M2-C4-L20 --> Neoplasia I (Benign Classification)

Front 1

Define Neoplasia.

Back 1

Process of new growth

Front 2

Define Neoplasm.

Back 2

New growth

Front 3

Define Oncology

Back 3

Study of tumor

Front 4

Define Cancer

Back 4

Common term for malignancy

Front 5

What are the two components of neoplasms.

Back 5

1. Parenchyma

2. Stroma

Front 6

PARENCHYMA

- what type of cells are they?

- they function to determine what?

Back 6

- Clonal neoplastic cells

- Tumor's Biologic Behavior

Front 7

Reactive Stroma

- is what kind of tissue?

- function?

- amount determines what in tumors?

Back 7

Connective Tissue
(Non-neoplasmic support tissue)

Support tissue for the Parenchyma assisting in angiogenesis and growth.

- consistency of tumors

Front 8

Desmoplasia

- is what?

- occurs due to what stimulation?

Back 8

- Abundant collagenous stroma

- due to stimulation by parenchymal cells

Front 9

BENIGN NEOPLASMS

- List 3 categories of Benign Neoplasms

Back 9

only 1 cell type

> 1 cell type & only 1 germ layer

> 1 cell type & > 1 germ layer

Front 10

BENIGN NEOPLASMS

- 1 cell type category of neoplasms have what 2 subcategories?

Back 10

- Epithelial origin

- Mesenchymal origin

Front 11

BENIGN NEOPLASMS

- In category involving > 1 cell type & 1 germ layer, what is the prototype of this tumor?

Back 11

- Pleomorphic Adenoma

Front 12

BENIGN NEOPLASMS

- In the category involving benign neoplasms of > 1 cell type & > 1 germ layer, give an example?

Back 12

- Teratoma

Front 13

List the Benign Epithelial Neoplasm types. x5

Back 13

- Adenoma
- Papilloma
- Cystadenoma

- Papillary Cystadenoma
- Polyps

Front 14

ADENOMA

- Benign or malignant

- arises from what?
OR
- forms what structure?

- list some adenoma examples x5

Back 14

- Benign epithelial neoplasm

- Glands
or
Forms Glandular Structures

- Bronchial adenoma
- Adrenal adenoma
- Renal Tubular adenoma
- Thyroid adenoma
- Hepatic cell adenoma

Front 15

PAPILLOMA

- Benign or malignant

- arises from?

- forms what?

- give 3 examples

Back 15

- Benign epithelial neoplasm

- Surface epithelial

- Delicate Epithelial projections
over
core of Fibro-vascular tissue

- Squamous papilloma of skin, tongue
- Intraductal papilloma of breast
- TC papilloma of bladder and choroid plexus

Front 16

CYSTADENOMA

- Benign or malignant

- arises from?

- forms what?

- common site?

Back 16

- Benign epithelial neoplasm

- gland

- cystic structure

- ovary

Front 17

PAPILLARY CYSTADENOMA

- Benign or malignant?

- arises from?

- forms what? x2

- common site?

Back 17

- Benign Epithelial Neoplasm

- glands

- Cystic structure
- Papillary projections internally

- Ovary

Front 18

POLYPS

- Benign or malignant?

- produces what?

- arises commonly from where? x2

Back 18

- Both

- Visible protrusion above mucosal structure

- Colonic (tubular adenoma)
- Uterine

Front 19

POLYPS

- Malignant Polyps are termed what?

Back 19

- Polypoid Cancers

Front 20

BENIGN MESENCHYMAL TUMORS

- involves what 3 tissue types?

Back 20

- CT

- Endothelial & related tissue

- Muscles

Front 21

BENIGN MESENCHYMAL TUMORS

Benign mesenchymal tumors involving connective tissue
- give 4 examples?

Back 21

- Fibroma

- Lipoma

- Osteoma

- Chondroma

Front 22

BENIGN MESENCHYMAL TUMORS

Benign mesenchymal tumors involving Endothelial & related tissue
- give 3 examples?

Back 22

(MHL)

- Meningioma

- Hemangioma

- Lymphangioma

Front 23

BENIGN MESENCHYMAL TUMORS

Benign mesenchymal tumors involving muscle tissue
- give 2 examples?

Back 23

- Leiomyoma (smooth)

- Rhabdomyoma (striated)

Front 24

ADENOMA

- Benign or malignant

- arises from what?
OR
- forms what structure?

- list some adenoma examples x5

Back 24

- Benign epithelial neoplasm

- Glands
or
Forms Glandular Structures

- Bronchial adenoma
- Adrenal adenoma
- Renal Tubular adenoma
- Thyroid adenoma
- Hepatic cell adenoma

Front 25

PAPILLOMA

- Benign or malignant

- arises from?

- forms what?

- give 3 examples

Back 25

- Benign epithelial neoplasm

- Surface epithelial

- Delicate Epithelial projections
over
core of Fibro-vascular tissue

- Squamous papilloma of skin, tongue
- Intraductal papilloma of breast
- TC papilloma of bladder and choroid plexus

Front 26

CYSTADENOMA

- Benign or malignant

- arises from?

- forms what?

- common site?

Back 26

- Benign epithelial neoplasm

- gland

- cystic structure

- ovary

Front 27

PAPILLARY CYSTADENOMA

- Benign or malignant?

- arises from?

- forms what? x2

- common site?

Back 27

- Benign Epithelial Neoplasm

- glands

- Cystic structure
- Papillary projections internally

- Ovary

Front 28

POLYPS

- Benign or malignant?

- produces what?

- arises commonly from where? x2

Back 28

- Both

- Visible protrusion above mucosal structure

- Colonic (tubular adenoma)
- Uterine

Front 29

POLYPS

- Malignant Polyps are termed what?

Back 29

- Polypoid Cancers

Front 30

BENIGN MESENCHYMAL TUMORS

- involves what 3 tissue types?

Back 30

- CT

- Endothelial & related tissue

- Muscles

Front 31

BENIGN MESENCHYMAL TUMORS

Benign mesenchymal tumors involving connective tissue
- give 4 examples?

Back 31

- Fibroma

- Lipoma

- Osteoma

- Chondroma

Front 32

BENIGN MESENCHYMAL TUMORS

Benign mesenchymal tumors involving Endothelial & related tissue
- give 3 examples?

Back 32

(MHL)

- Meningioma

- Hemangioma

- Lymphangioma

Front 33

BENIGN MESENCHYMAL TUMORS

Benign mesenchymal tumors involving muscle tissue
- give 2 examples?

Back 33

- Leiomyoma (smooth)

- Rhabdomyoma (striated)

Front 34

LIPOMA

- Benign or malignant?

- Describe gross observation. x2

- Most common benign tumor in what population group?

Back 34

- Benign Mesenchymal Tumor of Adipose tissue

- Well circumscribed mass of Mature Adipose Tissue
- Cut surface is yellow

- Males

Front 35

FIBROMA

- benign or malignant?

- Commonly seen where?

Back 35

- Benign Mesenchymal Tumor of Fibrous tissues

- ovary

Front 36

OSTEOMA

- benign or malignant?

- of what tissue?

- Histo-observation

Back 36

- Benign Mesenchymal Tumor

- Bone

- Haphazard Interconnected Tuberculae
(of Woven Bone)

Front 37

CHONDROMA

- Benign or Malignant?

- of what tissue?

Back 37

- Benign mesenchymal Tumor

- Hyaline cartilage

Front 38

CHONDROMA

- gross observation?

- histo observation? x3

Back 38

- Nodular configuration

- Well circumscribed nodule of hyaline cartilage
- Hyaline matrix
- Neoplastic chondrocytes in lacunae

Front 39

HEMANGIOMA

- malignant or benign

- of what tissue?

- Histo observation

Back 39

- Benign tumor

- Blood vessels

- Closely Packed Blood Vessels

Front 40

HEMANGIOMA

- Most common tumor of what population group?

- Most common location of this group is where? x2

- above manifestation called?

Back 40

- Infancy

- Face in infants
- Scalp in infants

- Port-wine stains

Front 41

HEMANGIOMA

- vessels affected?

Back 41

- Capillary (small BV)

- Cavernous (large BV)

Front 42

LYMPHANGIOMA

- benign or malignant

- of what tissue

- characterized by what Histo observation? x2

Back 42

- Benign tumor

- Lymph vessels

- Cystic spaces
- Cavernous spaces

Front 43

LYMPHANGIOMA

- seen in lymph vessels where? x4

Back 43

(RAMS)

- Retro-peritoneum

- Axilla

- Mediastinum

- Skin (or deeper regions of neck)

Front 44

LEIOMYOMA

- benign or malignant

- of what tissue

- common location

- additional location

Back 44

- Benign tumor

- Smooth muscle

- Uterus

- GI Tract

Front 45

LEIOMYOMA

- Diagnostic stain?

- Most common tumor in what population group?

Back 45

- Smooth Muscle Actin

- Females

Front 46

RHABDOMYOMA

- benign or malignant?

- of what tissue

- most common site?

Back 46

- Benign Mesenchymal Tumor

- Striated muscles

- Heart

Front 47

HYDATIDIFORM MOLE

- benign or malignant

- of what tissue

- located usually where?

- Gross observation?

Back 47

- Benign

- Chorionic villi

- Uterus cavity

- Bunch of grapes

Front 48

MELANOCYTIC NEVUS

- Benign or malignant

- of what tissue?

Back 48

- Benign tumor

- Melanocytes

Front 49

Give an example prototype of a Benign neoplasm of > 1 cell type but of only 1 tissue type.

Back 49

- Pleomorphic Adenoma

Front 50

PLEOMORPHIC ADENOMA

- aka

- benign or malignant

- of what tissue?

Back 50

- Mixed tumor

- Benign

- Salivary gland (Parotid)

Front 51

PLEOMORPHIC ADENOMA

- describe the neoplastic cells

- what is the germ origin for these cell types?

Back 51

- 2 different morphological patterns

- both derived from same germ cell layer

Front 52

TERATOMA

- Arises from what cells?

- common in what tissues? x2

Back 52

- Totipotent cells

- Gonads
- Midline Tissues

Front 53

TERATOMA

- Benign form is a ?

- This implies what?

Back 53

- Mature teratoma

- all cells under microscope is in mature form

Front 54

TERATOMA

- what cyst is associated?

- this implies what?

Back 54

- Dermoid cyst

- consists mainly of ectodermal differentiation

Front 55

TERATOMA

- Malignant form is a? x2

Back 55

- Immature teratoma

- Teratocarcinoma

Front 56

What is the most common teratoma in childhood?

Back 56

Sacrococcygeal Teratoma

Front 57

SACROCOCCYGEAL TERATOMA

- most common teratoma during what age phase?

- most common in what population group?

- incidence?

Back 57

- childhood

- Girls associated with Defects in hindgut and cloacal region

- 1:20,000 to 1:40,000

Front 58

MOST COMMON BENIGN CANCER

- in males?

- in females?

- in infancy?

- in childhood?

Back 58

- Lipoma

- Leiomyoma

- Hemangioma

- Sacrococcygeal Teratoma is most common teratoma in childhood