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16 Cards in this Set

  • Front
  • Back
types of post synaptic cells
neuron
glandular tissue
muscle cell
types of neuron-neuron synapses
axosomatic
axodendritic
axoaxonic
NT binding to postsyanptic receptor causes...
...open specific ion channels
NT bindindg to presynaptic receptor causes...
...modulation of NT synthesis or release; feedback
two main mech for terminating synaptic signal
enzyme degredation
uptake
agnoist
mimics effect of NT of interst at synapse
endogenouse
naturally occuring w/in tissue
exogenous
artificially put into tissue
NT
endogenous agonist at own receptors
direct agonist
bind to NT receptor protein
indirect agonist

e.g.
dont bind to receptor but affect action of NT indirectly

e.g. drugs that facilitate synthesis or release of transmitter or prevent enzymatic degredation
antagonist
reduce/blocks action of another agonist
direct antagonist
bind to receptor to prevent agonist from binding
indirect antagonist

e.g.
dont bind to receptor protein but interfere indirectly

e.g. drugs that decrease NT sytnehsis or release, enhance enzymatic degradation of NT in synaptic cleft
selective
act on one receptor subtype but not another
nonselective
act on all receptor subtype of given NT