluids)
- confusion
- blurred vision
- hypotension (fluid imbalance r/t K+ and Na+ imbalances)
- arrhythmias (interrupted cardiac activity r/t K+ and Na+ imbalances)
• nursing implications, such as water and salt intake
- teach Pt to eat a normal diet with normal salt intake and maintain adequate fluid intake (2.5 L/day)
- assess for renal function, cardiovascular disease
- remind women to use contraception
- warn Pt re: side effects
 Anticonvulsants (e.g. valproic acid)
• seem to work off-label
• Side effects: sedation, tremor, depression, psychosis, weakness; N/V/D, indigestion, cramps,
constipation; ~↑ AST/ALT/LDH/bilirubin
What are the SE of lithium?
- tremors (persist throughout therapy)
- N/V/D (probably subside if taken with food)
- thirst (probably subside with adequate fluids)
- confusion
- blurred vision
- hypotension (fluid imbalance r/t K+ and Na+ imbalances)
- arrhythmias (interrupted cardiac activity r/t K+ and Na+ imbalances)
What are the nursing implications for lithium?
nursing implications, such as water and salt intake
- teach Pt to eat a normal diet with normal salt intake and maintain adequate fluid intake (2.5 L/day)
- assess for renal function, cardiovascular disease
- remind women to use contraception
- warn Pt re: side effects
What are the symptoms of a manic episode of someone with bipolar disorder?
o Symptoms of a manic episode (persistent expansive mood for > 1 week)
• may or may not have psychotic features (altered realities)
• inflated self esteem, grandiose
• ↓ need for sleep; constant motor activity
• pressured speech; flight of ideas
• racing thoughts
• easily distracted
• expansive involvement in pleasure-seeking activities … to the expense of well-being (money, social, physical)
What are nursing interventions for bipolar disorder?
• Promote client safety: provide safe env., monitor activities, set and enforce limits
• Administer medications: antipsychotics, lithium carbonate
• Promote reality-based thinking
• Enhance socialization
• Promote self-care
• Enhance rest and sleep
What are the symptoms that someone is suicidal?
they tell you; depression, hopelessness, helplessness, hostility, anger, guarded, tense, worried, labile;
impulsive change in appearance, write a will, say “good-bye,” give away possessions, begin using substances;
withdraw from friends, loses interest in activities, preoccupied with death and dying
What are the risk factors of someone who is suicidal?
older white male, or younger black male; unemployed; ↑ stressors; possession of weapon; family
history; prior suicide attempt; significant illness; current or former psychiatric Pt; alcoholic
What might you ask or
what action might you take to assess the pt’s risk and help increase the pt’s safety?
o What you might ask: Do they have a plan and will they it to you? Have they figured out ways to keep someone
from stopping them?
o What action you might take: offer hope that alternatives are available (don’t offer glib reassurance); remove
weapons; get help (ER, 911, National Hopeline Network)
What population is most at risk for suicide?
Non-hispanic white men >= 65 yoa
What are the symptoms and patient education for Serotonin Storm or Serotonin Syndrome?
 Symptoms: agitation, ↑ BP, ↑ temp
 Patient education: watch medication combinations that ↑ serotonin levels
What are the symptoms and patient education for Serotonin Discontinuation Syndrome?
 Symptoms: dizziness, fatigue, light-headedness, anxiety, nausea, HA, ↑ aggression, ↓ mood
 Patient education: Taper down SSRIs (vs. abrupt stop)
What do you need to educate your patient about taking MAOIs?
Watch intake of tyramine (e.g. in foods such as aged cheeses). Tyramine is a NE agonist; can → hypertensive crisis
Must wait 5 weeks between SSRIs and MAOIs or ↑ risk of hypertensive crisis
What do you need to educate your patient about taking Tricyclics?
May not like side effects
What do you need to educate your patients about taking SSRIs?
If going to start on another antidepressant, should not do it right away
Discuss SSRIs used for antidepressants?
SSRIs
Action: Prevents reabsorption of serotonin → ↑ serotonin in synaptic cleft
Medications: Celexa, Prozac, Luvox, Paxil, Zoloft
S/Es: GI upset, sexual dysfunction, HA, Serotonin Syndrome
Discuss TCAs used for antidepressants?
Action: Block reuptake of serotonin and norepinephrine (but also block other receptors)
Medications: Elavil, Norpramin, Sinequan, Tofranil, Vivactil, Ludiomil
SEs: anticholinergic side effects: dry mouth, wt gain, sedation,
hypotension, dizznes, cardiac
Discuss MAOIs used for antidepressants?
MAOIs
Action: Inhibits metabolizing enzyme of serotonin and NE
Medications: Nardil, Marplan, Parnate
SEs: lightheadedness, drowsiness,
insomnia, stiff/sore neck,
palpations, N/V, flushing,
nose bleeds