Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
11 Cards in this Set
- Front
- Back
|
painful LAD signifies
painless LAD can be |
an acute infection
chronic infec/inflam, metastatic tumor, lymphoma |
|
|
what types of causes would make follicular hyperplasia |
(b cell)
HIV RA toxoplasmosis |
|
|
what types of causes would make paracortical hyperplasia |
(T cells)
virus, certain drug rxn |
|
|
what types of causes would make sinus changes? |
nonspecific metastatic carcinoma |
|
|
mixed changes in lymph node caused by |
viral cat scratch metastatic carcinoma
|
|
|
what causes granuloma to form in node |
TB fungi sarcoid
|
|
|
malignant lymphoma what is it by definition where is it what genes are common |
clonal proliferation of lymphocytes doesn't have to be in node
BCL6 (maturation), proliferation MYC, survival BCL2 |
|
|
how does pt with malignant lymphoma present |
LAD extra nodal issues: GI, lung liver, BM. Organ dysfunction "B" symptoms = fevers, night sweats, weight loss immune dysfunction Rx toxicity |
|
|
what causes malig lymphoma? |
environmental rad or chemistry infections (H. pylori, EBV) immune defect/chronic immune stimulation hereditary
|
|
|
what's the cell associated with hodgkin's disease |
Reed-Sternberg cell |
|
|
how do hodgkins compare to nonhodgkins in age sex mdiastinal BM Immune defects |
younger 20-40 M>F in both common mediastinal BM uncommon; non depends on type often have cell immunity problems; non is occasional defects |
