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484 Cards in this Set

  • Front
  • Back
ankyl/o
crooked or stiff
arthr/o

articul/o
joint
(articulation)
brachi/o
arm
cervic/o
neck
chondr/o
cartilage
(gristle)
cost/o
rib
crani/o
skull
dactyl/o
digit
(finger or toe)
fasci/o
fascia
(a band)
femor/o
femur
fibr/o
fiber
kyph/o
humpback
lei/o
smooth
lord/o
bent
lumb/o
loin (lower back)
myel/o
bone marrow or spinal cord
my/o

myos/o

muscul/o
muscle
oste/o
bone
patell/o
knee cap
pelv/i

pelv/o
hip bone or pelvic cavity
radi/o
radius
rhabd/o
rod shaped or striated (skeletal)
sarc/o
flesh
scoli/o
twisted
spondyl/o

vertebr/o
vertebra
stern/o
sternum
(breastbone)
ten/o

tend/o

tendin/o
tendon
(to stretch)
thorac/o
chest
ton/o
tone or tension
uln/o
ulna
appendicular skeleton
bones of shoulder, pelvis & upper & lower extremities
axial skeleton
bones of skull, vertebral column, chest & hyoid bone (U-shaped bone lying @ the base of the tongue)
bone
specialized connective tissue composed of osteocytes (bone cells) forming the skeleton
compact bone
tightly solid, strong bone tissue resistant to bending
spongy (cancellous) bone
mesh-like bone tissue containing marrow & fine branching canals through which blood vessels run
long bones
bones of arms & legs
short bones
bones of wrists & ankles
flat bones
bones of ribs, shoulder blades, pelvis & skull
irregular bones
bones of vertebrae & face
sesamoid bones
round bones found near joints
(e.g. patella)
epiphysis
wide ends of a long bone
(physis = growth)
diaphysis
shaft of a long bone
metaphysis
growth zone b/w epiphysis & diaphysis during development of a long bone
endosteum
membrane lining the medullary cavity of a bone
medullary cavity
cavity within the shaft of the long bones filled with bone marrow
bone marrow
soft connective tissue within the medullary cavities of bones
red bone marrow
found in cavities of most bones in infants; functions in formation of red blood cells, some white blood cells, & platelets; in adults, red bone marrow is found most often in the flat bones
yellow bone marrow
gradually replaces red bone marrow in adult bones, functions as storage for fat tissue, & is inactive in formation of blood cells
periosteum
a fibrous, vascular membrane that covers the bone
articular cartilage
a gristle-like substance found on bones where they articulate
articulation
a joint; the point where two bones come together
bursa
a fibrous sac b/w certain tendons & bones that is lined w/ a synovial membrane that secretes synovial fluid
disk (disc)
a flat, plate-like structure composed of fibrocarilaginous tissue found b/w the vertebrae to reduce friction
nucleus pulpsus
the soft, fibrocartilaginous, central portion of intervertebral disk
ligament
a flexible band of fibrous tissue that connects bone to bone
synovial membrane
membrane lining the capsule of a joint
synovial fluid
lubricating fluid secreted by the synovial membrane
muscle
tissue composed of fibers that can contract, causing movement of an organ or part of the body
striated (skeletal) muscle
voluntary striated muscle attached to the skeleton
smooth muscle
involuntary muscle found in internal organs
cardiac muscle
muscle of the heart
origin of a muscle
muscle end attached to the bone that does not move when the muscle contracts
insertion of a muscle
muscle end attached to the bone that moves when the muscle contracts
tendon
a band of fibrous tissue that connects muscle to bone
fascia
a band or sheet of fibrous connective tissue that covers, supports, & separates muscle
coronal (frontal) plane
vertical division of the body into front (anterior) back (posterior) portions
sagittal plane
vertical division of the body into RT & LT portions
transverse plane
horizontal division of the body into upper & lower portions
anterior (A)
front of the body
posterior (P)
back of the body
anterior-posterior (AP)
from front to back; commonly associated with the direction of an x-ray beam
posterior-anterior (PA)
from back to front; commonly associated with the direction of an x-ray beam
superior
situated above another structure, toward the head
inferior
situated below another structure, away from the head
proximal
toward the beginning or origin of a structure
distal
away from the beginning or origin of a structure
medial
toward the middle (midline)
lateral
toward the side
axis
line that runs through the center of the body or a body part
erect
normal standing position
decubitus
lying down, especially in bed
prone
lying face down & flat
recumbent
lying down
supine
horizontal recumbent; lying lying flat on the back- "on the spine"
flexion
bending at the joint so that the angle b/w the bones is decreased
extension
straightening @ the joint so that the angle b/w the bones is increased
abduction
movement away from the body
adduction
movement toward the body
rotation
circular movement around an axis
eversion
turning outward
inversion
turning inward
supination
turning upward or forward of the palmar surface (palm of the hand) or plantar surface (sole of the foot)
pronation
turning downward or backward of the palmar surface (palm of the hand) or plantar surface (sole of the foot)
dorsiflexion
bending the foot or the toes upward
plantar flexion
bending the sole of the foot by curling the toes toward the ground
range of motion (ROM)
total motion possible in a joint, described by the terms related to body movements, i.e., ability to flex, extend, abduct, or adduct; measured in degrees
goniometer
instrument used to measure joint angles (gonio = angle)
arthralgia
joint pain
atrophy
shrinking of tissue such as muscle
crepitation

crepitus
grating sound made by movement of some joints or broken bones
exostosis
a projection arising from a bone that develops form cartilage
flaccid
flabby, relaxed, or having defective or absent muscle tone
hypertrophy
increase in the size of tissue such as muscle
hypotonia
reduced muscle tone or tension
myalgia

myodynia
muscle pain
ostealgia

osteodyia
bone pain
rigor

or

rigidity
stiffness; stiff muscle
spasm
drawing in; involuntary contraction of muscle
spastic
uncontrolled contractions of skeletal muscles causing stiff & awkward movements (resembles spasm)
tetany
tension; prolonged, continuous muscle contractions
tremor
shaking rhythmic muscular movement
ankylosis
stiff joint condition
arthritis
inflammation of the joints characterized by pain, swelling, redness, warmth, and limitation of motion- there are more than 100 different types of arthritis
osteoarthritis (OA)
most common form of arthritis that especially affects weight-bearing joints (e.g., knee, hip); characterized by the erosion of articular cartilage
rheumatoid arthritis (RA)
most crippling form of arthritis characterized by a chronic, systemic inflammation most often affecting joints & synovial membranes (especially in the hands & feet) causing ankylosis (stiff joints) and deformity
gouty arthritis
acute attacks of arthritis usually in a single joint (especially the great toe) caused by hyperuricemia (an excessive level of uric acid in the blood)
bony necrosis

sequestrum
dead bone tissue from loss of blood supply such as can occur after a fracture (sequestrum = something laid aside)
bunion
swelling of the joint @ the base of the great toe caused by inflammation of the bursa
carpal tunnel syndrome
condition that results from compression of the median nerve within the carpal tunnel at the wrist, characterized by pain, numbness, and tingling in the wrist and fingers by a weak grip; commonly seen as a result of cumulative trauma of surrounding tendons
chondromalacia
softening of cartilage
epiphysitis
inflammation of epiphyseal regions of the long bone
fracture (Fx)
a broken or cracked bone
closed fracture
a broken bone with no open wound
open fracture
compound fracture; a broken bone with an open wound
simple fracture
a nondisplaced fracture that requires manipulation or surgery to repair
complex fracture
a displaced fracture that requires manipulation or surgery to repair
fracture line
line made by broken bone
(e.g., oblique, spiral, or transverse)
comminuted fracture
broken in many little pieces
greenstick fracture
bending & incomplete break of a bone-most often seen in children
herniated disk or disc
protrustion of a degenerated or fragmented intervertebral disk so that the nucleus pulposus protrudes, causing compression on the nerve root
myeloma
bone marrow tumor
myositis
inflammation of muscle
myoma
muscle tumor
leiomyoma
smooth muscle tumor
leiomyosarcoma
malignant smooth muscle tumor
rhabdomyoma
skeletal muscle tumor
rhabdomyosarcoma
malignant skeletal muscle tumor
muscular dystrophy
a category of genetically transmitted diseases characterized by progressive atrophy of skeletal muscles (Duchenne's type is most common)
osteoma
bone tumor
osteosarcoma
type of malignant bone tumor
osteomalacia
disease marked by softening of the bone caused by calcium & vitamin D deficiency
rickets
osteomalacia in children (causes bone deformity)
osteomyelitis
infection of bone & bone marrow causing inflammation
osteoporosis
condition of decreased bone density & increased porosity, causing bones to become brittle & liable to fracture (porosis = passage)
spinal curvatures
kyphosis

lordosis

scoliosis
kyphosis
abnormal posterior curvature of the thoracic spine
(humpback condition)
lordosis
abnormal anterior curvature of the lumbar spine
(sway-back condition)
scoliosis
abnormal lateral curvature of the spine (S-shaped curve)
spondylolisthesis
forward slipping of a lumbar vertebra (listhesis = slipping)
spondylosis
stiff, immobile condition of vertebrae due to joint degeneration
sprain
injury to a ligament caused by joint trauma but without joint dislocation or fracture
subluxation
a partial dislocation
(luxation = dislocation)
tendinitis

tendonitis
inflammation of a tendon
electromyogram (EMG)
a neuroduagnostic graphic record of the electrical activity of muscle @ rest & during contraction to diagnose neuromusculoskeletal disorders (e.g., muscular dystrophy); usually performed by a neurologist
magnetic resonance imagining
(MRI)
a nonionizing imaging technique using magnetic fields & radiofrequency waves
nuclear medicine
ionizing imaging technique using radioactive isotopes
bone scan
radionuclide image of bone tissue to detect tumor, malignancy, etc.
radiography
x-ray imagingl an ionizing technique commonly used in orthopedics to visualize the extremities, ribs, back, shoulders, joints, etc.
arthrogram
an x-ray of a joint taken after injection of a contrast medium
diskogram
an x-ray of an intervertebral disk after injection of a contrast medium
dual-energy x-ray absorptiometry (DEXA)
an x-ray scan that measures bone mineral density of the spine & extremities to diagnose osteoporosis, determine fracture risk, & monitor treatment; classifications of the bone mass include normal, osteopenic, or osteoporotic as indicated by a T score (amount of bone mass of the patient compared to that of a normal young adult)
computed tomography (CT)

computed axial tomography (CAT)
a specialized x-ray procedure producing a series of cross-sectional images that are processed by a computer into a 2-dimensional or 3-dimensional image
sonography
ultrasound imaging; a nonionizing technique useful in orthopedics to visualize muscles, ligaments, displacements, & dislocations or to guide a therapeutic intervention such as that performed during arthroscopy
amputation
partial or complete removal of a limb; AKA, above-knee amputation; BKA, below-knee amputation
arthrocentesis
puncture for aspiration of a joint
arthrodesis
binding or fusing of joint surfaces
arthroplasty
repair or reconstruction of a joint
arthroscopy
procedure using an arthroscope to examine, diagnose, & repair a joint from within
bone grafting
transplantation of a piece of bone from one site to another to repair a skeletal defect
bursectomy
excision of a bursa
myoplasty
repair of muscle
open reduction, internal fixation (ORIF) of a fracture
internal surgical repair of a fracture by bringing bones back into alignment & fixing them into place, often utilizing plates, screws, pins, etc.
osteoplasty
repair of bone
osteotomy
an incision into bone
spondylosyndesis
spinal fusion
tenotomy
division by incision of a tendon to repair a deformity caused by shortening of a muscle
closed reduction, external fixation of a fracture
external manipulation of a fracture to regain alignment along with application of an external device to protect & hold the bone in place while healing
casting
use of a stiff, solid dressing around a limb or other body part to immobilize it during healing
splinting
use of a rigid device to immobilize or restrain a broken bone or injured body part; provide less support than a cast, but can be adjusted easier to accommodate for swelling from an injury
traction (Tx)
application of a pulling force to a fractured bone or dislocated joint to maintain proper position during healing
closed reduction, percutaneous fixation of a fracture
external manipulation of a fracture to regain alignment, followed by insertion of one or more pins through the skin to maintain position-often includes use of an external device called a fixator to keep the fracture immobilized during healing
orthosis
use of an orthopedic appliance to maintain a bone's position or provide limb support (e.g., back, knee, or wrist brace)
physical therapy (PT)
treatment to rehabilitate patients disabled by illness or injury, involving many different modalities (methods), such as exercise, hydrotherapy, diathermy, & ultrasound
prosthesis
an artificial replacement for a diseased or missing body part such as a hip, joint or limb
analgesic
a drug that relieves pain
narcotic
a potent analgesic that has addictive properties
anti-inflammatory
a drug that reduces inflammation
antipyretic
a drug that relieves fever
nonsteroidal anti-inflammatory drug (NSAID)
a group of drugs with analgesic, anti-inflammatory, & antipyretic properties (e.g., ibuprofen, aspirin) commonly used to treat arthritis
angi/o

vas/o

vascul/o
vessel
aort/o
aorta
arteri/o
artery
ather/o
fatty (lipid) paste
atri/o
atrium
cardi/o
heart
coron/o
circle or crown
my/o
muscle
pector/o

steth/o
chest
sphygm/o
pulse
thrombo
clot
ven/o

phleb/o
vein
varic/o
swollen, twisted vein
ventricul/o
ventricle (belly or pouch)
atrium
upper RT & LT chambers of the heart
endocardium
membrane lining the cavities of the heart
epicardium
membrane forming the outer layer of the heart
interatrial septum
partition b/t RT & LT atrium
interventricular septum
partition b/w RT & LT ventricle
myocardium
heart muscle
pericardium
protective sac enclosing the heart composed of 2 layers w/ fluid b/w
parietal pericardium
outer layer
(parietal = pertaining to wall)
pericardial cavity
fluid-filled cavity b/w the pericardial layers
visceral pericardium
layer closest to the heart
(visceral = pertaining to organ)
ventricle
lower RT & LT chambers of the heart
heart valves
structures within the heart that open & close with the heartbeat to regulate the one-way flow of blood
aortic valve
heart valve b/w the LT ventricle & the aorta
mitral or bicuspid valve
heart valve b/w the LT atrium & LT ventricle
(cuspis = point)
pulmonary semilunar valvue
heart valve opening from the RT ventricle to the pulmonary artery (luna = moon)
tricuspid valve
valve b/w the RT atrium & the RT ventricle
valves of the veins
valves located @ intervals within the lining of veins, especially in the legs, which constrict with muscle action to move the blood returning to the heart
arteries
vessels that carry blood from the heart to the arterioles
aorta
large artery that is the main trunk of the arterial system branching from the LT ventricle
arterioles
small vessels that receive blood from the arteries
capillaries
tiny vessels that join arterioles & venules
venules
small vessels that gather blood from the capillaries into the veins
veins
vessels that carry blood to the heart from the venules
systemic circulation
circulation of blood throughout the body through arteries, arterioles, capillaries, & veins to deliver oxygen & nutrients to body tissues
coronary circulation
circulation of blood through the coronary blood vessels to deliver oxygen & nutrients to the heart muscle tissue
pulmonary circulation
circulation of blood from the pulmonary artery through the vessels in the lungs & back to the heart via the pulmonary vein, providing for the exhange of gases
diastole
to expand; period in the cardiac cycle when blood enters the relaxed ventricles from the atria
systole
to contract; period in the cardiac cycle when the heart is in contraction & blood is ejected through the aorta & pulmonary artery
normotension
normal blood pressure
hypotension
low blood pressure
hypertension
high blood pressure
sinoatrial node (SA node)
the pacemaker; higher specialized neurological tissue, embedded in the wall of the RT atrium, responsible for initiating electrical conduction of the heartbeat, causing the atria to contract and firing conduction of impulses to the AV node
atrioventricular node
neurological tissue in the center of the heart that receives & amplifies the conduction of impulses from the SA node to the bundle of His
bundle of His
neurological fibers, extending from the AV node to the RT & LT bundle branches, that fire the impulse from the AV node to the Purkinje fibers
Purkinje fibers (network)
fibers in the ventricles that transmit impulses to the RT & LT ventricles, causing them to contract
polarization
resting; resting state of myocardial cell
depolarization
change of a myocardial cell from a polarized (resting) state to a state of contraction ( de = not; polarization = resting)
repolarization
recharging of the myocardial cell from a contracted state back to a resting state (re = again; polarization = resting)
normal sinus rhythm (NSR)
regular rhythm of the heart cycle stimulated by the SA node (average of 60 to 100 beats/minute)
arteriosclerosis
thickening, loss of elasticity, & calcification (hardening) of the arterial walls
atherosclerosis
buildup of fatty substances within the walls of arteries
atheromatous plaque
a swollen area within the lining of an artery caused by the buildup of fat (lipids)
thrombus
a stationary blood clot
embolus
a clot (e.g., air, fat, foreign object) carried in the bloodstream that obstructs when it lodges (embolus = a stopper)
stenosis
condition of narrowing of a part
constriction
compression of a part
occlusion
plugging; obstruction or a closing off
ischemia
to hold back blood; decreased blood flow to tissue caused by constriction or occlusion of a blood vessel
perfusion deficit
a lack of flow through a blood vessel caused by narrowing, occlusion, etc.
infarct
to stuff; a localized area of necrosis (condition of tissue death) caused by ischemia as a result of occlusion of a blood vessel
angina pectoris
chest caused by a temporary loss of oxygenated blood to heart muscle often caused by narrowing of the coronary arteries (angina = to choke)
aneurysm
a widening; bulging of the wall of the heart, the aorta, or an artery caused by congenital defect or acquired weakness
saccular
a sac-like bulge on one side
fusiform
a spindle-shaped bulge
dissecting
a split or tear of the vessel wall
claudication
to limp; pain in a limb (especially the calf) while walking that subsides after rest; it is caused by inadequate blood supply
diaphoresis
profuse sweating
heart murmur
an abnormal sound from the heart produced by defects in the chambers or valves
palpitation
subjective experience of pounding, skipping, or racing heartbeats
vegetation
to grow; an abnormal growth of tissues around a valve, generally a result of an infection such as bacterial endocarditis
arrythmia

dysrthythmia
any of several kinds of irregularity or loss of rhythm of the heartbeat
bradycardia
slow heart rate (<60 beats/minute)
fibrillation
chaotic, irregular contractions of the heart, as in atrial or ventricular fibrillation
flutter
extremely rapid but regular contractions of the heart, as in atrial or ventricular flutter (typically from 250-350 beats/minute)
heart block
an interference with the normal electrical conduction of the heart defined by the location of the block (e.g., AV block)
premature ventricular contraction (PVC)
a ventricular contraction preceding the normal impulse initiated by the SA node (pacemaker)
tachycardia
fast heart rate (>100 beats/minute)
arteriosclerotic heart disease (ASHD)
a degenerative condition of the arteries characterized by thickening of the inner lining, loss of electricity, & susceptibility to rupture- seen most often in the aged or smokers
bacterial endocarditis
a bacterial inflammation that affects the endocardium or the heart valves
cardiac tamponade
compression of the heart produced by the accumulation of fluid in the pericardial sac as results from pericarditis or trauma, causing rupture of a blood vessel within the heart (tampon = a plug)
cardiomyopathy
a general term for disease of the heart muscle
congenital anomaly of the heart
malformations of the heart present @ birth (anomaly = irregularity)
atrial septal defect (ASD)
an opening in the septum separating the atria
coarctation of the aorta
narrowing of the descending portion of the aorta resulting in a limited flow of blood to the lower part of the body
patent ductus arteriosus (PDA)
an abnormal opening between the pulmonary artery & the aorta caused by the failure of the fetal ductus arteriosus to close after birth (patent = open)
tetralogy of Fallot
an anomaly that consists of four defects: pulmonary stenosis, ventricular septal defect, malposition of the aorta, & RT ventricular hypertrophy-causes blood to bypass the pulmonary circulation so that deoxygenated blood goes into the systemic circulation, resulting in cyanosis (tetra = four)
ventricular septal defect (VSD)
an opening in the septum separating the ventricles
congestive heart failure (CHF)

LT ventricular failure
failure of the LT ventricle to pump an adequate amount of blood to meet the demands of the body, resulting in a "bottleneck" of congestion in the lungs that may extend to the veins, causing edema in lower portions of the body
cor pulmonale

RT ventricular failure
a condition of enlargement of the RT ventricle as a result of chronic disease within the pulmonary circulation & resistance of blood flow to the lungs (cor = heart)
coronary artery disease (CAD)
a condition affecting arteries of the heart that reduces the flow of blood & delivery of exygen & nutrients to the myocardium-most often caused by atherosclerosis
hypertension (HTN)
persistently high blood pressure
essential (primary) hypertension
high blood pressure attributed to no single cause, but risks include smoking, obesity, increased salt intake, hypercholesterolemia, & hereditary factors
secondary hypertension
high blood pressure caused by the effects of another disease (e.g., kidney disease)
mitral valve prolapse (MVP)
protrusion of one or both cusps of the mitral valve back into the LT atrium during ventricular contraction, resulting in incomplete closure & backflow of blood
myocardial infarction (MI)
heart attack; death of myocardial tissue (infarction) owing to loss of blood flow (ischemia) as a result of an occlusion (plugging) of a coronary artery- usually caused by atherosclerosis; symptoms include pain in the chest or upper body (shoulders, neck, & jaw) shortness of breath, diaphoresis, & nausea
myocarditis
inflammation of the myocardium most often caused by viral or bacterial infection
pericarditis
inflammation of the pericardium
phlebitis
inflammation of a vein
rheumatic heart disease
damage to heart muscle & heart valves by rheumatic fever (a streptococcal infection)
thrombophlebitis
inflammation of a vein associated with a clot formation
varicose veins
abnormally swollen, twisted veins with defective valves, most often seen in the legs
deep vein thrombosis (DVT)
formation of a clot in a deep vein of the body, occurring most often in the femoral & iliac veins
auscultation
a physical examination method of listening to sounds within the body with the aid of a stethoscope (e.g., auscultation of the chest for heart & lung sounds)
bruit
noise; an abnormal heart sound caused by turbulence within
gallop
an abnormal heart sound that mimics the gait of a horse; related to abnormal ventricular contraction
electrocardiogram (ECG or EKG)
an electrical picture of the heart represented by positive & negative deflections on a graph labeled with the letters P, Q, R, S, & T, corresponding to events of the cardiac cycle
stress electrocardiogram
an ECG of the heart recorded during the induction of controlled physical exercise using a treadmill or ergometer (bicycle); useful in detecting conditions such as ischemia & infaraction
Holter ambulatory monitor
a portable electrocardiograph worn by the patient that monitors electrical activity of the heart over 24 hours-useful in detecting periodic abnormalities
intracardiac electrophysiological study (EPS)
invasive procedure involving placement of catheter-guided electrodes within the heart to evaluate & map the electrical conduction of cardiac arrhythmias; intracardiac catheter ablation may be performed @ the same time to treat the arrhythmia
intracardiac catheter ablation
use of radiofrequency waves sent through a catheter within the heart to treat arrhythmias by selectively destroying myocardial tissue @ sites generating abnormal electrical pathways
magnetic resonance angiography (MRA)
magnetic resonance imaging of the heart & blood vessels for evaluation of pathology
nuclear medicine imaging of the heart
radionuclide organ imaging of the heart after administration of radioactive isotopes to visualize structures & analyze functions
myocardial radionuclide perfusion scan
a scan of the heart made after an intravenous injection of an isotope (e.g., thallium) that is absorbed by myocardial cells in proportion to blood flow throughout the heart
myocardial radionuclide perfusion stress scan
a nuclear scan of the heart taken after the induction of controlled physical exercise via treadmill or bicycle or administration of a pharmaceutical agent that produces the effect of exercise stress in patients unable to ambulate
positron emission tomography (PET) scan of the heart
use of nuclear isotopes & computed tomography techniques to produce perfusion (blood flow) images and study the cellular metabolism of the heart; can be taken @ rest or with stress
radiology
x-ray imaging
angiogram
an x-ray of a blood vessel after injection of contrast medium
coronary angiogram
an x-ray of the blood vessels of the heart
arteriogram
an x-ray of a particular artery (e.g., coronary arteriogram, renal arteriogram)
aortogram
an x-ray of the aorta
venogram
an x-ray of a vein
cardiac catheterization
introduction of a flexible, narrow tube or catheter through a vein or artery into the heart to withdraw samples of blood, measure pressures within the heart chambers or vessels, & inject contrast media for fluoroscopic radiography & cine film (motion picture) imaging of the chambers of the heart & coronary arteries- very often includes interventional procedures such as angioplasty & atherectomy
LT heart catheterization
an x-ray of the LT ventricular cavity & coronary arteries
RT heart catherization
measurement of oxygen saturation & pressure readings of the RT side of the heart
ventriculogram
an x-ray visualizing the ventricles
stroke volume (SV)
measurement of the amount of blood ejected from a ventricle in one contraction
cardiac output (CO)
measurement of the amount of blood ejected from either ventricle of the heart per minute
ejection fraction
measurement of the volume percentage of LT ventricular contents ejected with each contraction
sonography
sonographic imaging
echocardiography (ECHO)
recording of sound waves through the heart to evaluate structure & motion
stress echocardiogram (stress ECHO)
an echocardiogram of the heart recorded during the induction of controlled physical exercise via treadmill or bicycle or administration of a pharmaceutical agent that produces the effect of exercise stress in patients unable to ambulate- useful in detecting conditions such as ischemia and infarction
transesopageal echocardiogram (TEE)
an echocardiogram image of the heart after placement of an ultrasonic transducer @ the end of an endoscope inside the esophagus
Doppler sonography
an ultrasound technique used to evaluate blood flow to determine the presence of a deep vein thrombosis (DVT) or carotid insufficiency, or flow through the heart, chambers, valves, etc.
intravascular sonography
ultrasound images made after a sonographic transducer is placed @ the tip of a catheter within a blood vessel-done to evaluate pathological conditions such as buildup of plaque
coronary artery bypass graft (CABG)
grafting of a portion of a blood vessel retrieved from another part of the body to bypass an occluded coronary artery, restoring circulation to myocardial tissue; the traditional method includes temporary arrest of the heart with circulation (bypass) of the patient's blood through a heart-lung machine during the procedure-an alternative off-pump approach uses a stabilizer to perform the procedure on the beating heart
anastomosis
opening; joining of two blood vessels to allow flow from one to the other
endarterectomy
incision & coring of the lining of an artery to clear a blockage caused by a clot or atherosclerotic plaque buildup (e.g., carotid endarterctomy)
transmyocardial revascularization (TMR)
a laser technique used to open tiny channels in the heart muscle to restore blood flow, thereby relieving angina in patients with advanced coronary artery disease; an option for patients not treatable with angioplasty or coronary artery bypass
valve replacement
surgery to replace a diseased heart valve with an artificial one

types of artificial valves:

TISSUE-most commonly made from animal tissue such as porcine (pig) or bovine (cow)

MECHANICAL- made from synthetic material
valvuloplasty
repair of a heart valve
endovascular surgery
interventional procedures performed endoscopically at the time of cardiac catheterization
angioscopy
use of a flexible fiberoptic angioscope accompanied by an irrigation system, a camera, a video recorder, and a monitor that is guided through a specific blood vessel to visually assess a lesion and select the mode of theraphy
atherectomy
excision of atheromatous plaque from within an artery utilizing a device housed in a flexible catheter that selectively cuts away or pulverizes tissue buildup
percutaneous transluminal coronary angioplasty (PTCA)
a method of treating the narrowing of a coronary artery by inserting a specialized catheter with a balloon attachment, then inflating it to dilate & open the narrowed portion of the vessel & restore blood flow to the myocardium; most often includes placement of a stent
intravascular stent
implantation of a device used to reinforce the wall of a vessel & ensure its patency (openness)- most often used to treat a stenosis or a dissection (a split or tear in the wall of a vessel) or to reinforce patency of a vessel after angioplasty
defibrillation
termination of ventricular fibrillation by delivery of an electrical stimulus to the heart, most commonly by applying electrodes of the defibrillator externally to the chest wall but can be performed internally at the time of open heart surgery or via an implanted device
defibrillator
a device that delivers the electrical stimulus in defibrillation
cardioversion
termination of tachycardia either by pharmaceutical means or by delivery of electrical energy
impantable cardioverter defibrillator (ICD)
an implanted, battery-operated device with rate-sensing leads that monitors cardiac impulses & initiates an electrical stimulus as needed to stop ventricular fibrillation or tachycardia
pacemaker
a device used to treat slow heart rates (bradycardia) by electrically stimulating the heart to contract, most often implanted with lead wires and battery circuitry under the skin but can be temporarily placed externally with lead wires inserted into the heart via a vein
thrombolytic therapy
dissolution of thrombi using drugs streptokinase, tissue plasminogen activator (TPA)
angiotensin-converting enzyme (ACE) inhibitor
a drug that suppressess the conversion of angiotensin in the blood by the angiotension-converting enzyme; used in the treatment of hypertension
antianginal
a drug that dilates coronary arteries, restoring oxygen to the tissues to relieve the pain of angina pectoris
antiarrhythmic
a drug that counteracts cardiac arrhythmia
anticogulant
a drug that prevents clotting of the blood commonly used in treating thrombophlebitis & myocardial infarction
antihypertensive
a drug that lowers blood pressure
beta-adrenergic blocking agents

beta blockers
agents that inhibit responses to sympathetic adrenergic nerve activity causing a slowing of electrical conduction & heart rate & a lowering of the pressure within the walls of the vessels; used to treat angina pectoris & hypertension
calcium channel blockers
agents that inhibit the entry of calcium ions in heart muscle cells causing a slowing of the heart rate, lessening the demand for oxygen & nutrients, and relaxing of the smooth muscle cells of the blood vessels to cause dilation; used to preent or treat angina pectoris, some arrhythmias, and hypertension
cardiotonic
a drug that increases the force of myocardial contractions in the heart commonly used to treat congestive heart failure
diuretic
a drug that increases the secretion of urine commonly prescribed in treating hypertension
hypolipidemic
a drug that reduces serum fat & cholesterol
statins
agents that lower cholesterol in the blood by inhibiting the effect of HMG-CoA reductase, a liver enzyme responsible for producing cholesterol
thrombolytic agents
drugs used to dissolve thrombi (blood clots)
vasoconstrictor
a drug that causes narrowing of the blood vessels, decreasing blood flow
vasodilator
a drug that causes dilation of the blood vessels, increasing blood flow
blast/o

-blast
germ or bud
chrom/o

chromat/o
color
chyl/o
juice
hem/o

hemat/o
blood
immun/o
safe
lymph/o
clear fluid
morph/o
form
myel/o
bone marrow (also spinal cord)
phag/o
eat or swallow
plas/o
formation
reticul/o
a net
splen/o
spleen
thromb/o
clot
thym/o
thymus gland
plasma
liquid portion of the blood & lymph containing water, proteins, salts, nutrients, hormones, vitamins, & cellular components (leukocytes, erythrocytes, & platelets)
serum
liquid portion of the blood left after the clotting process
erythrocyte
red blood cell that transports oxygen & carbon dioxide within the bloodstream
hemoglobin
protein-iron compound contained in the erythrocyte that has bonding capabilities for the transport of oxygen & carbon dioxide
leukocyte
white blood cell that protects the body from invasion of harmful substances
granulocytes
a group of leukocytes containing granules in their cytoplasm
neutrophil
a granular leukocyte, named for the neutral stain of its granules, that fights infection by swallowing bacteria (phagocytosis) (neutro = neither; phil = attraction for)
polymorphonuclear leukocyte (PMN)
another term for neutrophil, named for the many segments present in its nucleus (poly = many; morpho = form; nucleus = kernel)
band
an immature neutrophil
eosinophil
a granular leukocyte, named for the rose-color stain of its granules, that increases with allergy & some infections [eos = dawn-colored (rosy); phil = attraction for]
basophil
a granular leukocyte, named for the dark stain of its granules, that brings anticoagulant substances to inflamed tissues (baso = base; phil = attraction for)
agranulocytes
a group of leukocytes without granules in their nuclei
lymphocyte
an agranulocytic leukocyte that is active in the process of immunity- there are four categories of lymphocytes:
T cells (thymus dependent)
B cells (bone marrow derived)
NK cells (natural killer)
K-type cells
monocyte
an agranulocytic leukocyte that performs phagocytosis to fight infection (mono = one)
platelets
thrombocytes; cell fragments in the blood essential for blood clotting (coagulation)
thymus
the primary gland of the lymphatic system, located within the mediastinum; helps maintain the body's immune response by producing T lymphocytes
spleen
the organ between the stomach & diaphragm that filters out aging blood cells, removes cellular debris by performing phagocytosis, & provides the environment for the initiation of immune responses by lymphocytes
lymph
fluid originating in the organs & tissues of the body that is circulated through the lymph vessels
lymph capillaries
microscopic vessels that draw lymph from the tissues to the lymph vessels
lymph vessels
vessels that receive lymph from the lymph capillaries & circulate it to the lymph nodes
lacteals
specialized lymph vessels in the small intestine that absorb fat into the bloodstream (lacteus = milky)
chyle
a white or pale yellow substance of the lymph that contains fatty substances absorbed by the lacteals
lymph nodes
many small oval structures that filter the lymph received from the lymph vessels-major locations include the cervical region, axillary region, & inguinal region
lymph ducts
collecting channels that carry lymph from the lymph nodes to the veins
RT lymphatic duct
receives lymph from the upper-right part of the body
thoracic duct
receives lymph from the LT side of the head, neck, chest, abdomen, LT arm, & lower extremities
antigen
a substance that, when introduced to the body, causes the formation of antibodies against it
antibody
a substance produced by the body that destroys or inactivates an antigen that has entered the body
immunoglobulins (Ig)
protein antibodies secreted by B lymphocytes that protect the body from invasion of foreign pathogens; the five major classes include IgA, IgD, IgE, IgG, and IgM
immunity
process of disease protection induced by exposure to an antigen
active immunity
an immunity that protects the body against a future infection, as the result of antibodies that develop naturally after contracting an infection or artificially after administration of a vaccine
passive immunity
an immunity resulting from antibodies that are conveyed naturally through the placenta to a fetus or artificially by injection of a serum containing antibodies
microcytosis
the presence of small red blood cells
macrocytosis
the presence of large red blood cells
anisocytosis
the presence of red blood cells of unequal size (an = without; iso = equal)
poikilocytosis
the presence of large, irregularly shaped red blood cells
reticulocytosis
an increase of immature erythrocytes in the blood
erythropenia
an abnormally reduced number of red blood cells
lymphocytopenia
an abnormally reduced number of lymphocytes
neutropenia
a decrease in the number of neutrophils
pancytopenia
an abnormally reduced number of all cellular components in the blood
hemolysis
breakdown of the red blood cell membrane
immunocompromised
impaired immunological defenses caused by an immunodeficiency disorder or therapy with immunosuppressive agents
immunosuppression
impaired ability to provide an immune response
lymphadenopathy
the presence of enlarged (diseased) lymph nodes
splenomegaly
enlargement of the spleen
acquired immunodeficiency syndrome (AIDS)
a syndrome caused by the human immunodeficiency virus (HIV) that renders immune cells ineffective, permitting opportunistic infections, malignancies, & neurological diseases to develop; it is transmitted sexually or through exposure to contaminated blood
anemia
a condition in which there is a reduction in the # of red blood cells, the amount of hemoglobin, or the volume of packed red cells in the blood, resulting in a diminished ability of the red blood cells to transport oxygen to the tissues; common types follow:
aplastic anemia
a normocytic-normochromic type of anemia characterized by the failure of bone marrow to produce red blood cells
iron deficiency anemia
a microcytic-hypochromic type of anemia characterized by a lack of iron, affecting production of hemoglobin & characterized by small red blood cells containing low amounts of hemoglobin
pernicious anemia
a macrocytic-normochromic type of anemia characterized by an inadequate supply of vitamin B12, causing red blood cells to become large, varied in shape, and reduced in #
autoimmune disease
any disorder characterized by abnormal function of the immune system that causes the body to produce antibodies against itself, resulting in tissue destruction or loss of function; rhematoid arthritis and lupus are examples of autoimmune diseases
erythroblastosis fetalis
a disorder that results from the incompatibility of a fetus with an Rh-positive blood factor & a mother who is Rh negative, causing red blood cell destruction in the fetus; necessitates a blood transfusion to save the fetus
Rh factor
the presence, or lack, or antigens on the surface of red blood cells that may cause a reaction between the blood of the mother & fetus, resulting in fetal anemia
Rh positive
the presence of antigens
Rh negative
the absence of antigens
hemochromatosis
a hereditary disorder that results in an excessive buildup of iron deposits in the body
hemophilia
a group of hereditary bleeding disorders in which there is a defect in clotting factors necessary for the coagulation of blood
leukemia
a chronic or acute malignant (cancerous) disease of the blood-forming organs, marked by abnormal leukocytes in the blood & bone marrow; classified according to the types of white cells affected (e.g., myelocytic, lymphocytic)
myelodysplasia
a disorder within the bone marrow characterized by the proliferation of abnormal stem cells (cells that give rise to the different types of blood cells); usually develops into specific type of leukemia
lymphoma
any neoplastic disorder of lymph tissue, usually malignant, as in Hodgkin disease
metastasis
the process by which cancer cells are spread by blood or lymph circulation to distant organs
mononucleosis
a condition caused by the Epstein-Barr virus characterized by an increase in mononuclear cells (monocytes & lymphocytes) in the blood, along with enlarged lymph nodes (lymphadenopathy), fatigue, & sore throat (pharyngitis)
polycythemia
an increase in the # of erythrocytes & hemoglobin in the blood
septicemia
a systemic disease caused by the infection of microogranisms & their toxins in the circulating blood
thrombocytopenia
a bleeding disorder characterized by an abnormal decrease in the # of platelets in the blood, which impairs the clotting process
blood chemistry
a test of the fluid portion of the blood to measure the presence of a chemical constituent (e.g., glucose, cholesterol)
blood chemistry panels
specialized batteries of automated blood chemistry tests performed on a single sample of blood; used as a general screen for disease or to target specific organs or conditions (e.g., metabolic panel, lipid panel, arthritis panel)
basic metabolic panel
battery of tests used as a general screen for disease: calcium, carbon dioxide (CO2), chloride, creatinine, glucose, potassium, sodium and blood urea nitrogen (BUN)
comprehensive metabolic panel
tests in addition to basic metabolic panel for expanded screening purposes: albumin, bilirubin, alkaline phosphatase, protein, ALT, and AST
blood culture
a test to determine if infection is present in the bloodsteam by isolating a specimen of blood in an environment that encourages the growth of microorganisms; the specimen is observed and the organisms that grow in the culture are identified
CD4 cell count
a measure of the number of CD4 cells (a subset of T lymphocytes) in the blood; used in monitoring the course of HIV and timing the treatment of AIDS; the normal adult range is 600-1,500 cells
complete blood count (CBC)
the most common laboratory blood tests performed as a screen of general health or for diagnostic purposes; the following is a listing of the component tests included in a CBC
white blood count (WBC)
a count of the number of white blood cells per cubic millimeter obtained by manual or automated laboratory methods
red blood cell count (RBC)
a count of the # of red vlood cells per cubic mm obtained by manual or automated laboratory methods
hemoglobin (HGB or Hgb)
a test to determine the blood level of hemoglobin (expressed in grams)
hematocrit (HCT or Hct)
a measurement of the percentage of packed red blood cells in a give volume of blood
blood indices
calculations of RBC, HGB, and HCT results to determine the average size, hemoglobin concentration, and content of red blood cells for classification of anemia
mean corpuscular (cell) hemoglobin (MCH)
a calculation of the content in weight of hemoglobin in the average red blood cell using HGB and RBC results
MCH = HGB/RBC
mean corpuscular (cell) hemoglobin concentration (MCHC)
a calculation of the average hemoglobin concentration in each red blood cell using HGB & HCT results: MCHC = HGB/HCT
differential count
a determination of the # of each type of white blood cell (leukocyte) seen on a stained blood smear; each type is counted & reported as a percentage of the total examined
red cell morphology
as part of identifying & counting the WBCs, the condition of the size & shape of the red blood cells in the background of the smeared slide is noted
platelet count (PLT)
a calculation of the # of thrombocytes in the blood: normal range 150,000-450,000/cubic millimeters
erthrocyte sedimentation rate (ESR)
a timed test to measure the rate @ which red blood cells settle or fall through a given volume of plasma
partial thromboplastin time (PTT)
a test to determine coagulation defects such as platelet disorders
thromboplastin
a substance present in tissues, platelets, and leukocytes that is necessary for coagulation
prothrombin time (PT)
a test to measure the activity of prothrombin in the blood
prothrombin
a protein substance in the blood that is essential to the clotting process
venipuncture

phlebotomy
an incision into or puncture of a vein to withdraw blood for testing
bone marrow aspiration
a needle aspiration of bone marrow tissue for pathological examiniation
bone marrow biopsy
a pathological examination of bone marrow tissue
lymphangiogram
an x-ray image of a lymph node or vessel taken after injection of a contrast medium
computed tomography (CT)
full-body x-ray CT images are used to detect tumors & cancers such as lymphoma
positron emission tomography (PET)
radionuclide scans, especially of the whole body, are useful in determining the recurrence of cancers of to measure response to therapy; commonly used in evaluating lymphoma
bone marrow transplant
the transplantation of healthy bone marrow from a compatible donor to a diseased recipient to stimulate blood cell production
lymphadenotomy
an incision into a lymph node
lymphadenectomy
the removal of a lymph node
lymph node dissection
the removal of possible cancer-carrying lymph nodes for pathological examination
splenectomy
the removal of the spleen
thymectomy
the removal of the thymus gland
blood transfusion
the introduction of blood products into the circulation of a recipient whose blood volume is reduced or deficient in some manner
autologous blood
blood donated by, and stored for, a patient for future personal use (e.g, upcoming surgery)
homologous blood
blood voluntarily donated by any person for transfusion to a compatible recipient
blood component therapy
the transfusion of specific blood components such as packed red blood cells, platelets, & plasma
crossmatching
a method of matching a donor's blood to the recipient by mixing a sample in a test tube to determine compatibility
chemotherapy
the treatment of malignancies, infections, and other diseases with chemical agents that destroy selected cells or impair their ability to reproduce
immunotherapy
the use of biological agents to prevent or treat disease by stimulating the body's own defense mechanisms; as seen in the treatment of AIDS, cancer, and allergy
plasmapheresis
the removal of plasma from the body with separation & extraction of specific elements (such as platelets) followed by reinfusion (apheresis = a withdrawal)
anticoagulant
a drug that prevents clotting of the blood
hemostatic
a drug that stops the flow of blood within the vessels
vasocontrictor
a drug that causes a narrowing of blood vessels, decreasing blood flow
vasodilator
a drug that causes dilation of blood vessels, increasing blood flow