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20 Cards in this Set

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Tyramine (MOA & PK)
MOA - Stimulates release of catecholamines
PK - Found in food, beer, beans cheese, meets, wine and yeast; inactivated by MAO
Tyramine (CU & T)
CU - N/A
T - Catecholamine excess especially when taken with MAO inhibitors
Ephedrine (MOA & PK)
MOA - Stimulates release of catecholamines and directly activates adrenoreceptors
PK - PO/IV; well absorbed and good CNS penetration; long duration of action
Ephedrine (CU & T)
CU - N/A
T - Anorexia, insomnia, hypertension, arrhythmias
Amphetamine (MOA & PK)
MOA - Stimulates release of catecholamines and blocks reuptake
PK - PO; well absorbed and good CNS penetration; long duration of action
Amphetamine (CU & T)
CU - Anorexiant, ADHD, narcolepsy
T - Restlessness, dizziness, tremor, hyperactive reflexes, anxiety, delirium, libido changes, paranoid hallucination, panic states, suicidal tendencies
Methamphetamine (MOA & PK)
MOA - Stimulates release of catecholamines and blocks reuptake
PK - PO; well absorbed and good CNS penetration; long duration of action
Methamphetamine (CU & T)
CU - Anorexiant, ADHD, narcolepsy
T - Restlessness, dizziness, tremor, hyperactive reflexes, anxiety, delirium, libido changes, paranoid hallucination, panic states, suicidal tendencies
Methylphenidate (MOA & PK)
MOA - Stimulates release of catecholamines and blocks reuptake
PK - PO; well absorbed and good CNS penetration; long duration of action
Methylphenidate (CU & T)
CU - Anorexiant, ADHD, narcolepsy
T - Restlessness, dizziness, tremor, hyperactive reflexes, anxiety, delirium, libido changes, paranoid hallucination, panic states, suicidal tendencies
Phenmetrazine (MOA & PK)
MOA - Stimulates release of catecholamines and blocks reuptake
PK - PO; well absorbed and good CNS penetration; long duration of action
Phenmetrazine (CU & T)
CU - Anorexiant, ADHD, narcolepsy
T - Restlessness, dizziness, tremor, hyperactive reflexes, anxiety, delirium, libido changes, paranoid hallucination, panic states, suicidal tendencies
Modafinil (MOA & PK)
MOA - Stimulates release of catecholamines and blocks reuptake
PK - PO; well absorbed and good CNS penetration; long duration of action
Modafinil (CU & T)
CU - Anorexiant, ADHD, narcolepsy
T - Restlessness, dizziness, tremor, hyperactive reflexes, anxiety, delirium, libido changes, paranoid hallucination, panic states, suicidal tendencies
Pemoline (MOA & PK)
MOA - Stimulates release of catecholamines and blocks reuptake
PK - PO; long duration of action
Pemoline (CU & T)
CU - Anorexiant, ADHD, narcolepsy
T - Restlessness, dizziness, tremor, hyperactive reflexes, anxiety, delirium, libido changes, paranoid hallucination, panic states, suicidal tendencies
Phenylpropanolamine (MOA & PK)
MOA - Weak sympathetic activity
PK - N/A
Phenylpropanolamine (CU & T)
CU - Weight reduction
T - N/A
Pseudoephedrine (MOA & PK)
MOA - Alters synaptic release of NE which in turn activates alpha receptors produces vasoconstriction
PK - PO; longer duration; not catechol (no COMT degradation); a1>a2>>>>>>B
Pseudoephedrine (CU & T)
CU - Nasal decongestant
T - Hypertension (systemic)