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14 Cards in this Set
- Front
- Back
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Acute (Post Streptococcal) Glumerulonephritis |
- deposition of immune complexes on the glomerular membranes -more common in children and young adults following respiratory infections with Streprococcus pyelogines |
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Rapidly Progressive (Crescentric) Glomerulonephritis |
-deposition of immune complexes in the glomerular membrane due to systemic immunologic disorder or complication of other forms of glomerular nephritis |
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Goodpasture's Syndrome |
Cytotoxic antibody: antiglomerular basement membrane antibody is formed after a viral respiratory infection which attaches to the membrane of the glomerulus and lungs, activating the complement, causing capillary distruction |
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Vasculitis: Wegener's Granulomatosis |
Autoantibody: antineutrophilic cytoplasmic antibody attaches to the neutrophils in the vascular walls, causing damage to the small blood vessels of the kidney and lungs which results to granulomas formation |
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Vasculitis: Henoch-Schoenlein Purpura |
affects children after a respiratory infection causing decrease in platelets, affecting vascular integrity |
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Membranous Glomerulonephritis |
thickening of the glomarular membrane following IgG immune complex deposition due to systemic disorders: Sjoren Hepa B 2° Syphilis gold/mercury treatment and malignancy |
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Membranous proliferative glomerulonephritis |
cellular proliferation affecting the peripheral capillaries and/or glomarular basement membrane possibly due to immune reactions |
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Chronic glomerulonephritis |
marked decrease in renal function resulting from glomerular damage due to other renal disorders |
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IgA Nephropathy (Berger Disease) |
common in children and young adults deposition of IgA on the glomerular membrane due to increased serum IgA levels; may be caused by a mucosal infection |
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Nephrotic syndrome |
disruption of the shield of negativity and damage to the tightly fitting podocyte barrier, resulting in massive loss of proteins and lipids |
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Minimal Change Disease (Lipid nephrosis) |
disruption of the podocytes occuring primarily in children unknown etiology but associated with allergic reactions, immunization, and HLA-B12 |
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Focal Segmental Glomerulosclerosis |
diruption of podocytes in certain areas of glomeruli associated with HIV/AIDS, heroine and analgesic abuse
usual immune deposits: IgM, C3 |
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Alport Syndrome |
uncommon, mostly affects males
genetic disorder of collagen production causing lamellated and thinning of the glomerular membrane |
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Diabetic Nephropathy |
complication of diabetes mellitus
1. glycosylated proteins attach glomerular membrane 2. increase proliferation of mesangial cells 3. increase deposition of cellular and noncellular material within bowman's capsule and tuft |
