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12 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Acetylcholine (MOA & PK)
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MOA - Activates muscarinic and nicotinic cholinergic receptors
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PK - Rapidly metabolized by AChE (5-20 sec); poor oral absorption; quaternary amine; IV
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Acetylcholine (CU & T)
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CU - Glaucoma
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T - Autonomic excess
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Bethanechol (MOA & PK)
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MOA - Activates muscarinic receptors; increases parasympathetic activity
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PK - PO/SC; quaternary amine
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Bethanechol (CU & T)
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CU - GI disorders postoperative; neurogenic ileus; urinary retention; activates bowel and bladder smooth muscle
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T - Sweating, bradycardia, increased bowel activity, urination, blurred vision, miosis
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Pilocarpine (MOA & PK)
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MOA - Activates muscarinic receptors; increases parasympathetic activity
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PK - PO/topical ophthalmic; tertiary amine
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Pilocarpine (CU & T)
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CU - Glaucoma; Sjögren’s disease
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T - Sweating, bradycardia, increased bowel activity, urination, blurred vision, miosis
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Cevimeline (MOA & PK)
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MOA - Activates muscarinic receptors; increases parasympathetic activity
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PK - PO; tertiary amine
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Cevimeline (CU & T)
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CU - Dry mouth from Sjögren’s disease
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T - Sweating, bradycardia, increased bowel activity, urination, blurred vision, miosis
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Carbachol (MOA & PK)
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MOA - Activates muscarinic and nicotinic receptors; increases parasympathetic activity
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PK - Topical ophthalmic/intraocular; quartenary amine
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Carbachol (CU & T)
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CU - Glaucoma
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T - Sweating, bradycardia, increased bowel activity, urination, blurred vision, miosis
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Varenicline (MOA & PK)
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MOA - Partial agonist to CNS a4, B2 type nicotinic receptor
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PK - PO; tertiary amine
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Varenicline (CU & T)
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CU - Smoking cessation
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T - Nausea, headache, sleep disturbances, neuropsychiatric effects
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