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17 Cards in this Set
- Front
- Back
- 3rd side (hint)
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the physical barriers of the First line of defenses of innate immunity are?
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skin and mucos membranes:
Mucous membranes Mucus traps microbes and foreign substances Nose hairs trap and filter Cilia of upper respiratory tract propel trapped particles up and out |
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whate fluids of innate immunity defend against pathogens?
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Lacrimal apparatus of eye
Washing action of tears Lysozyme breaks down bacterial cell walls – also present in saliva, perspiration, nasal secretions, and tissue fluids Saliva washes mouth Urine cleanses urinary system Vaginal secretions, defecation and vomiting |
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whate chemicals of innate immunity defend against pathogens?
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Sebaceous (oil) glands secrete sebum – protective film, acid
Perspiration, gastric juice, vaginal secretions – all acidic |
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internal antimicrobial substances, phagocytes, natural killer cells, inflammation and fever are considered the body's?
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second line of deffense
(innate immunity) |
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what antimicrobial substance
Produced by lymphocytes, macrophages, and fibroblasts infected by viruses Prevents replication in neighboring uninfected cells? |
Interferons
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what antimicrobial substance
Proteins in blood plasma and plasma membranes “complement” or enhance certain immune reactions Causes cytolysis of microbes, promotes phagocytosis, contributes to inflammation? |
Complement
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what antimicrobial substance
Inhibit growth of bacteria by reducing available iron? |
Iron-binding proteins
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what antimicrobial substance are Short peptides that have a broad spectrum of antimicrobial activity
Can attract dendritic cells and mast cells that participate in immune responses |
Antimicrobial proteins (AMPs)
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the ______ molecule on a normal cell stops the nautral killer cell from destroying it?
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MHC I;
abnormal cells do not have this molecule so the NK cells kill it. it does this by secreting? |
perforin and granzymes
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the 2 major types of phagocytic cells are?
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macrophages and neutrophils
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the 1st cell to arrive to fight an infection begining phagocytosis is?
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neutrophil; the second are mononcytes the differentiate into?
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wondering macrophages
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what are the 5 steps of phagocytosis?
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chemotaxis
adherence ingestion digestion killing (Can Anyone Dance w/ Kings?) during phagocytosis |
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what is the stage of phagocytosis where chemicals from invading microbes attract phagocytes?
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chemotaxis
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what is the stage of phagocytosis where phagocytes attach to invaders?
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adherence
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what is the stage of phagocytosis where projections of the phagocytes called pseudopods ingest the invaders?
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ingestion
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what is the stage of phagocytosis where phagosomes and lysosomes form a large structure called a phagolysosome mixing chemicals?
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digestion
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what is the stage of phagocytosis where the chemicals provided by lysosomes, digestive enzymes, and oxidants kills the microbes?
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killing phase
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