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6 Cards in this Set
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what can happen to kids who ingest vagisil or other topical anesthetics such as hurricane spray
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Methemoglobinemia (they will turn blue)
give them methyline blue |
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Toxic dose of acetaminophen?
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150 mg/kg
Phase 1 0-24 hours after ingestion Patients may be asymptomatic or report anorexia, nausea or vomiting, and malaise Physical examination may reveal pallor, diaphoresis, malaise, and fatigue Phase 2 18-72 h after ingestion Patients generally develop right upper quadrant abdominal pain, anorexia, nausea, and vomiting Right upper quadrant tenderness may be present Tachycardia and hypotension indicate ongoing volume losses Some patients may report decreased urinary output (oliguria) Phase 3 72-96 h after ingestion Patients may have continued nausea and vomiting, abdominal pain, and a tender hepatic edge Hepatic necrosis and dysfunction are associated with jaundice, coagulopathy, hypoglycemia, and hepatic encephalopathy Acute renal failure develops in some critically ill patients Death from multiorgan failure may occur Phase 4 4 d to 3 wk after ingestion Patients who survive critical illness in phase 3 have complete resolution of symptoms and complete resolution of organ fa |
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Toxic metabolite of acetaminophen? tx?
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N -acetyl-p-benzoquinone imine (NAPQI)
use N-acetylcystine (NAC) as tx, restores glutathione for reducing the toxic metabolite |
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Max daily dose of acetaminophen?
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4 g
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dose of NAC for tylenol OD
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150
remember 150 mg/kg is the lethal dose so these go together |
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Why can you not give phenytoin quickly?
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propylene glycol is in the mixture of phenytoin and can cause cardiovascular collapse
this is the reason for slow drip! |
