Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
20 Cards in this Set
- Front
- Back
- 3rd side (hint)
|
Lung disease associated with industries such as mining and milling of stones and ores, pottery,
sandblasting, |
Silicosis:
|
inhalation of silica, in
|
|
|
How long must you be exposed to Silica b4 presenting?
|
20-40 yrs
|
|
|
|
small nodules on CXR scattered throughout lungs; 5-10% have “eggshell
hilar LN calcifications; usu asymptomatic. Starts in upper lobes on CXR. |
Simple Silicosis
|
A type of Silicosis
|
|
|
conglomerates of silicotic nodules >1cm in diameter; respiratory
complaints common |
Complicated silicosis:
|
|
|
|
Caplan’s syndrome:
|
formation of large necrotic rheumatoid nodules in lungs of pts. with
silicosis who develop RA (rheumatoid arthritis); silicotic nodules undergo necrosis |
|
|
|
T/F, Individuals with Silicosis have a higher risk of developing TB
|
TRUE. Silicotuberculosis: # risk of TB in pts with pneumoconiosis, esp. silicosis
|
|
|
|
A sandblaster takes NO respiratory precaution one day while working. What lung disease does he present with?
|
Acute Silicosis
|
|
|
|
insulation workers, fireproofers, workers in brake linings, are all at risk for this lung disease
|
Asbestosis, (must have 10-20 yrs of exposure)
|
|
|
|
5 clinical manifestations of Asbestosis
|
-Abestosis
-Recurrent pleural effusions -Pleural fibrosis and hyaline plaques (benign) -Bronchogenic carcinoma -Malignant mesothelioma |
|
|
|
What do Asbestos bodies look like?
|
dumbells, (they take up Iron)
|
|
|
|
Exposure to coal dust; if the coal dust has significant
amounts of silica, silicosis may be superimposed on this condition |
Coal Workers Pneumoconiosis
|
|
|
|
Name the 3 Clinical Forms of CWP (Coal Workers Pneumoconiosis)
|
-simple CWP - asymp. exp for black sputum
-Progressive Massive Fibrosis (Complicated CWP) -Typical Nodular lesions of silicosis (May or may not be superimposed with above CWP effects) |
|
|
|
You meet a fluorescent light bulb maker with respiratory problems. He also has some nuclear
and aerospace industry buddies that have similar lung problems. What does he have? |
Berylliosis
Acute - hypersensitivity rxn. to beryllium; Chronic berylliosis: identical to sarcoid under LM; |
|
|
|
4 Radiographic Stages of Sarcoidosis
|
Bilateral hilar lymphadenopathy without infiltrates; lymph nodes are so big they’re sometimes
likened to potatoes; PFTs are often normal at this point, but as the disease progresses into the other stages there will be the characteristic changes of restrictive lung disease 2. Bilat. hilar lymphadenopathy with interstitial infiltrates 3. Interstitial infiltrates only (less enlarged hilar LN because of scarring) 4. Honeycomb lung Clinical course: variable |
|
|
|
Sarcoidosis can have effects throughout the body. Name them:
Heart, GI, GU, eytes, Skin, PNS, CNS, endocrine, Skeletal |
heart: heart block, arrhythmia, failure; or cor pulmonale due to lung fibrosis
GI: hepatic granulomas, # alk phos GU: # serum Ca++ ! hypercalciuria ! kidney stones eyes: uveitis and retinopathy, blurry vision, eye pain, blindness skin: erythema nodosum, erythema multiforme – signs of early disease and good prognosis plaque-like nodules and facial nodules are signs of chronic, progressive disease and carry a poor prognosis PNS: peripheral neuropathy, facial nerve palsy CNS: cerebrum, cerebellum, brainstem, spinal cord lesions – can see these w/ minimal/no evidence of thoracic dz. endocrine: hypercalcemia due to activation of vit D by macrophages, hypopituitarism, diabetes insipidus skeletal: arthritis, arthralgia, bone cysts |
|
|
|
A patient has Erythema Nodosum and Erythema Multiforme. What dz? Any idea about prognosis?
|
Sarcoidosis
Yes! |
|
|
|
Noncaseating granulomas in a young African-American woman. Stains and cultures are negative
|
SARCOIDOSIS
|
|
|
|
Why is it important to rule out infectious causes when diagnosing Sarcoidosis
|
Because txt is immunosuppressive and could exacerbate an undetected infection.
|
|
|
|
Name 7 causes of Intersitial Lung Disease
|
- Autoimmune diseases: RA, MCTD, Scleroderma
- Drug toxicities: ChemoTx: Bleomycin, Amiodarone - Environmental toxins: Asbestos, Silica - Sarcoidosis - Hypersensitiviy Pneumonitis - Eosinophilic Granuloma (HX) - Idiopathic Pulmonary Fibrosis (IPF) |
|
|
|
Name Symptoms of CISLD
|
cough
dyspnea weight loss tachypnea dry rales clubbing – chronic hypoxia PFTs – decreased volume (RESTRICTIVE pattern), decreased No consolidation on CXR; tympanic on auscultation |
|
