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16 Cards in this Set
- Front
- Back
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types of post synaptic cells
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neuron
glandular tissue muscle cell |
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types of neuron-neuron synapses
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axosomatic
axodendritic axoaxonic |
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NT binding to postsyanptic receptor causes...
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...open specific ion channels
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NT bindindg to presynaptic receptor causes...
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...modulation of NT synthesis or release; feedback
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two main mech for terminating synaptic signal
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enzyme degredation
uptake |
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agnoist
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mimics effect of NT of interst at synapse
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endogenouse
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naturally occuring w/in tissue
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exogenous
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artificially put into tissue
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NT
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endogenous agonist at own receptors
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direct agonist
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bind to NT receptor protein
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indirect agonist
e.g. |
dont bind to receptor but affect action of NT indirectly
e.g. drugs that facilitate synthesis or release of transmitter or prevent enzymatic degredation |
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antagonist
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reduce/blocks action of another agonist
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direct antagonist
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bind to receptor to prevent agonist from binding
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indirect antagonist
e.g. |
dont bind to receptor protein but interfere indirectly
e.g. drugs that decrease NT sytnehsis or release, enhance enzymatic degradation of NT in synaptic cleft |
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selective
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act on one receptor subtype but not another
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nonselective
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act on all receptor subtype of given NT
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