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62 Cards in this Set

  • Front
  • Back

Longitudinal Research


• In longitudinal research


– same people are observed repeatedly over time,


and changes in development are recorded


• Typical time of study spans months or a few


years


• Longitudinal researchers must enlist future


researchers to continue the study

Cross-Sectional Research


• Cross-sectional research observes and


compares subjects of different ages


– a larger number of participants is needed for this


type of study

Cohort effect


– Group of people born at the same time will


experience cultural and other events unique to


age group

Cross-Sequential Research


• Combines longitudinal and cross-sectional


methods to overcome research drawbacks


• Breaks up the full span of the ideal


longitudinal study into convenient segments


• Minimizes the number of years needed to


complete a study


• Uses time-lag comparisons

Ethical Considerations


• Do not use methods that may cause physical or


psychological harm


• Inform participants of the purposes of the research and


its methods


• Participation must involve voluntary consent


• Participants may withdraw from study at any time, for


any reason


• Participants are offered information about the results of


the study


• Identities of participants remains confidential


• Research plans are to be presented to a committee of


colleagues and gain approval before proceeding

Genetics

- the field of biology that studies heredity


– Fundamental in the transmission of


physical traits


– Also plays a role in psychological traits

Chromosomes

– Rod-shaped structures composed


of genes that are found within the nuclei of cells


.

Gene

– The basic unit of heredity. Composed of


DNA

Polygenic

– Resulting from many genes

Deoxyribonucleic Acid (DNA)

– Genetic material that


takes the form of a double helix composed of


phosphates, sugars and bases

Mitosis


– Genetic code carried into new cells in our bodies


DNA breaks apart; double helix duplicates


• DNA forms two camps on either side of the cell, and


then the cell divides

Meiosis


• Sperm and ova are produced through meiosis or


reduction division.


• 46 chromosomes within the cell nucleus first line up into


23 pairs.


• DNA ladders unzip, leaving unpaired halves of


chromosome; when cell divides, one member of each


pair goes to each newly formed cell.


• Each new cell nucleus contains only 23 chromosomes,


not 46.

Monozygotic (MZ)


- Zygote divides into two cells that separate so that each


develops into an individual with the same genetic makeup

Dizygotic (DZ)


- Two ova are produced in the same month, each


fertilized by a different sperm cell.

Traits determined by pairs of


genes


– each member of pairs of


genes termed an
__________________

allele

Dominant trait


– trait that is expressed

Recessive trait


– trait that is not expressed


when genes have been paired


with dominant genes

Homozygous


– having two identical alleles

Heterozygous

Heterozygous


– having two different alleles

Incomplete


dominance/codominances


– when both alleles are shown

Carriers


– people who bear one


dominant gene and one


recessive trait

Down syndrome


– Caused by an extra chromosome of the


21st pair, resulting in 47 chromosomes


• Characteristic features


-rounded face


-protruding tongue


-broad, flat nose


-sloping fold of skin over the inner corners of the eyes


• Show deficits in cognitive development


and motor developmen

1 male in 700-1,000 has XYY


– leads to heightened male


secondary sex characteristics


– most individuals with disorder are


infertile

1 male in 500 has Klinefelter


syndrome (XXY)


– leads to inadequate development


of male primary and secondary


sex characteristics

1 female in 2,500 has a single X


resulting in Turner Syndrome


– poorly developed ovaries, short,


and infertile.

female in 1,000 has XXX sex


chromosomal structure called


Triple X syndrome


– normal in appearance but tend to


show lower-than-average language


skills and poorer memory for recent


events

Phenylketonuria (PKU)


• Enzyme disorder transmitted by a recessive gene


affecting 1 child in 8,000


• Cannot metabolize an amino acid called phenylalanine;


builds up in body and impairs functioning of the central


nervous system (CNS)


• Results are mental retardation, psychological disorders,


physical problems


• No cure, but children can be placed on diets low in


phenylalanine and develop normally

Sex-Linked Genetic Abnormalities


• Genetic defects only carried on the X sex chromosome


• Hemophilia – genetic disorder in which blood does not


clot properly


• Duchenne – muscular dystrophy; sex linked


• Involve recessive genes


• Females with two X sex chromosomes are less likely


than males to show sex-linked disorder


• Sons of female carriers are more likely to be afflicted

factors that contribute to development of traits

Inheritance, nutrition, learning, exercise, accident, and


illness

Phenotypes


-Actual set of traits


-Both genetic and environmental influences

Amniocentesis


• Performed on mother 14-16 weeks after conception


• Syringe withdraws fluid from the amniotic sac; contains


cells sloughed off by fetus


• Cells separated, grown in culture, and examined for


genetic and chromosomal abnormalities


• Routine for women over 35 to detect for Down


syndrome; other chromosomal abnormalities increase


dramatically as women approach 40


• Amniocentesis carries some risk of miscarriage.

Chorionic Villus Sampling


• Carried out between 9th and 12th week of pregnancy


• Syringe inserted through vagina into uterus to suck out


threadlike projections (villi) from the outer membrane


that covers the amniotic sac and fetus


• Results available in days


• CVS slightly greater risk than amniocentesis of


miscarriage; both increase the risk of miscarriage

Ultrasound

U


• Sound waves that are too high in frequency to be heard


by human ear obtain information about the fetus


• Ultrasound waves are reflected by the fetus; computer


uses the information to generate a picture of the fetus


• Picture is termed a sonogram


• Used to guide the syringe in amniocentesis and CVS by


determining the position of the fetus


• Used to track growth of fetus, detect multiple


pregnancies, detect structural abnormalities

Blood Tests


• Used to identify sickle-cell anemia, Tay-Sachs disease,


and cystic fibrosis


• Alpha-fetoprotein (AFP) used to detect neural tube


defects such as spina bifida and chromosomal


abnormalities


• Neural tube defects cause elevation in the AFP level in


the mothers blood


• Elevated AFP levels related to increased risk of fetal


death

Prenatal Development


• Normal gestation period

280 days; from date of


fertilization 266 days


Prenatal Development


Divided into three periods


1. Germinal stage (Weeks 0 - 2)


2. Embryonic stage (Weeks 3 - 8)


3. Fetal stage (Weeks 9 - Birth)

The Germinal Stage


• The period from conception to implantation


• Conception refers to the union of an ovum and a sperm


cell to form a zygote


• Within 36 hours after conception, the zygote begins


rapid division process

Implantation happens when ...

fertilized egg attaches


itself to the uterine wall


-At this point, cells begin to specialize and separate into groups that will become different structures


-These cells eventually become the fetus

embryonic disk

Inner part of blastocyst has two distinct layers that form a


thickened mass of cells called embryonic disk

The Embryonic Stage


• Development follows cephalocaudal (head to tail) and proximodistal


(near to far).


• Growth of the head takes precedence over growth of the lower


parts of the body.


• Relatively early maturation of the brain and organs that lie near the


spine


• Cells begin to differentiate/become specialized:

Ectoderm


-Outer layer of cells


-Develops into nervous system, sensory organs, nails, hair,


teeth, and outer layer of skin

Endoderm


-Forms digestive and respiratory system, liver, and pancreas

Mesoderm


-Develops into excretory, reproductive, and circulatory


systems, muscles, the skeleton, and the inner layer of skin

The Fetal Stage


• Lasts from beginning of third month until birth


• Between 9th and 10th, week fetus responds to external


stimulation


• Major organ systems formed at end of first trimester


• Second trimester consists of further maturation and gain


in size


• Weight advances from 1 ounce to 2 pounds and grows


from about 3 to 14 inches

Maternal malnutrition effects


-low birth weight


-prematurity


-retardation of brain development


-cognitive deficiencies


-behavioral problems


-cardiovascular disease


Fetal malnutrition can sometimes be overcome by a supportive,


care-giving environment.


• Supplementing diets of pregnant women shows positive effects on


motor development of infants.


• Maternal obesity linked with higher risk of stillbirth

Teratogens


-Environmental agents can harm the embryo or fetus


-Includes drugs taken by mother, lead, mercury

Pathogens


-Disease-causing organisms


-Bacteria and viruses

Critical periods refer to ....

the times when organs are


developing.


• Particular teratogens at a particular time can be


harmful to the fetus.

Rubella


-Women affected by rubella (German measles) during first 20 weeks of


pregnancy stand 20% chance of bearing children with birth defects such


as deafness, mental retardation, heart disease, eye problems (including


blindness)

Preeclampsia (or Toxemia)


-Life-threatening; characterized by high blood pressure that may afflict


women late in 2nd trimester or early in 3rd trimester

Rh incompatibility


-Consists of antibodies produced by the mother and transmitted to a fetus


or newborn infant that cause brain damage or death

Thalidomide


-A sedative used for treatment of insomnia and nausea


-Causes missing or stunted limbs during second month


of pregnancy

High doses of vitamins A and D


-Associated with central nervous system damage,


small head size, and heart defects

Narcotics (heroine, methadone)

easily pass placental


membrane and cause fetuses to become addicted.


-After birth, drug is substituted so serious


withdrawal symptoms are minimized


-Addicted newborns may have behavioral effects,


motoric delays, language delays

Marijuana


• Contributes to slower fetal growth, low birth weight


• Babies of women who regularly used marijuana show


increased tremors and startling, suggesting immature


development of the nervous system.

Study by Goldschmidt et al. (2000) indicates prenatal exposure


to marijuana can result in


-increased hyperactivity


-impulsivity


-problems paying attention


-increased delinquency and aggressive behavior

Cocaine


• Cocaine use during pregnancy increases risk of stillbirth, low


birth weight, and birth defects.


• Infants are excitable, irritable, or lethargic; sleep is disturbed


• Suggestions of delays in cognitive development even at 12


months of age


• Prenatal exposure linked to lower receptive and expressive


language abilities at older ages

Alcohol


• Heavy alcohol consumption during pregnancy can result in fetal


alcohol syndrome (FAS).

FAS babies


-often smaller, with smaller brains


-facial features include widely spaced eyes, underdeveloped upper jaw,


flattened nose


• Psychological characteristics appear to reflect dysfunction of the


brain.


• Maladaptive behaviors such as poor judgment, distractibility, and


difficulty perceiving social cues are common.

Caffeine


• Research regarding caffeine consumption is


inconsistent


-Several studies have found that pregnant women who take in


a good deal of caffeine are more likely than nonusers to have


a miscarriage or a low-birth-weight baby.

Cigarettes


– Consist of nicotine, carbon monoxide, and hydrocarbons (tars)


-Nicotine and carbon monoxide pass through placenta and reach the fetus


-Nicotine stimulates the fetus; long-term effects unknown


-Carbon monoxide decreases amount of oxygen available to the fetus


-Connected with impaired motor development academic delays, learning


disabilities, mental retardation, and hyperactivity


• Smokersbabies likely to be smaller than those of nonsmokers


-Babies of smokers more likely to be stillborn or to


die soon after birth


• Men who smoke are more likely to produce abnormal sperm.


-Babies of fathers who smoke have higher rates of birth


defects, infant mortality, lower birth weights, and


cardiovascular problems.

ParentsAge

Older fathers more likely to produce abnormal sperm


• 20s ideal age for women to bear children


• Teenage pregnancy can result in higher incidence of


infant mortality and low birth weight.


• Stillborn or preterm babies increase as age of mother


increases; adequate prenatal care decreases this


likelihood even for first-time older mothers.