Unconsciousness And Excitatory Report

Serious adverse experiences are generally systemic in nature. The following types are those most commonly reported:
1- Central Nervous System
CNS manifestations are excitatory and/or depressant and may be characterized by circumoralparesthesia, lightheadedness, nervousness, apprehension, euphoria, confusion, dizziness, drowsiness, hyperacusis, tinnitus, blurred vision, vomiting, sensations of heat, cold or numbness, twitching, tremors, convulsions, unconsciousness, respiratory depression and arrest. The excitatory manifestations may be very brief or may not occur at all, in which case the first manifestation of toxicity may be drowsiness merging into unconsciousness and respiratory arrest (38) .