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3 Cards in this Set

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  • Back

Paracetamol

500mg to 1g po


4-6 hrs


Max 4g


Can cause hepatotoxicity

Nsaids moa

Inhibits cox 1 and cox 2


Cox enz are derived from arachidonic acid and produce prostaglandin


Cox 1 - renal perfusion, plt aggregation, gastroprotection


Cox 2 - pain, fever, inflammation, inhibits plt aggreg


Nsaids are cox inhibitors

Nsaids nonselective nz

Ibuprofen 1200mg max/day. Short term and acute acting


Naproxen 1000mg max/day. Long acting for chronic pain


Diclofenac but has more cox 2 inhibition so avoid