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83 Cards in this Set

  • Front
  • Back

How many bones does the viscerocranium have?

14 facial bones! (plus frontal bone)nasal - 2lacrimal - 2 Palatine - 2Zygomatic - 2Vomer - 1 Mandible - 1Maxilla - 2 Inferior Nasal Conchae - 2

How long does face development take?

Between 4-8 weeks of gestation. The mandible is first to develop at 4th week

What are the 2 main features of skull?

1. Protect brain


2. Protect facial structures

How can you divide the neurocranium?

1. Calvarium (roof) consists of frontal, parietal, occipital


2. Cranial Base (floor) has some of the calvarial bones: frontal, ethmoid, cribiform plate (transmit the olfactory nerves), sphenoid, temporal and parietal, occipital


6 bones totally

What is the face derived from?

Derived from 5 parts of tissue: facial primordia Begins at week 4 in the uterus. Finished by week 8

How many buds of tissue does the embryo have?

5 buds of tissue all from mesenchyme (from neural crest)


1. Frontonasal prominence -frontal bone


2. Maxillary prominence (x2) -2 maxilla


3. Mandibular prominece (x2) -x2 mandible


Also have stomodeum in the middle - goes on to form the opening of the oral cavity

What happens in the beginning of 4th week?

the 5 buds


1st pharyngeal arch: maxilla + mandible prominences

What happens in the end of 4th week?

Have 2 nasal placodes 
At the front of frontonasal prominences. They are bits of mesenchyme which will go on to form nasal tissue. 

Have 2 nasal placodes


At the front of frontonasal prominences. They are bits of mesenchyme which will go on to form nasal tissue.

Week 5

You have mesenchymal cells proliferating at the border of the placodes. These are known as medial nasal prominence - becomes nasal septum and fultrum of upper lip.
You also have the lateral nasal prominence - goes to become the nasal ala (side of...

You have mesenchymal cells proliferating at the border of the placodes. These are known as medial nasal prominence - becomes nasal septum and fultrum of upper lip.


You also have the lateral nasal prominence - goes to become the nasal ala (side of the nose)



Week 6

Looks more like human.
The 2 maxillary prominences are getting bigger and they are squashing the two medial nasal prominences to form the nose and upper lip.  

Looks more like human.


The 2 maxillary prominences are getting bigger and they are squashing the two medial nasal prominences to form the nose and upper lip.

week 7

Cleft Lip - What is it?

Definition: a common pathology of max-fax, esp paediatrics.


It is a failure of the 2 medial nasal prominences to FUSE TOGETHER (between week 4-6)




prevalence: 1 in 700 live births



What are the categories of cleft lip?



1. unilateral or bilateral


2. complete or incomplete




-left is more common than the right.


-incomplete means it doesnt affect the nasal septum, only affects the upper lip.


-complete = affects the upper lip, fultrum and nasal septum



What is the main issue with cleft lip?

feeding and articulations

when do cleft lip surgery takes place?

Usually repair within 10 weeks of birth.


RULE of 10s: operate within 10 weeks, when baby weighs 10 Lb and has 10g of Haemoglobin.




-if cleft is extensive, may take more than one surgery

What is cleft palate?

Related but NOT the same.


Failure of fusion of the medial nasal prominences.


Cleft palate occurs between 6-8 weeks of development.


Cleft palate can also occur with cleft lip.

What is the classification system of cleft palate?

Same as cleft lip.


1. Unilateral incomplete - just hard and soft palate, not the lip


2. Unilateral complete - all of palates and lip and going up


3. bilateral complete - most severe.




Needs to be repaired because of feeding and articulations issues

When is cleft palate repaired?

-a little later than cleft lip


-between 6 to 12 months. In the mean time to fill the deficit in the palate, they put a little plastic plate (known as the palatal obturator) that will help the baby feed until surgery

What are sutures?

-development of the neurocranium 

-metopic suture runs from frontal fontanelle to bridge of the nose 

-development of the neurocranium




-metopic suture runs from frontal fontanelle to bridge of the nose

what joints are sutures?

-fibrous joints, unique to the skull


-give them a lot of stability


-fuse completely at age 25-30


EXCEPTION: metopic suture (cant see normally) runs across the frontal bone, fuses in childhood (age 12)

Difference between children and adult sutures?

-fontanelles: soft depressions


1. Frontal in front


2. Occipital in the back




-usually fuse by 1-2 years


-allow for skull expansion as the brain grows


-also useful in radiology for cranial USS probing in the fontanelles to scan brain of infant

how does the skull look like in a baby?

What happens when the sutures fuse prematurely?

CRANIOSYNOSTOSIS




-1 in 2000 to 1 in 5000 development (RARE than cleft series)


-definition: premature fusion of 1 or more cranial sutures




-restricts skull growth in one direction


-you get compensatory growth in the direction that is perpendicular to the fused suture


-result: a very bizarre looking skull




-may need surgery to ensure that the brain development is not restricted




-simple: affects 1 suture


-complex: affects >1 sutures



What is trigonocephaly?

-5% of total deformity 
-premature fusion of the metopic suture 
-skull expands parallel to the direction of the suture 
-strange triangular appearance 
-can draw the eyes close together 

-5% of total deformity


-premature fusion of the metopic suture


-skull expands parallel to the direction of the suture


-strange triangular appearance


-can draw the eyes close together



What is scaphocephaly?

-fusion of sagittal suture 
-most common type of craniosynostosis 
-restricts lateral growth of skull, so increased AP growth 
-result: narrow elongated skull (boat-shaped) 

-fusion of sagittal suture


-most common type of craniosynostosis


-restricts lateral growth of skull, so increased AP growth


-result: narrow elongated skull (boat-shaped)

What is plagiocephaly?

-when you have early fusion of one of the coronal sutures
-you have an assymmetrical growth 
-causes restriction on fused side 
-compensation: growth more on the opposite side 

-can also happen in the back (lamboid suture) 

-when you have early fusion of one of the coronal sutures


-you have an assymmetrical growth


-causes restriction on fused side


-compensation: growth more on the opposite side




-can also happen in the back (lamboid suture)

What is brachycephaly?

Opposite of scaphycephaly.


You have fused coronal sutures on both sides. AP growth restriction, so increase in lateral growth - round skull is the end result. You also get retrusion of the forehead




Can be Associated with:


-cruzon syndrome


-alpert syndrome


-carpenter syndrome




(rare genetic syndromes)

What is the management of brachycephaly?

-complex


-if not bad, can be left (only small aesthestic issue)


-if it is raising the ICP, then max-fax operate


-if growth restriction affects forehead: FRONTO-ORBITAL advancement, where they cut through the skull at the level of suture and orbit, take block out and move it forward, so skull can continue to grow





Management of scaphocephaly?

Reopen the suture so that they can continue to grow normally

How do the muscles of facial expression develop?

-all the facial muscles originate from the SECOND PHARYNGEAL arch


-all are innervated by CN VII (facial nerve) so unilateral facial nerve palsy affects all the muscles





How do you classify the muscles of facial expression?

-can classify them into 3 groups.


1. Superiorly - ORBITAL GROUP


2. Nose - NASAL


3. Mouth - ORAL




42 muscles in total

What is the orbital group made up of?

1. orbicularis oculi: has 2 parts


-inner palpebral part


-outer orbital part


-both work together to work the eyelids




2. Corrugator Supercilii


-above and behind OO


-contract to draw the eyebrows together



What is the nasal group made up of?

1. Nasalis


-has 2 parts: transverse and alar


-transverse part compresses nostrils


-alar part opens nostrils




2. Procerus


-above nasalis


-pulls eyebrows downwards


-works together with CS




3. Depressor septi nasi


-pulls nose inferiorly which can open the nostrils

What is the oral group made up of?

1. Orbicularis Oris


-surrounds the mouth


-purses the lip when contracts




2. buccinator


-deep to the other facial muscles


-pulls cheek inwards, which prevents buildup of food in the mouth



What are the symptoms of facial nerve paralysis?

-important signs: lose forehead wrinkles, lower lid (ectropion)


-cant smile normally



Whats the most common cause of CN VII palsy?

-Bell's palsy


-Lower motor neuron lesion


-unknown cause, can be viral origin




-given steroids, dont know how it works


-usually resolves without meds in 3-6 months




DDx: Stroke - upper motor neuron lesion. Always look at the forehead - if they have stroke, forehead is SPARED

How do you classify head and neck cancers?

-complex cancers because of difficult anatomy


-can break down cancer based on region




1. oral cancer


2. pharyngeal: naso- and oro-


3. Laryngeal

How do you manage Head and neck cancers ?



chemotherapy


Radiotherapy


Surgery




Usually diagnosis is late, so palliative care is often the solution

What is oral cancer made up of?

90% squamous cell carcinoma



Which organ is most involved in oral cancer?

50% is tongue (lateral surface)


-usually painless




-late stage - invades the lingual nerve, so can cause pain

What are the risk factors and prevalence of oral cancer?

-it is associated with smoking, alcohol and HPV virus




-high prevalence in the Indian subcontinent - because of chewing betel nut and tobacco



What is the usual treatment for Oral cancer?

Usually treated with a combination of surgery +/- radiotherapy +/- chemotherapy




(glossectemy = removal of tongue)




-lymph node dissection also key

What is the anatomy of the oral cavity?

-tongue 
-soft palate 
-tonsils 
-2 fauces on either side (like pillars) 

-tongue


-soft palate


-tonsils


-2 fauces on either side (like pillars)

What is a free fibula flap?

-used in advanced head and neck cancers


-used to reconstruct the mandible, a flap of tissue is taken from the fibula




-fibula + skin island + cuff of muscle + peroneal artery and vein





what is pharyngeal cancer?

-can be divided into naso-, oro-





what is the histology of Oropharynx cancer?

-75% squamous cell, rest are lymphoma



Where is the common site for oro-pharynx cancer?

-Tonsils and the Faucial pillars

What is oropharynx cancer usually associated with ?

Smoking/HPV



What are symptoms of Oropharynx cancer?

-throat pain


-globus sensation (sensation of something in the throat)



What is the treatment for oropharynx cancer?

Radiotherapy +/- chemotherapy




If there are neck node metastases, then only is surgery done

What is the histology of nasopharynx cancer?

Mostly squamous cell carcinoma



What are risk factors of nasopharynx cancer?

-chinese descent


-EBV

Where is the highest incidence of nasopharynx cancer?

SOUTHEAST asia (china, Hong kong, taiwan, malaysia)



What are symptoms of nasopharynx cancer?

-can cause facial pain (CN V) because it can invade through the foramen ovale

What is treatment of nasopharynx cancer?

-Radiotherapy mainly




-survival rate (if the cancer has a protracted course) is 60-80% in 5 years (decent cancer)

What is FNE?

Fine nasal endoscopy

What is the histology of laryngeal cancer?

Mostly squamous cell



Which organs are affected in laryngeal cancer?

-supraglottis


-glottis


-subglottis



What is the most common symptom of laryngeal cancer?

-glottic cancer - early presentation because of dysphonia (Hoarse voice) so early Dx and better outcomes




-supraglottic cancer - tends not to affect voice and can grow to large size before causing DYSPHAGIA (bad outcomes)




-subglottic cancer - RARE but similar presentation to supraglottic cancer

What is the anatomy of the larynx?

Divide into 3 parts: 
-supraglottis is above the level of true vocal cord
-glottis is on the level of the true vocal cord
-subglottis is on the level before the true vocal cord 

Divide into 3 parts:


-supraglottis is above the level of true vocal cord


-glottis is on the level of the true vocal cord


-subglottis is on the level before the true vocal cord

Why has the incidence of laryngeal cancer fallen since the 1990s?

because less men have smoked since 1990




-LARYNGEAL CANCERS HEAVILY LINKED TO SMOKING

What is the incidence of supraglottic cancer?

40%



What is the presentation of supraglottic cancer?



-dysphagia


-metastatic neck node


-late presentation is common

How do you manage supraglottic cancer?

-Supraglottic laryngectomy + radiotherapy


-do only a total laryngectomy if there is residual/recurrent disease (or metastatic neck nodes)

How common is glottic cancer?

60%

What is the symptom of glottic cancer?

Dysphonia - usually an early presentation

What is the management of glottic cancer?

-Radiotherapy for early tumours (there is a 95% cure rate for T1 lesions)




-total laryngectomy and neck dissection for tumours which are residual or recurrent

What is the most important thing to remember in facial traumas?

-AIRWAY management




-if they have facial trauma, then they probably have fractures/injuries elsewhere

How are facial traumas divided?

-upper 1/3: frontal


-middle 1/3: small facial bones


-lower 1/3: mandible

What are orbital rim fractures?

-normally occur at suture lines (weakest point)


-superior orbital rim is the STRONGEST

What are the bones forming the orbital rim?

frontal - upper eyebrow 
zygomatic - side 
maxilla - underneath + floor 
side - lacrimal/ethmoid/palatine 

Sphenoid - back 

frontal - upper eyebrow


zygomatic - side


maxilla - underneath + floor


side - lacrimal/ethmoid/palatine




Sphenoid - back

How can you test for the fracture of the zygomatic arch?

-trace down elephant's line on the side of an XRAY 

-trace down elephant's line on the side of an XRAY

What is an orbital blowout fracture?

-when there is raised pressure intraorbital


-usually from something flying at the eye


-partial HERNIATION of the orbital contents through the weakest part of the cavity


(usually FLOOR)




-fat and blood usually spill out into the maxillary sinus




-also entrapment of the inferior rectus muscle (enables eye to look downwards) so paralysis of upward gaze, so inferior rectus is permanent contraction

How are maxillary fractures classified ?

-Le Fort classification 

-all need surgical management 

-Le Fort classification




-all need surgical management

What is Le Fort type 1?

horizontal fracture that separates teeth from upper face (fracture passes from the inferior alveolar ridge to below the maxillary sinus)




(floating palate) - so teeth moves separate to the nose

What is Le Fort type 2?

base of pyramid - alveolar ridge


apex - nasofrontal suture




-floating nose and palate

Le fort 3?

Most severe type of fracture




-fracture line all the way across separating the viscerocranium from neurocranium





What are the major incidences of mandibular fractures?

-Most common place is usually the left side of the mandible (left body) 

WHY? most people are right-handed so puncture left side of mandible 

-condyles, body and angle are most common

-ramus and coronoid process are rare 

-Most common place is usually the left side of the mandible (left body)




WHY? most people are right-handed so puncture left side of mandible




-condyles, body and angle are most common




-ramus and coronoid process are rare

What percentage are bifocal in mandibular fractures?

60%




Why? because the mandible is a BONY ring

What are the symptoms of mandibular fractures?

-Trismus (because of spasm of temporalis)




-malocclusion (cant bite cos of malalignment of maxilla and mandible)




-paresthesia to the chin (disruption to the inferior alveolar nerve)

Anatomy of the maxilla and mandible (sagittal view)

inferior alveolar nerve (V3 branch) enters the mandible, travels through the bone and emerges through the mental foramen to become the mental nerve (which supplies the lower lip) 

inferior alveolar nerve (V3 branch) enters the mandible, travels through the bone and emerges through the mental foramen to become the mental nerve (which supplies the lower lip)

How easy is it to get a frontal bone fracture?

NOT EASY


need 100-200x force of gravity

What are the symptoms of frontal bone fractures?

-forehead paresthesia (because of disruption of supraorbital nerve)




-Rhinorrhea ( runny nose, but actually it is CSF leak)