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55 Cards in this Set

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Neutrophil locomotion process is stimulated by:

Chemotactic factors

The marginating oool of neutrophils is located:

On the walls of blood vessels

The cellular structure that differentiates the promyelocyte from the myeloblast are the:

Primary granules

Tissue basophils are known as_______ cells?

Mast

What is the name of the circulating form of macrophages?

Monocytes

The function of the T lymphocyte is to:

Participate in cellular immunity

T lymohocytes are cells that differentiate in the:

Thymus

B lymohocytes are cells that differentiate in the:

Bone marrow

Plasma cells originate from:

B lymohocytes

The cells that produce immunoglobulins are:

B lymohocytes

What are the major leukocytes found in the peripheral blood

Lymphocyte


Monocyte


Granulocytes



NOT HISTIOCYTES

Leukocytes can be devided based on their:

Function

List the types of granulocyte

Monocyte


Eosinophils


Neutrophils


Basophils



NOT LYMPHOCYTES

Which granulocyte lasts the longest in the perioheral blood?

Neutrophils

The easiest way to differentiate granulocytes from one another is to compare:

Color

The area of the hematopoetic process is where the granulocytic cells proliferate and mature

Bone marrow

List the order of maturation for granulocytic cells

Myeloblast


Promyelocyte


Myelocyte


Metamyelocyte


Band neutrophil


Segmented neutrophil

A diagnostic characteristic of a myeloblast is:

Auer rods

An easy way to help in the differentiation of the granulocytes in the bone marrow would be to:

Look at the color of the cytoplasm


Compare the nucleus to the cytoplasm size


Look for the color of the granules present

Are fused lysomes, needle like inclusions, normal or pathologic?

Pathologic

The best way to recognize a segmented neutrophil from other is the presence of:

Filamentous lobes

The granulocyte type has large orange granules

Eosinophil

This neutrophil has large dark purple granules

Basophils

This type of granulocyte has very fine granulation which stains pinkish with wrights stain

Neutrophil

This type of granulocyte has an indented nucleus with a loght blue, lacy looking cytoplasm:

Monocyte

This type of granulocyte has a round to oval shaped nucleus with light blue cytoplasm:

Lymphocyte

The normal referance range for segmented neutrophils is:

40 to 74%

Normal referance range for monocytes in the blood is

2 to 6%

When a lymphocyte is seen in the peripheral blood smear, it distinguished based on

Nothing, you can't tell them apart

This type of leukocyte typically circulates between the lymphatic system and the circulatory system

Lymphocyte

The term "left shift" refers to:

Immature granulocytes



And is most likely do to

Bacterial infection

The neutroohil locomotion process is stimulated by

Chemotactic factors

Hyposegmentatiin is characteristic of the _____animaly

Pelger-Heut

Hypersegmentation of neutrophils is defined as more that ____ segments

5

Signs associated eith Gaucher's disease

Hepatoslenomegaly, gaucher cells in BM , elevated serum acid phosphatase

Classical description of MONO

Soar throat, fever, swollrn cervical lymph nodes


Absolute lymphocytosis


> 10% variant lymphocytes



Not left shift

Criteria for diagnosis of MONO

Positive heterophil antibody test


Or EBV antibody titer


Russle bodies are found in mott cells and consist of

Aggregates of gamma globulins

T/F all types of leukocyte s can exist in either a leukoenic or leukocytic state

FALSE

Cause of Eosinophils

Hay fever


Parasites


Asthma


Allergic reaction

Hereditary disorder with impaired chemotaxis and delayed bacterial killing? Neutrophils have gigantic granules.

Chediak-higashi

Purple-red inclusions made of RNA are found in this disease

May - Hegglin

What disease is related to a microbicidal activity defect. Can ingest but cant kill the organism

Chronic Granulomatous Disease

Foam cells are associated with which disorder of lipid metabolism

Neimann-Pick

What cell is most affected with AIDS

Lymphocyte

In AIDs the number of circulating CD4 + T cells are

Decreased

The most frequent cause of a nonmalignant increase in total leukocyte count is

An increase in neutrophils

A disorder associated eith basophilia is

Polycythemia Vera

What disorder is suspected if monocytosis is seen on a peripheral smear

TB

Leukocytopenia is generally associated with whick leukocyte

Segmented neutrophil

What morphological abnormality is associated with sever burns, infectious states, malignancies or drug therapy

Toxic granulation

What morphological abnormality is associated with viral infections, burns, drugs and May-hegglin

Dohle bodies

What morphological abnormality is associated with dumbell or eye glass shsped nucleus

Pelger-Heut

This genetic disorder has Dohle-like bodies in neutrophils, abnormally large and poorly granulated platelets and thrombocytopenia

May-hegglin

Common finding on blood smear in Chediak-higashi

Very large granules due to abnormal lysosomal development