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47 Cards in this Set

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What is osteoarthritis?

protective articular caritlage on the ends of bones wears down over time (progressive)


irreversible

Which joints does osteoarthritis affect and which are MC?

weight bearing joints


MC = knee and hip



med. and lat. femoro-tibial, and patellofemoral compartments- tricompartment syndrome of the knee

Which joints does osteoarthritis not affect?

wrist, MCP, ankle, and elbow

What is osteoarthritis associated with?

-genetic predisposition


-W>M


-age, obesity, trauma, metabolic (acromegaly, gout, hyperparathyroid), hyperparathyroidism, hemochromatosis, charcot joint


-congenital defects: subcaptial femoral epiphysis (SCFE), congenital hip dysplasia


-acquired: epiphysis dysplasia

S/S of osteoarthritis

-Herberdens nodes at DIP


-Bouchards nodes at PIP


-fusiform swelling of joints


-loss of ROM


-effusions


-crepitus


-pain


-start up pain- gets better as the day goes on (lasts about 30m)


-Genu algum; severe lat. wear of knee jt causing laxity of med. ligament causing knock knee


-Genu varum; sever med. wear of knee jt causing laxity of lat. ligament (bow legged)

Dx of osteoarthritis

lab studies-


-fluid analysis: synovial fluid debris, absent of crystals, absent of white cells/organism


-serum lab



radiographic findings-


-narrowing of joint space


-osteophytes, chondral irregularity, boney cystic changes, articular surface sclerosis


-osteophytes are secondary bone growth, its the born trying to fix itself

Tx for osteoarthritis

-bracing


-medical management


-pt education (wt. loss, activity precaution)


-exercise (brace PRN)


-cold therapy first then heat


-NSAID (decrease prostaglandins)


-COX-2 Celecoxib (Celebrex), Meloxicam (Mobic): inhibits Cox-1 &2 enzyme and decreasing the conversation of arachidonic acid to PGs; Celebrex is only one that is Cox-2 specific


-cortisone injections: 6-8wks (can repeat)


-hyaluronic acid injections: Hyalgan, Supartz, OrthoVisc, Synvisc, Eufflexa are all only approved for knee injections


-Arthroplasty


-surgical management: conservative fails then total joint arthroplasty on knee, hip, shoulder, elbow, or ankle

What is rheumatoid arthritis?

systemic autoimmune disorder causing inflm synovitis that erodes and destroys articular cartilage

What are extra-articular manifestations of rheumatoid arthritis?

-Heart: pericarditis, vasculitis, valvular, and valve ring nodules, myocarditis


-Lung: pleural effusion, bronchiolitis


-Skin: fragility, nodules, "onion skin" from prednisone


-Neuro: neuropathy, cervical myelopathy, peripheral neuropathy


-Hematology: anemia, thrombocytosis


-Bone: osteopenia


-Eye: sicca, episcleritis, scleromalacia, perforans (sicca = sjorgens: AI disease that destroys exocrine glands that produce tears and saliva)


-Kidney: amyloidosis, vasculitis

What is the etiology behind rheumatoid arthritis?

genetic predisposition + trigger


F>M


35-50 y/o


RA in men <40 is unusual


HLA-DR4 = increased incidence and severity


What joints does rheumatoid arthritis MC affect?

hands, wrist, shoulder, elbows


S/S of rheumatoid arthritis

-bilat symmetric polyarthritis


-malaise and fatigue


-stiffness (esp in morning- lasts 30m)


-pain and tenderness


-effusion


-symmetric arthritis


-rheumatoid nodules


-deformity of hand and finger (ulnar dev., swan neck, boutonniere)

Dx of rheumatoid arthritis

-sx present for >6wks


-4/7 criteria


-acute phase: ESR, CRP, plts


-CBC: anemia (normochromic, normochytic)

Dx Criteria for RA

-morning stiffness


-arthritis >3 jts for >6wks


-arthritis of hand its >6wks


-symmetric arthritis for >6wks


-rheumatoid nodules


- +serum rheumatic factor


-radiographic changes

Osteoarthritis VS RA


-onset


-inflm


-location


-findings


-bone changes


-labs


-tx goal

OA


-gradual


- -


-DIP/WB jts


-herberden's nodes


-osteophytes


-nl


-pain control



RA


-gradual


- +


-MCP/PIP jts


-ulnar deviation, swan neck


-periarticular osteoporosis and erosions


- + Rf, ESR, anemia


-control inflm

What is septic arthritis caused by?

-destruction of synovium and cartilage


-hematogenously or direct inoculation

Who usually gets septic arthritis?

-children after URI


-adults with RA


-adults with gonococci infx


-adults <30 neisseria ghonorrhea

What is the MC bacteria that causes septic arthritis?

staph aureus

S/S of septic arthritis in an infant or child

-acutely ill


-high fever


-tachycardia


-irritability and pain with motion of jt


-child who previously has been walking and now refuses

S/S of septic arthritis in adults

-sepsis is secondary to total jt arthroplasty


-vague discomfort


-limited jt motion


-swelling, deformity


-redness


-warm


-holds it in position of comfort (flex)

how do dx septic arthritis

-DDx: slipped capital femoral epiphysis


-CBC


-ESR


-CRP


-AP/LAT X-rays


-blood cultures


-jt aspiration for fluid analysis


-gram stain and culture

tx for septic arthritis

-abx broad spectrum until culture are back (Amoxicillin, Ciprofloxacin)


-surgical decompression and drainage by arthroscopy or open arthrotomy (esp in hip infix to prevent osteonecrosis)

What is gout?

deposition of crystals in synovium and other tissues causing an inflm process (monosodium irate crystals)

What are joints that gout affects and which is the most common?

MC = great toe


ankle, knee, wrist, elbow

What foods have an elevated uric acid level?

meats, seafood, cheeses, red wine, and beer

What is pseudo gout and who and where do pts get it?

-deposit of Ca Pyrophosphate crystals within the joint


-older ppl


-MC = knee


-acute and painful

Risk factors for gout?

-older


-jt trauma


-gentic disorder (younger pts)


-mineral imbalance (excessive Ca or Fe, too little Mg)


-underactive thyroid or overactive parathyroid

S/S of gout

-severe pain


-last for d-wks


-hot red joint


-acute onset


-awakens from sleep

Dx of gout

-thyroid level


-PTH level


-mineral levels


-uric acid


-needle aspiration to check for crystals (negatively birefringent crystals)


-radiographic: jt damage along with crystal deposits in cartilage

tx for gout

-acute attack: Colchincine, Colcrys, Indomethacin, Indocin, NSAIDS, alopuranol (for chronic)


-Colchincine 0.6mg PO q2h til 1 of 3 occurs: pain goes away, diarrhea, or vomiting


-Indomethacin 50-200mg PO BID or TID


-jt drainage


-ice pack (reduce inflm)


-home remedy = eat dark cherry

What are some causes of ant. hip pain for different age groups?

Adolescents: apophyseal avulsion or SCFE (10-12 y/o AA or hispanic male)


Young Adults: muscle or tendon sprain


Middle Aged and Older Adults: OA, RA, fx


Femoral neck stress fx: constant groin pain; can lead to worse fx if not tx

Dx for hip pain

bone scan with radioactive dye to show femoral stress fx


MRI to confirm


CT to r/o femoral neck fx

tx for hip pain

percutaneous pinning of non-displaced femoral neck fx

What is a hemiarthroplasty?

partial hip replacement for femoral neck fx

What are the two types of hemiarthroplasties?

Uni-polar: ball moves as 1 peeve in 1 plane


Bi-polar: ball moves as 2 pieces in 2 planes

What is an intertrochanteric fx?

when fx goes from greater to lesser trochanter

What is the MC type of hip fracture in elderly pts who fall?

intertrochanteric fx

S/S of intertrochanteric fx

pain


legs will be ext. rotated and short

dx of intertrochanteric fx

xray

tx for intertrochanteric fx

ORIF


screws and compression plate

How do femur fx happen?

falls or high velocity trauma

S/S of femur fx

severe pain


difficulty with weight bearing


affected is shortened (if comminuted) and ex rotated


dehydration (mild)- fallen and can't get up

dx of a femur fx

xray

tx for femur fx

plate


intermedullary nailing


retrograde nail for distal femur fx

What is slipped capital femoral epiphysis?

head of femur slips out of acetabulum

Who gets SCFE and which leg is most common?

adolescent males 10-17 y/o and females 8-15 y/o


Left hip = MC


bilat 25% of the time


when is SCFE considered acute or chronic?

-acute: sx <3wks and sudden onset of sever hip pain inability to wt bear on affected leg


-chronic: gradual onset pain >3wk, pain intermittent in hip or knee


-acute-on-chronic: sudden increase in pain and inability to wt bear after minor tx