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34 Cards in this Set

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Complement

One of the most important proteins of this system is the component called
.C3.
To defend the body against foreign molecules or cells, the complement system may

stimulate =
2ct
phagocytosis

induce lysis of microorganisms
.
.
.
Function of the immune system is regulated by a large number of molecules, mainly =
2ct
cytokines, which are
peptides
or
glycoprotein's
with low molecular masses.
influence both the cellular and humoral immune responses.
Cytokines
Cytokines
are primarily produced by cells of the immune system, mainly =
3/2
leukocytes
lymphocytes
macrophages

also be synthesized by
endothelial cells
fibroblasts
______ & ______ are cytokines that induce the attraction of leukocytes to sites of inflammation.
Chemokines
Chemotaxins
a family of species-specific proteins
synthesized by eukaryotic cells in response to viruses
and a variety of natural and synthetic stimuli.
Interferons


List the 3 jobs they perform from the Picture
Interferons


List the 3 jobs they perform from the Picture
Lymphocytes are classified as =
3 ct
B
T
natural killer (NK)
B
T
natural killer (NK)

are what class of cells
Lymphocytes
The B and T cells are the only cells that have the ability to selectively recognize a specific =
epitope
B and T cells
have different surface proteins (markers).

their life history, surface receptors, and behavior during an immune response.
all lymphocyte types originate in the
bone marrow
B cells can recognize
Soluable Antigens
T Cells can not recognize
Soluable Antigens
Every cell has MHC one or two ?
MHC 1
Not all activated B cells become =
plasma cells;

some remain =
B memory lymphocytes,
stopped @ 34
.
Main Fctn CYTOKINE 1

Type =
Growth & Differentiation fctr for Bone Marrow Cells
GM-CSF
M-CSF
Main Fctn CYTOKINE 1

Type =
Inflammation / Fever
TNF-a
IL-1
IL-6
Main Fctn CYTOKINE 1

Type =
Stimulation of Innate Specific response
IL-12
Main Fctn CYTOKINE 1

Type =
GF for T/B Cells
IL-2
IL-3
IL-4
Main Fctn CYTOKINE 1

Type =
Eosinophil Differentiation & activation
IL-5
Main Fctn CYTOKINE 1

Type =
Activation of Macrophages
Interferon-7
Main Fctn CYTOKINE 1

Type =
Regulation of Immune Response
TGF-beta
IL-10
Main Fctn CYTOKINE 1

Type =
Antiviral Activity
Interferon-beta
Interferon-a
Type = CYTOKINE 1
Main Fctn

GM-CSF
M-CSF
Growth & Differentiation fctr for Bone Marrow Cells
Type = CYTOKINE 1
Main Fctn
TNF-a
IL-1
IL-6
Inflammation / Fever
Type = CYTOKINE 1
Main Fctn

IL-12
Stimulation of Innate Specific response
Type = CYTOKINE 1
Main Fctn

IL-2
IL-3
IL-4
GF for T/B Cells
Type = CYTOKINE 1
Main Fctn

IL-5
Eosinophil Differentiation & activation
Type = CYTOKINE 1
Main Fctn

Interferon-7
Activation of Macrophages
Type = CYTOKINE 1
Main Fctn

IL-10
TGF-beta
Regulation of Immune Response
Type = CYTOKINE 1
Main Fctn

Interferon-a
Interferon-beta
Antiviral Activity