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91 Cards in this Set

  • Front
  • Back
the outermost skin layer?
epidermis
Two major types of epidermal cells include?
melanocytes (5%) and keratinocytes (90%).
Melanocytes contain melanin, a pigment giving color to skin and hair and protecting the body from damaging ultraviolet (UV) sunlight. More melanin results in
darker skin color
Keratinocytes produce a fibrous protein called keratin, which is
vital as a protective barrier of the skin.
second skin layer or the connective tissue below the epidermis?
dermis
The dermis is divided into two layers:
upper thin papillary layer and deeper, thicker reticular layer.
Collagen forms the largest part of the dermis and is responsible for the?
mechanical strength of the skin.
The dermis is highly vascular and assists in the regulation of body temperature and blood pressure by supporting the
nerve and vascular networks.
The subcutaneous layer is composed of?
fat and loose connective tissue.
The fat in the subcutaneous layer does what?
insulates the body and provides protection from trauma.
Skin appendages include hair, nails, and?
glands (sebaceous, apocrine, and eccrine).
Hair and nails form from specialized keratin that becomes?
hardened
Pigmented longitudinal bands (melanonychea striata) may occur in the nail bed in most people with?
dark skin
Sebaceous glands secrete sebum, which is emptied into hair follicles. Sebum prevents ?
skin and hair from becoming dry
Apocrine sweat glands are located in the axillae, breast areolae, umbilical and anogenital areas, external auditory canals, and eyelids. They secrete a thick, milky substance that becomes odoriferous when altered by ?
skin surface bacteria
Eccrine sweat glands are widely distributed over the body, except in a few areas such as lips. These glands cool the body by? (and two more functions)
evaporation, excrete waste products through skin pores, and moisturize surface cells.
The primary function of skin is to protect underlying body tissues by serving as a?
surface barrier to the external environment. Skin is also a barrier against bacteria, viruses, and excessive water loss.
The esthetic functions of the skin include the expression of
emotions and displaying individual identity.
With aging, the following changes occur in the skin?
fewer melanocytes (gray and white hair), less volume in the dermis, nail plate thinning, nails become brittle and prone to splitting and yellowing, nails may thicken with age (especially toenails), skin wrinkling, decreased subcutaneous fat, hypothermia, and skin shearing.
A number of benign and premalignant neoplasms related to aging can occur, placing the elder at risk for?
carcinomas
Information related to sensitivities should be obtained. History of chronic or unprotected exposure to
UV light, including tanning bed use and radiation treatments, should be noted.
The skin should be inspected for ?
general color and pigmentation, vascularity, bruising, tattoos and piercings, and presence of lesions or discolorations.
Palpate skin for information about ?
temperature, turgor and mobility, moisture, and texture.
Primary skin lesions develop on previously unaltered skin. These include?
macule, papule, vesicle, plaque, wheal, and pustule.
Secondary skin lesions change with time or occur because of factors such as scratching or infection and include
fissure, scale, scar, ulcer, and excoriation.
Individuals with dark skin are predisposed to
keloids, dermatosis papulosa nigra, Nevus of Ota, traction alopecia, and pseudofolliculitis
dermatoscopy?
using a lighted instrument and magnification
Biopsy is one of the most common diagnostic tests in evaluation of skin lesions. Techniques include?
punch, incisional, excisional, and shave biopsies.
Other diagnostic procedures for skin include
stains and cultures for fungal, bacterial, and viral infections as well as patch testing.
Actinic keratoses, basal cell carcinoma, squamous cell carcinoma, and malignant melanoma are problems associated with?
sun exposure
Skin cancer is the most common malignant condition. Nonmelanoma skin cancers are
neoplasms of the epidermis
Patients should be taught to self-examine their skin monthly. The cornerstone of self-skin examination is the ABCDE rule. Examine skin lesions for
Asymmetry, Border irregularity, Color change/variation, Diameter of 6 mm or more, and Evolving in appearance.
a premalignant form of squamous cell carcinoma (SCC) affecting nearly all the older white population.
?
Actinic keratosis
A typical actinic lesion is ?
an irregularly shaped, flat, slightly erythematous papule with indistinct borders and an overlying hard keratotic scale or horn.
actinic lesion Treatments include?
cryosurgery, fluorouracil (5-FU), surgical removal, tretinoin (Retin-A), chemical peeling agents, laser resurfacing, photodynamic therapy, and dermabrasion.
a locally invasive malignancy from epidermal basal cells.
o Treatment includes surgical excision, electrodesiccation and curettage, cryosurgery, topical and systemic chemotherapy, photodynamic therapy, and radiation therapy.
o The cure rate is greater than 90% with treatment??????
basal cell carcinoma
a malignant neoplasm of keratinizing epidermal cells.
?
Squamous cell carcinoma (SCC)
Squamous cell carcinoma (SCC) Treatment includes ??
surgical excision, electrodesiccation and curettage, excision, radiation therapy, photodynamic therapy, and intralesional injection of 5-FU or methotrexate.
Malignant melanoma tumors arise in?
melanocytes

It is the deadliest skin cancer, and its incidence is increasing faster than that of any other cancer.
Important prognostic factor of melanoma is tumor thickness at the time of diagnosis. Stage 0 is % curable?
Stage 4 % curable?
100 and 0 basically
Melanoma can metastasize to any organ. If it has spread to lymph nodes or nearby sites what is needed?
chemotherapy, biologic therapy, and/or radiation therapy is often required.
People with dysplastic nevus syndrome are at an?
increased risk for melanoma
Staphylococcus aureus and group A β-hemolytic streptococci are?
major types of bacteria responsible for primary and secondary skin infections.
the most common viral infections affecting the skin?
Herpes simplex, herpes zoster, and warts
Allergies and hypersensitivity reactions may present as contact dermatitis and ?
other lesions
A careful history involving exposure to possible offending agents and patch testing are useful in determining the causative agent. The best treatment then becomes?
to avoid the agent
The most common benign dermatologic problems are ?
acne, psoriasis, and seborrheic keratoses.
Psoriasis is a chronic, autoimmune dermatitis characterized by?
silvery, scaling plaques on the elbows, knees, palms, and soles.
Ultraviolet light (UVL) of different wavelengths may be used to treat many dermatologic conditions including?
psoriasis, cutaneous T-cell lymphoma, atopic dermatitis, vitiligo, and pruritis.
Antibiotics are used topically and systemically to treat dermatologic problems. Common over-the-counter topical antibiotics include ?
bacitracin, monocycline, and polymyxin B.
Corticosteroids are particularly effective in treating a wide variety of dermatologic conditions and are used topically, intralesionally, or systemically. High-potency corticosteroids may produce side effects when use is prolonged, including?
skin atrophy, rosacea eruptions, severe exacerbations of acne vulgaris, and dermatophyte infections.
Oral antihistamines are used to treat conditions that exhibit ?
urticaria, angioedema, and pruritus
Diagnostic and surgical therapy techniques include skin ?
scraping, electrodesiccation and electrocoagulation, curettage, punch biopsy, cryosurgery, and excision.
Tissue biopsy is the definitive test for diagnosing a number of ?
skin lesions, particularly cancers of the skin.
commonly used when skin is oozing from infection and/or inflammation, to relieve itching, to suppress inflammation, and to debride a wound.?
wet dressings
Factors affecting the outcome of long-term dermatologic problems include ?
skin type, history of previous exacerbations, family history, complications, intolerance to therapy, environmental factors, and lack of adherence to the prescribed regimen.
Skin grafts may be necessary to provide protection to underlying structures or to reconstruct areas for cosmetic or functional purposes. Ideally, wounds heal by?
primary intention
Two types of grafts are free grafts and skin flaps. Soft tissue expansion is a technique for ?
resurfacing a defect, such as a burn scar; removing a disfiguring mark, such as a tattoo; or as a preliminary step in breast reconstruction.
body tissue injuries caused by heat, cold, chemicals, electrical current, or radiation?
Burns
The resulting effect of burns is influenced by the?
temperature of the burning agent, the duration of contact time, and the tissue type injured.
tissue injury and destruction from acids, alkalis, and organic compounds. ?
Chemical burns
inhalation of hot air or noxious chemicals. There are three types: metabolic asphyxiation, upper airway injuries, and lower airway injuries?
Smoke and inhalation injuries
result of intense heat generated from an electric current. The severity depends on the amount of voltage, tissue resistance, current pathways, surface area in contact with the current, and length of time that the current flow was sustained?
electrical burns
Burn treatment is related to injury severity. Severity is determined by the extent of the burn, as calculated by?
the percent of the total body surface area (TBSA) burned; the depth of the burn (determined by the degree of tissue destruction); location of the burn (e.g., face, hands, perineum); and patient risk factors (e.g., age, past medical history).
Burns are defined by degrees:
first degree (same as sunburn), second degree, third degree, and fourth degree.
A more precise definition of second-, third-, and fourth-degree burns includes the depth of skin destruction:
partial thickness and full thickness.
Partial- and full-thickness burn extent can be determined using TBSA based on two guides:
Lund-Browder chart and Rule of Nines. Burn extent is often revised after edema subsides and demarcation of injury zones occurs.
Face, neck, and circumferential burns to the chest/back area may inhibit?
respiratory function with mechanical obstruction resulting from edema or leathery, devitalized tissue (eschar) formation. These injuries may cause inhalation injury and respiratory mucosal damage.
Circumferential burns to extremities can cause circulatory compromise distal to the burn and may need an
escharotomy or fasciotomy.
Burn management is organized chronologically into three phases:
emergent (resuscitative), acute (wound healing), and rehabilitative (restorative). Overlaps in care exist from one phase to another.
Emergent Phase
• This is the period of time required to resolve immediate, life-threatening problems. It usually lasts
48 to 72 hours
The greatest threat in the emergent phase is?
hypovolemic shock and edema formation.
Toward the end of the phase, if fluid replacement is adequate, the capillary membrane permeability is
restored
Areas of full-thickness and deep partial-thickness burns are initially anesthetic because the nerve endings are destroyed. Superficial to moderate partial-thickness burns are
extremely painful
Most burn patients are alert. Unconsciousness or altered mental status is usually a result of ?
hypoxia associated with smoke inhalation, head trauma, or excessive sedation or pain medication.
If inhalation injury has occurred, the upper airway is vulnerable to ?
edema formation and obstruction of the airway.
If the patient is hypovolemic, kidney blood flow may decrease, causing renal ischemia. If it continues, acute kidney injury may develop. With full-thickness and electrical burns, myoglobin and hemoglobin are released into the bloodstream and can occlude the
renal tubules
The primary goals of wound care are ?
coverage and prevention of infection.
Early and aggressive nutritional support decreases mortality and complications, optimizes healing of the burn, and minimizes negative effects of?
hypermetabolism and catabolism.
Venous thromboembolism prophylaxis should be initiated if not
contraindicated
The acute phase begins with the mobilization of extracellular fluid and subsequent diuresis and concludes when burned area is
completely covered by skin grafts or when wounds are healed. This may take weeks or many months
Partial-thickness wounds form eschar, which begins separating fairly soon after injury. Once the eschar is removed, re-epithelialization appears as
red or pink scar tissue.
Margins of full-thickness eschar take longer to separate. As a result, they require
surgical debridement and skin grafting for healing.
Because the body is trying to reestablish fluid and electrolyte homeostasis, it is important for you to follow the patient’s serum electrolyte levels closely, particularly for changes in ?
sodium and potassium levels.
acute phase Complications include wound infection progressing to
sepsis
Other problems that may develop during the acute phase include:
Paralytic ileus may result if the patient becomes septic.
o Patients can become extremely agitated, withdrawn, or combative during this phase of recovery.
o As scar tissue forms, there may be the development of limited range of motion with contractures.
The predominant therapeutic interventions in the acute phase are?
wound care, excision and grafting, pain management, physical and occupational therapy, nutritional therapy, and psychosocial care.
Current management of full-thickness burn wounds involves early removal of the ?
necrotic tissue followed by application of split-thickness autograft skin. Interventions afterward are aimed at promoting rapid, moist wound healing; decreasing pain at the site; and preventing infection.
Individualized and ongoing pain assessment and intervention are essential. Note two kinds of pain:
(1) continuous, background pain existing throughout the day and night and (2) treatment pain associated with dressing changes, ambulation, and rehabilitation activities.
Burns Range of motion can be performed during wound care to reduce ?
contractures
Rehabilitation begins when wounds have healed and the patient is able to participate in self-care activity. This may occur as early as 2 weeks or as long as
7 -8 months