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12 Cards in this Set
- Front
- Back
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Define Transcription
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The process of mRNA from DNA, which ultimately is translated to make protein
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This transcription inhibitor is bactericidal for intra and extra cellular Mycobacterium
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Rifampin
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Rifampin is a drug affectin Prokaryotes.
T or F |
TRUE
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Rifampin is contraindicated in what patients?
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Those with hepatic disease
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Related antibiotics with similar MOA and SE's include: (2)
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rifapentine and rifabutin
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One of the DOC in the four-drug treatment for Mycobacterium avium complex (MAC)
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Rifabutin
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Toxin in many poison mushrooms
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Alpha-amanitin
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Causes inhibition of mRNA production in eukaryotes
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Alpha-amanitin
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Which 2 antibiotic cytotoxins are also transcription inhibitors?
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Actinomycin D and Doxorubicin
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CA of the breast and lung, as well as ALL and lymphoma are indications for the use of what transcription inhibitor?
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Actinomycin D
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Adverse effects shared by Actinomycin D and Doxorubicin?
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bone marrow suppression, alopecia, stomatitis, and overall immunosuppression
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What transcription inhibitor can caus red urine and dilated cardiomyopathy?
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DOXORUBICIN
(Doxo-RUBY-cin) Ruby for RED and red for HEART |
