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5 Cards in this Set
- Front
- Back
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ONCOGENES
- define - Unmutated counter parts called |
- Genes that promote autonomous cell growth in CA cells
- Proto-oncogenes |
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ONCOGENES
- created by - has the ability to promote cell growth in the absence of what? |
- mutation of proto-oncogenes
- Normal growth promoting signals |
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ONCOGENES
- oncoproteins are devoid of? - oncoproteins do NOT depend on? |
- Internal Regulatory Elements (IRE)
- GFs or other external signals |
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ONCOPROTEINS
- serve many functions along |
- cell's Signal Transduction Pathway
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ONCOGENES & GROWTH FACTORS
"C-SIS" - encodes what? - cancer causing mode of action? - causing what CA? |
- PDGF
- overexpression - Astrocytoma - Osteosarcoma |
