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19 Cards in this Set

  • Front
  • Back

The drug experience is a product of more factors than just the drugs pharmacological action.




What are those factors?

Characteristics of the drug user


The genetic makeup, gender, age, drug tolerance, personality, psychological set about the drug (knowledge, attitudes, expectations, thoughts)




Setting in which the drug is used


Laws pertaining to drug use in the community, immediate physical environment, whether other people are present at the time.



National survey results show that in the U.S. we use a variety of drugs. Which 3 are the most commonly used?

Alcohol, cigarettes, marijuana

The heaviest and the most frequent illicit use is amongst with age group?

18-25

What manual is used for a formal definition of substance use disorders?

DSM-5

There are 6 major ways to classify a drug. What are they?

Origin


Therapeutic use (how a drug is used to treat or modify something in the body)


Site of drug action (where in the body the drug is causing physical changes)


Chemical structure


Mechanism of action (how a drug produces its drug effects)


Street name

Benefits and downsides to the Prohibition Era of the 1920's

Downsides


Much wider use of liquid marijuana for nonmedical purposes




Drinking habits shifted to distilled spirits instead of beer.




Advent of speakeasy (saloon operating w/out a license.




Criminal groups distributing alcohol




Benefits


Rate of drinking, # of deaths from liver cirrhosis, admission rates to hospitals for treatment, arrest rates for alcohol-related offenses all decreased.

Club drugs

MDMA (ecstasy)-stimulant and psychedelic effect


GHB-intoxicating, sedative, euphoriant & growth hormone


Ketamine (special k)-anesthetic


Rohypnol (roofies)-anterograde amnesia


Methamphetamine-stimulant affecting CNS

Main mechanisms through which society establishes formal guidelines for regulating drugs and drug use

Legislation


Beliefs about drugs

"War on Drugs" implemented and its original focus

1980's


To catch drug smugglers ad sellers and implementation of a "zero-tolerance" approach to drug users, including casual users of drugs.

The 2 drugs that are associated with death in the US, but were overlooked during the "War on Drugs".

Tobacco & Alcohol

Problematic issues with drug testing

Possible infringement on constitutional rights of privacy




Relationship between a positive test result and actual job performance




Accuracy of the drug tests

Brain cells

Neurons

How do neurons transmit info?

Information is gathered by the dendrites and travels along the axon as an electrical signal (action potential) then is held by the axon terminals and the chemicals (neurotransmitters) stored in the terminal button are released into the synapse and trigger activity into the adjacent neuron. The neurotransmitters occupy a receptor and binds.

Lock-key mechanism

Receptors are the locks and must be opened before the neuron fires into the synapse. The receptors are unlocked when the neurotransmitter chemicals are released into the terminal buttons. The neurotransmitters are the keys, they must fit the receptor to trigger an event (neural firing)

Description of a drug that alters neural transmission by occupying a receptor site and blocking transmission.

Antagonist

Two main sections of CNS

Brain and Spinal Cord

4 common brain imaging tools

Electroencephalography (EEG)-measuring brain's electrical activity through the scalp


Computerized axial tomography (CAT)-passing x-rays through the head in a circular pattern to get a 3-dimensional image of the brain


Positron-emission tomography (PET)-injecting weak radioisotopes into the brain and various regions can be assessed


Magnetic resonance imaging (MRI)-a strong magnetic field is passed through a person's head. Localized and detailed brain image

Naturally occurring morphine

Endorphins

SSRI

Selective serotonin reuptake inhibitor




Prozac is a popular brand name




Treats the symptoms of depression more effectively than tricyclics and are associated with fewer side effects for many users.